*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WB2930000
CHEMICAL NAME : Sodium hexavanadate
CAS REGISTRY NUMBER : 12436-28-1
LAST UPDATED : 199701
DATA ITEMS CITED : 23
MOLECULAR FORMULA : O15-V6.4Na
MOLECULAR WEIGHT : 637.60
WISWESSER LINE NOTATION : NA4 VA6-O17
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 140 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJSNAO American Journal of Syphilis and Neurology. (St. Louis, MO) V.1-19,
1917-35. For publisher information, see AJSGA3. Volume(issue)/page/year:
1,347,1917
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 350 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJSNAO American Journal of Syphilis and Neurology. (St. Louis, MO) V.1-19,
1917-35. For publisher information, see AJSGA3. Volume(issue)/page/year:
1,347,1917
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 105 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJSNAO American Journal of Syphilis and Neurology. (St. Louis, MO) V.1-19,
1917-35. For publisher information, see AJSGA3. Volume(issue)/page/year:
1,347,1917
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 140 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJSNAO American Journal of Syphilis and Neurology. (St. Louis, MO) V.1-19,
1917-35. For publisher information, see AJSGA3. Volume(issue)/page/year:
1,347,1917
*** REVIEWS ***
TOXICOLOGY REVIEW
85DHAX "Medical and Biologic Effects of Environmental Pollutants Series,"
Washington, DC, National Academy of Sciences, 1972-77
Volume(issue)/page/year: V,46,1974
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 0.05 mg(V2O5)/m3 JAN 1993
OEL-BELGIUM:TWA 0.05 mg(V2O5)/m3 JAN 1993
OEL-DENMARK:TWA 0.03 mg(V2O5)/m3 JAN 1993
OEL-FINLAND:TWA 0.5 mg(V2O5)/m3 JAN 1993
OEL-FRANCE:TWA 0.05 mg(V2O5)/m3 JAN 1993
OEL-GERMANY:TWA 0.05 mg(V2O5)/m3 JAN 1993
OEL-HUNGARY:TWA 0.05 mg(V2O5)/m3;STEL 0.1 mg(V205)/m3 JAN 1993
OEL-JAPAN:TWA 0.5 mg(V2O5)/m3 JAN 1993
OEL-THE NETHERLANDS:TWA 0.5 mg(V2O5)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.25 mg(V205)/m3 JAN 1993
OEL-POLAND:TWA 0.5 mg(V2O5)/m3 JAN 1993
OEL-SWEDEN:STEL 0.05 mg(V2O5)/m3 JAN 1993
OEL-SWEDEN:TWA 0.2 mg(V2O5)/m3 (dust) JAN 1993
OEL-SWITZERLAND:TWA 0.05 mg(V2O5)/m3;STEL 0.25 mg(V2O5)/m3 JAN 1993
OEL-TURKEY:TWA 0.5 mg(V2O5)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.05 mg(V2O5)/m3 (dust) JAN 1993
OEL-UNITED KINGDOM:TWA 0.5 mg(V2O5)/m3 JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO VANADIUM (as V2O5), resp dust/fume-air:CL 0.05 mg/m3/15M
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** END OF RECORD ***
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