*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CH7700000
CHEMICAL NAME : Arsine oxide, dimethylhydroxy-, sodium salt
CAS REGISTRY NUMBER : 124-65-2
LAST UPDATED : 199801
DATA ITEMS CITED : 32
MOLECULAR FORMULA : C2-H6-As-O2.Na
MOLECULAR WEIGHT : 159.99
WISWESSER LINE NOTATION : Q-AS-O&1&1 &-NA-
COMPOUND DESCRIPTOR : Agricultural Chemical
Drug
Organometallic
Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Alkarsodyl
* Ansar 160
* Ansar 560
* Arsecodile
* Arsicodile
* Arsinic acid, dimethyl-, sodium salt
* Arsycodile
* Bolls-eye
* Cacodylate de sodium
* Cacodylic acid sodium salt
* Chemaid
* Dimethylarsinat sodny
* ((Dimethylarsino)oxy)sodium-As-oxide
* Dutch-treat
* Hydroxydimethylarsine oxide, sodium salt
* Kakodylan dodny
* Phytar 560
* Rad-E-Cate
* Rad-E-Cate 16
* Rad-E-Cate 25
* Rad-E-Cate 35
* Sodium dimethylarsinate
* Sodium, ((dimethylarsino)oxy)-, As-oxide
* Sodium salt of cacodylic acid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada,
171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,70,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of
National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
Ont., Canada)
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD691-490
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - hamster
DOSE : 900 mg/kg
SEX/DURATION : female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
07094) V.1- 1966- Volume(issue)/page/year: 29,679,1982
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - hamster
DOSE : 900 mg/kg
SEX/DURATION : female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
07094) V.1- 1966- Volume(issue)/page/year: 29,679,1982
** MUTATION DATA **
TYPE OF TEST : Mutation in mammalian somatic cells
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 9 gm/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 386,279,1997
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
MSHA STANDARD-air:TWA 0.5 mg(As)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,16,1971
OSHA PEL (Gen Indu):8H TWA 0.5 mg(As)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 0.5 mg(As)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 0.5 mg(As)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 0.5 mg(As)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-ARAB Republic of Egypt:TWA 0.2 mg(As)/m3 JAN 1993
OEL-AUSTRALIA:TWA 0.05 mg(As)/m3;Carcinogen JAN 1993
OEL-BELGIUM:TWA 0.2 mg(As)/m3 JAN 1993
OEL-DENMARK:TWA 0.05 mg(As)/m3 JAN 1993
OEL-FINLAND;Carcinogen JAN 1993
OEL-FRANCE:TWA 0.2 mg(As)/m3 JAN 1993
OEL-HUNGARY:STEL 0.5 mg(As)/m3;Carcinogen JAN 1993
OEL-INDIA:TWA 0.2 mg(As)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.5 mg(As)/m3 JAN 1993
OEL-POLAND:TWA 0.3 mg(As)/m3 JAN 1993
OEL-SWEDEN:TWA 0.03 mg(As)/m3;Carcinogen JAN 1993
OEL-SWITZERLAND:TWA 0.1 mg(As)/m3;Carcinogen JAN 1993
OEL-THAILAND:TWA 0.5 mg(As)/m3 JAN 1993
OEL-TURKEY:TWA 0.5 mg(As)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.2 mg(As)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84721
