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MSDS  : Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimid in)-3'-ol, 2',3'-dihydro-3'-phenyl- 1-(phenylmethyl)-, dihydrobromide
CAS  : 60856-20-4
SYNONYMS  :
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : WH1441000
CHEMICAL NAME : Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimid
in)-3'-ol, 2',3'-dihydro-3'-phenyl-
1-(phenylmethyl)-, dihydrobromide
CAS REGISTRY NUMBER : 60856-20-4
LAST UPDATED : 198511
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C23-H27-N3-O-S.2Br-H
MOLECULAR WEIGHT : 555.43
COMPOUND DESCRIPTOR : Drug

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 360 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
V.9- 1974- Volume(issue)/page/year: 11,115,1976

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
V.9- 1974- Volume(issue)/page/year: 11,115,1976

*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Spiro(naphthalene-1(2H),3'-pyrrolidine)-2',5'-dione,3,4-dihydro-1'-(4-piperidinobutyl)-, hydrochloride,(+-)- 74247-00-0
Spiro(naphthalene-1(2H),3'-pyrrolidine)-2',5'-dione,3,4-dihydro-1'-(3-piperidinopropyl)-, hydrochloride,(+-)- 74246-83-6
Spiro(naphthalene-1(2H),3'-pyrrolidine)-2',5'-dione,3,4-dihydro-1'-(4-(propylamino)butyl)-, (+-)- 74246-95-0
Spiro(naphthalene-1(2H),3'-pyrrolidine)-2',5'-dione,3,4-dihydro-1'-(4-(propylamino)butyl)- 7-methyl-,hydrochloride 76311-51-8
Spiro(naphthalene-1(2H),3'-pyrrolidine)-2',5'-dione,3,4-dihydro-1'-(4-(1-pyrrolidinyl) butyl)-,hydrochloride, (+-)- 74246-99-4
Spiro(naphthalene-1(2H),3'-pyrrolidine)-2',5'-dione,3,4-dihydro-1'-(3-(1-pyrrolidinyl) propyl)-,hydrochloride, (+-)- 74246-82-5
Spiro(indan-2,3'-pyrrolidine)-2',5'-dione,1'-(4-(dimethylamino)butyl)-, hydrochloride 74246-82-5
Spiro(1H-naphtho(2,3-C)pyran-1,2'-(2H)-pyran)-3-acetic acid, 4'-(acetyloxy)-3,3',4,4',5,5',6'10-octahydro-3',9-dihydroxy-6'-methyl-5,10-dioxo-,(2'S-(2'-alpha-(S*),3'-alpha,4'-alpha, 6'-beta))- 59554-12-0
Spiro(naphth(1,2-b)oxirene-5-(1aH),2'-oxiran)-3'-carboxaldehyde, 2,3,3a,4,6,7b-hexahydro-2-hydroxy-6-oxo-3,3',3a-trimethyl-,(1aR-(1a-alpha,2-beta,3-beta,3a-beta,5-beta(S*),7b-alpha))- 56326-21-7
Spiro(naphth(1,2-b)oxirene-5(1a-H),2'-oxirane)-2,6-diol, 2,3,3a,4,6,7b-hexahydro-3'-(hydroxymethyl)-3,3',3a-trimethyl-, 2-acetate 56326-23-9
Spiro(naphtho(2,3-c)thiophene-1(3H),2'-pyrrolidin)-3-one, 1'-methyl- 83962-57-6
Spiro(norbornane-2,5'-(2)oxazoline), 2'-amino- 25517-58-2
Spiro(norbornane-2,2'-thiophene),tetrahydro-4',4',5',5'-tetrafluoro- 25517-58-2
Spiro(1-alpha-H,5-alpha-H-nortropane-8,1'-pyrrolidinium), 3-alpha-hydroxy-, chloride, benzilate 10405-02-4
Spiro(6-oxabicyclo(3.1.0)hex-3-ene-2,2'-oxirane),4-isocyano-3'-methyl-, (1-alpha,2-beta(S*),(5-alpha)-(+)- 83016-48-2
Spiro(11-oxabicyclo(8.1.0)undec-6-ene-2,2'-oxiran)-3-one, 8-methylene-5-(1-methylethyl)-,(1R-(1R*,2R*,5S*,6E,10R*))- 61228-92-0
Spiro(oxazolidine-5,4'-piperidine),3,4-diethyl-1'-(1,2,3,4-tetrahydro-2-naphthyl)- 52109-31-6
Spiro(7H-indeno(4,5-d)-1,3-dioxole-7,1'(2'H)-isoquinolin)-6'-ol, 3',4',6,8-tetrahydro-7'-methoxy-2'-methyl-6-methylene-, (S)- 4959-88-0
Spiro(oxazolidine-5,4'-piperidine),4-ethyl-1'-(1,2,3,4-tetrahydro-2-naphthyl)-2-oxo- 29122-07-4
Spiro(oxirane-2,1'(2H)-pentaleno(1,6a-c)pyran)-5'-carboxylic acid, 4',4'a,6'a,7'-tetrahydro-7',8'-dimethyl-2'-oxo-,(1'R-(1'-alpha,4'a-alpha,6'a-beta,7'-alpha,9'aS*))- 31501-48-1
Spiro(oxirane-2,14'-(8-beta)podocarp(1)ene)-3-carboxylic acid, 13'-beta-(3-furylhydroxymethyl)-7'-alpha-hydroxy-8',13'-dimethyl-3'-oxo-, 3,13'-lactone, acetate 2629-11-0
