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MSDS  : Resorcinol, 4-chloro-
CAS  : 95-88-5
SYNONYMS  : * 1,3-Benzenediol, 4-chloro- * 4-Chlororesorcin * p-Chlororesorcinol * 4-Chlororesorcinol * 6-Chlororesorcinol * C.I. 76510 * 2,4-Dihydroxychlorobenzene
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : VH0450000
CHEMICAL NAME : Resorcinol, 4-chloro-
CAS REGISTRY NUMBER : 95-88-5
BEILSTEIN REFERENCE NO. : 2042864
REFERENCE : 4-06-00-05684 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C6-H5-Cl-O2
MOLECULAR WEIGHT : 144.56
WISWESSER LINE NOTATION : QR CQ DG
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
Primary Irritant
SYNONYMS/TRADE NAMES :
* 1,3-Benzenediol, 4-chloro-
* 4-Chlororesorcin
* p-Chlororesorcinol
* 4-Chlororesorcinol
* 6-Chlororesorcinol
* C.I. 76510
* 2,4-Dihydroxychlorobenzene

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 5%
REACTION SEVERITY : Mild
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 46,185,1957

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 369 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Skin and Appendages - hair
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 15,607,1977

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 195 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - tremor
Behavioral - ataxia
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 46,185,1957

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 2 gm/kg
SEX/DURATION : female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 2(4),325,1983

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7016
No. of Facilities: 2984 (estimated)
No. of Industries: 3
No. of Occupations: 3
No. of Employees: 26087 (estimated)
No. of Female Employees: 19986 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Negative: N crassa-aneuploidy

EPA GENETOX PROGRAM 1988, Inconclusive: Mammalian micronucleus

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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