No. of Facilities: 34 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 136 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84721
No. of Facilities: 46 (estimated)
No. of Industries: 1
No. of Occupations: 3
No. of Employees: 185 (estimated)
No. of Female Employees: 168 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Arsine, (p-nitrophenyl)oxo-
| 3134-97-2 |
Arsine oxide, allylhydroxyphenyl-
| 21905-27-1 |
Antibiotic SF-1999
| 21905-27-1 |
Antibiotic U-60,394
| 76416-99-4 |
Arsine oxide, (3-amino-4-(2-hydroxyethoxy)phenyl)-
| 64048-94-8 |
Arsine oxide, butylhydroxyisopropyl-
| 73791-40-9 |
Arsine oxide,(o-chlorophenyl)(3-(2,4-dichlorophenoxy)-2-hydroxypropyl)hydroxy-
| 73791-41-0 |
Arsine oxide,(m-chlorophenyl)hydroxy(beta-hydroxyphenethyl)-
| 21905-40-8 |
Arsine oxide, (p-chlorophenyl)hydroxymethyl-
| 73791-42-1 |
Arsine oxide, 2-chlorovinyl-
| 3088-37-7 |
Arsine oxide, dibutylhydroxy-
| 2850-61-5 |
Arsine oxide, dichloro(2-chlorovinyl)-
| 333-25-5 |
Arsine oxide, diethylhydroxy-
| 4964-27-6 |
Arsine oxide, dimethylhydroxy-
| 75-60-5 |
Antibiotic V28-3M
| 121127-08-0 |
Arsine oxide, dimethylhydroxy-, sodium salt
| 124-65-2 |
Arsine oxide, diphenylhydroxy-, nitrate
| 64048-95-9 |
Arsine oxide, hydroxydimethyl-, sodium salt,trihydrate
| 6131-99-3 |
Arsine oxide, hydroxydiphenyl-
| 4656-80-8 |
Arsine oxide, hydroxy(2-hydroxypropyl)phenyl-
| 21905-32-8 |
Arsine oxide, hydroxyisobutylisopropyl-
| 73791-43-2 |
Arsine oxide, hydroxymethylphenethyl-
| 73791-44-3 |
Arsine oxide, hydroxymethylphenyl-
| 13911-65-4 |
Arsine oxide, hydroxymethylpropyl-
| 73791-45-4 |
Arsine oxide, trimethyl-
| 4964-14-1 |
Antibiotic W-2SUBSTANCE DEFINITION :Isolated from Streptomyces diastatochromogenesREFERENCE :85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., BocaRaton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,295,1980
| 4964-14-1 |
Arsine, oxophenyl-
| 637-03-6 |
Arsine, oxo-m-tolyl-
| 637-03-6 |
Arsine, oxo-o-tolyl-
| 637-03-6 |
Arsine, oxo-p-tolyl-
| 637-03-6 |
Arsine, oxybis(dimethyl-
| 503-80-0 |
Arsine, oxybis(diphenyl-
| 2215-16-9 |
Arsine, pentyldibromo-
| 64047-02-5 |
Arsine selenide, trimethyl-
| 41262-21-9 |
Arsine sulfide, dimethyldi-
| 13367-92-5 |
Arsine, tricyclohexyl-
| 23356-03-8 |
Antibiotic WR142-fpg
| 66240-89-9 |
Arsine, tri-2-furyl-
| 64048-96-0 |
Arsine, trimethyl-
| 593-88-4 |
Arsine, trioctyl-
| 64048-97-1 |
Arsine, triphenyl-
| 603-32-7 |
Arsine, tri-2-pyridyl-
| 603-32-7 |
Arsine, tris(dimethyldithiocarbamoyl)-
| 3586-60-5 |
Arsine, tris(3,3,5-trimethylcyclohexyl)-
| 64048-98-2 |
Arsine, tri-2-thienyl-
| 64048-98-2 |
Arsinous amide,N,N-dimethyl-As-ethyl-As-(2-methoxyphenyl)-
| 61130-99-2 |
Arsinous amide, N,N-dimethyl-As-ethyl-As-phenyl-
| 61130-96-9 |
Antibiotic, WS-7528SUBSTANCE DEFINITION :Isolated from Streptomyces sp. no. 7528REFERENCE :JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-Volume(issue)/page/year: 43,1394,1990
| 61130-96-9 |
Arsinous amide, As-(2-methylphenyl)-As,N,N-triethyl-
| 61131-18-8 |
Arsinous amide, As-(4-methylphenyl)-As,N,N-triethyl-
| 61131-20-2 |
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