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-((4-(3-chlorophenyl)-1-piperazinyl)acetyl)-1-(pheny lmethyl)- 130889-44-0
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-2'-(2-(4-(3-chlorophenyl)-1-piperazinyl)ethyl)-1-(phenylmethyl)- 130908-36-0
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-2'-(4-morpholinylacetyl)-1-(phenylmethyl)-, dihydrate 130908-35-9
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-2'-(2-(4-morpholinyl)ethyl)-1-(phenylmethyl)- 130889-47-3
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-1-(phenylmethyl)-2'-((4-phenyl-1-piperazinyl)acetyl)-, monohydrochloride 130880-61-4
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-1-(phenylmethyl)-2'-(2-(4-phenyl-1-piperazinyl)ethyl)- 132054-05-8
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-1-(phenylmethyl)-2'-(1-piperidinylacetyl)-, hydrate (2:1) 130908-34-8
Spiro(3H-indole-3,5'(5H)-pyrano(2,3-d)pyrimidine)-6'-carbonitrile, 1,1',2,2',3',4'-hexahydro-7'-amino-5-fluoro-2,2',4'-trioxo- 116719-49-4
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-1-(phenylmethyl)-2'-(2-(1-piperidinyl)ethyl)- 130889-46-2
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-1-(phenylmethyl)-2'-(1-pyrrolidinylacetyl)-, hydrate (2:1) 130889-42-8
Spiro(piperidine-4,1'-(1H)pyrido(3,4-b)indole),2',3',4',9'-tetrahydro-1-(phenylmethyl)-2'-(2-(1-pyrrolidinyl)ethyl)- 130889-45-1
Spiro(piperidine-4,1'-(1H)pyrido(4,3-b)indole),2',3',4',5'-tetrahydro-1,3',3'-trimethyl-,dihydrochloride 60948-04-1
Spiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one,1-(2-(3,4-dimethoxyphenyl)-2-hydroxyethyl)-3'-methyl- 85732-33-8
Spiro(piperidine-4,4'(1'H)-quinazolin)-2'(3'H)-one,1-(2-hydroxy-2-phenylethyl)-3'-methyl- 85732-32-7
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidine), 1-butyl-3'-(2-naphthalenyl)-, ethanedioate(1:2) 52419-76-8
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidine), 3'-(3,4-dichlorophenyl)-1-octyl-, ethanedioate(1:2) 60856-45-3
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-1-butyl-3'-(2,5-dimethoxyphenyl)-, dihydrobromide 52419-67-7
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-(3,4-dichlorophenyl)-1-(phenylmethyl)-,dihydrobromide 52419-71-3
Spiro(3H-indole-3,5'(5H)-pyrano(2,3-d)pyrimidine)-6'-carboxylic acid, 1,1',2,2',3',4'-hexahydro-7'-amino-5-fluoro-2,2',4'-trioxo-, ethylester 116743-81-8
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-(2,5-dimethoxyphenyl)-1-octyl-, dihydrobromide 52488-15-0
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-(2,5-dimethoxyphenyl)-1-(phenylmethyl)-,dihydrobromide 52419-70-2
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-(2-methoxyphenyl)-1-octyl-, dihydrobromide 52419-77-9
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-(2-methoxyphenyl)-1-(phenylmethyl)-,dihydrobromide 52501-97-0
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-(2-naphthalenyl)-1-(phenylmethyl)-, dihydrobromide 52419-69-9
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-1-(phenylmethyl)-3'-(5,6,7,8-tetrahydro-2-naphthalenyl)-, dihydrobromide 52419-72-4
Spiro(piperidine-4,6'(7'H)-(5H)thiazolo(3,2-a)pyrimidin)-3'-ol, 2',3'-dihydro-3'-phenyl-1-(phenylmethyl)-, dihydrobromide 60856-20-4
Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one,6'-chloro-4'-(2-fluorophenyl)- 112634-58-9
Spiro(quinuclidine-3,2'-thiazolidine),dihydrochloride 19039-24-8
Spirosta-5,25(27)-diene-1,3,11-triol(1-beta,3-beta,11-alpha)- 34302-29-9

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