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 Arsenic chloride
CAS  
:
 7784-34-1
SYNONYMS  
:
 * Arsenic butter
* Arsenic(III) chloride
* Arsenous chloride
* Arsenous trichloride
* Butter of arsenic
* Chlorure arsenieux
* Chlorure d'arsenic
* Fuming liquid arsenic
* Trichloroarsine
* Trichlorure d'arsenic

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                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CG1750000
CHEMICAL NAME           : Arsenic chloride
CAS REGISTRY NUMBER     : 7784-34-1
LAST UPDATED            : 199712
DATA ITEMS CITED        : 36
MOLECULAR FORMULA       : As-Cl3
MOLECULAR WEIGHT        : 181.27
WISWESSER LINE NOTATION :  AS  G3
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Arsenic butter
   * Arsenic(III) chloride
   * Arsenous chloride
   * Arsenous trichloride
   * Butter of arsenic
   * Chlorure arsenieux
   * Chlorure d'arsenic
   * Fuming liquid arsenic
   * Trichloroarsine
   * Trichlorure d'arsenic
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 27(4),54,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 27(4),54,1983
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 338 ppm/10M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 1,324,1955
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 200 mg/m3/20M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 1,324,1955
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 50 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 31,185,1975
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 600 nmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 88,73,1981
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 5500 ug/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 389,3,1997
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 3 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,193,1979

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.01 mg(As)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Confirmed human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.5 mg(As)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,16,1971

   OSHA-cancer hazard
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1018,1987

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.2 mg(As)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.05 mg(As)/m3;Carcinogen JAN 1993
   
   OEL-BELGIUM:TWA 0.2 mg(As)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.05 mg(As)/m3 JAN 1993
   
   OEL-FINLAND;Carcinogen JAN 1993
   
   OEL-FRANCE:TWA 0.2 mg(As)/m3 JAN 1993
   
   OEL-HUNGARY:STEL 0.5 mg(As)/m3;Carcinogen JAN 1993
   
   OEL-INDIA:TWA 0.2 mg(As)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.5 mg(As)/m3 JAN 1993
   
   OEL-POLAND:TWA 0.3 mg(As)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.03 mg(As)/m3;Carcinogen JAN 1993
   
   OEL-SWITZERLAND:TWA 0.1 mg(As)/m3;Carcinogen JAN 1993
   
   OEL-THAILAND:TWA 0.5 mg(As)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.5 mg(As)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.2 mg(As)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO ARSENIC, INORGANIC-air:CA CL 0.002 mg(As)/m3/15M
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 82192
       No. of Facilities: 139 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 823 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 82192
       No. of Facilities: 36 (estimated)
       No. of Industries: 3
       No. of Occupations: 3
       No. of Employees: 1142 (estimated)
       No. of Female Employees: 152 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Cell transform.-SA7/SHE; B subtilis rec
   assay
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH CURRENT INTELLIGENCE BULLETIN 14, 1976

 
                            *** END OF RECORD ***
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NAMECAS
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m-Arsanilic acid, 4-methyl-, disodium salt 6318-57-6
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Arsanilic acid, monosodium salt, pentahydrate 127-85-5
Arsanilic acid, monosodium salt, tetrahydrate 6696-54-4
p-Arsanilic acid,N-(3-(5-nitrofurfurylidene)carbazoyl)- 6696-54-4
Arsanilic acid,N-(3-(5-nitrofurfurylidene)carbazoyl)-, sodium salt 6696-54-4
Arsanilic acid, N-3-phenoselenazinyl- 64047-00-3
Antibiotic T 36496 57107-63-8
Arsenenic acid, sodium salt 15120-17-9
Arsenenous acid, calcium salt (21) 15194-98-6
Arsenic acid (HAsO2), potassium salt 13464-35-2
Arsenic 7440-38-2
Arsenic acid (H3AsO4) 7778-39-4
Arsenic acid, (O3-As-H) 10102-53-1
Arsenic acid, ammonium magnesium salt, hydrate(1:1:1:2) 14644-70-3
Arsenic acid, calcium salt 10103-62-5
Arsenic acid, calcium salt (11) 15195-00-3
Arsenic acid, calcium salt (23) 7778-44-1
Antibiotic T-42318 68072-82-2
Arsenic acid, calcium salt, hydrate (233) 68072-82-2
Arsenic acid, copper(2+) salt (23), tetrahydrate 13478-34-7
Arsenic acid, diammonium salt 7784-44-3
Arsenic acid, disodium salt 7778-43-0
Arsenic acid, disodium salt, heptahydrate 10048-95-0
Arsenic acid, hemihydrate 7774-41-6
Arsenic acid, iron salt, pentahydrate 7774-41-6
Arsenic acid, lead salt 7645-25-2
Arsenic acid, lead(2+) salt 13464-43-2
Arsenic acid, lead(2+) salt(11) 7784-40-9
Antibiotic T 47811 72067-80-2
Arsenic acid, lead(2+) salt (23) 3687-31-8
Arsenic acid, magnesium salt 10103-50-1
Arsenic acid, magnesium salt (16) 12255-72-0
Arsenic acid, manganese(2+) salt, hydrate (236) 61136-68-3
Arsenic acid, monopotassium salt 7784-41-0
Arsenic acid, monosodium salt 10103-60-3
Arsenic acid, sodium salt 7631-89-2
Arsenic acid, tricesium salt 61136-62-7
Arsenic acid, trisodium salt 13464-38-5
Arsenic(V) acid, trisodium salt, heptahydrate (137) 64070-83-3
Antibiotic SF 1990 68053-07-6
Antibiotic Ta-146 62563-39-7
Arsenical dip 8028-75-9
Arsenical dust 8028-73-7
Arsenic(II) bromide 7784-33-0
Arsenic chloride 7784-34-1
Arsenic iodide 7784-45-4
Arsenic pentoxide 1303-28-2
Arsenic selenide 1303-36-2

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