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MSDS  : 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol, (1-alpha,3-beta,5Z,7E,24R)-
CAS  : 56142-94-0
SYNONYMS  : * (24R)-24-Hydroxycalcitriol * (1-alpha,3-beta,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25 -tetrol * Ro 21-7729 * 1-alpha,24(R),25-Trihydroxyvitamin D3
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : VS2878300
CHEMICAL NAME : 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol,
(1-alpha,3-beta,5Z,7E,24R)-
CAS REGISTRY NUMBER : 56142-94-0
LAST UPDATED : 199806
DATA ITEMS CITED : 1
MOLECULAR FORMULA : C27-H44-O4
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* (24R)-24-Hydroxycalcitriol
* (1-alpha,3-beta,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25
-tetrol
* Ro 21-7729
* 1-alpha,24(R),25-Trihydroxyvitamin D3

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 812 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Lungs, Thorax, or Respiration - respiratory stimulation
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu
Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
Volume(issue)/page/year: 17,4615,1989

*** END OF RECORD ***
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NAMECAS
4,21-Secoajmalan-17-ol, 4-(2-(diethylamino)ethyl)-,(17R)- 58893-13-3
4,21-Secoajmalan-17-ol, 4-(2-(diethylamino)ethyl)-,(17R,20-alpha)- 58918-26-6
4,21-Secoajmalan-17-ol, 4-(2-piperidinoethyl)-,(17R)- 58893-14-4
4,21-Secoajmalan-17-ol, 4-(2-piperidinoethyl)-,(17R,20-alpha)- 58918-27-7
4,5-Secoandrost-5-en-3-one, 17-beta-hydroxy- 58918-27-7
7,13-alpha-Secoberbin-13-alpha-one,9,10-(2-bromomethylenedioxy)-7-methyl-2,3-(methylenedioxy)- 80416-87-1
7,13a-Secoberbin-13a-one,7-methyl-2,3:9,10-bis(methylenedioxy)- 130-86-9
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9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol,24-cyclopropyl-, (1-alpha,3-beta,5Z,7E,22E,24S)- 112965-21-6
9,10-Secocholesta-5,7,10(19)-triene-1,3-diol,(1-alpha,3-beta,5E,7E)- 65445-14-9
9,10-Secocholesta-5,7,10(19)-triene-1,3-diol,(1-alpha,3-beta,5Z,7E)- 41294-56-8
9,10-Secocholesta-5,7,10(19)-triene-3,24-diol,(3-beta,5Z,7E)- 58239-34-2
9,10-Secocholesta-5,7,10(19)-triene-1,3,23,25-tetrol,26,26,26,27,27,27-hexafluoro-,(1-alpha,3-beta,5Z,7E,23S)- 114489-80-4
9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol,(1-alpha,3-beta,5Z,7E,24R)- 56142-94-0
9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol,(1-alpha,3-beta,5Z,7E,24R)- 57333-96-7
9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,26,26,26,27,27,27-hexafluoro-,(1-alpha,3-beta,5Z,7E)- 83805-11-2
9,10-Secocholesta-5,7,10(19)-triene-3,24,25-triol,(3-beta,5Z,7E)- 40013-87-4
9,10-Secocholesta-5,7,10(19)-triene-3,24,25-triol,(3-beta,5Z,7E,24R)- 55721-11-4
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Sabia parviflora Wall.ex Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family SabiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990 55721-11-4
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol 67-97-0
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16,17-Seco-13-alpha-estra-1,3,5,7,9-pentaen-17-oicacid, 3-methoxy-, (+-)- 15372-34-6
16,17-Secoestra-1,3,5(10),6,8-pentaen-17-oic acid,3-methoxy- 15372-34-6
16,17-Secoestra-1,3,5(10)-trien-17-oic acid,3-hydroxy- 482-49-5
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4,8-Secosenecionan-8,11,16-trione,15,20-dihydro-12-(acetyloxy)-15,20-epoxy-4-methyl-,(12-beta,15-beta,20S) 90364-92-4
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16,19-Secostrychnidine-10,16-dione,21,22-dihydro-19-methyl- 36297-66-2
16,19-Secostrychnidine-10,16-dione,14-hydroxy-19-methyl- 22029-96-5
Saccharum officinarum Linn., leaf extractSUBSTANCE DEFINITION :Plant belonging to the family PoaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984 22029-96-5
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17,18-Secoyohimban-16-carboxylic acid,18,19-didehydro-17-hydroxy-, methyl ester, sulfate 66634-25-1
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