*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : XH4900000
CHEMICAL NAME : Theophylline,
8-benzyl-7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)-,
monohydrochloride
CAS REGISTRY NUMBER : 20684-06-4
LAST UPDATED : 199706
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C20-H27-N5-O3.Cl-H
MOLECULAR WEIGHT : 421.98
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ B2N2&2Q C1R& F1 H1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* AC 3810
* Bamifylline hydrochloride
* Bamiphylline hydrochloride
* BAX 2793Z
* 8-Benzyl-7-(N-ethyl-N-(beta-hydroxyethyl)aminoethyl)theophylline
hydrochloride
* 8'-Benzyl-7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)theophylline
hydrochloride
* Benzetamophylline hydrochloride
* 8102 CB hydrochloride
* 7-(N-(beta-Hydroxyethyl)-N-ethyl)-aminoethyl-8-benzyl-theophylline
hydrochloride
* Trentadil
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1139 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 131 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 64800 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 246 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 89400 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 66800 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 614 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 28800 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 165 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 18,460,1968
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Theobromine, 8-(propylthio)-
| 74039-58-0 |
Theobromine, sodium salt
| 1010-59-9 |
Tetrazolo(1,5-b)pyridazine,6-(4-chlorophenyl)-8-phenyl-
| 130216-52-3 |
Theoesberiven
| 65098-93-3 |
Theonella swinhoei, extractSUBSTANCE DEFINITION :Extracted from a marine spongeREFERENCE :TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,UK) V.1- 1962- Volume(issue)/page/year: 23,955,1985
| 65098-93-3 |
Theophylline
| 58-55-9 |
7-Theophyllineacetamide, oxime, hydrochloride
| 74039-59-1 |
Theophylline-8-acetic acid
| 5439-51-0 |
Theophylline, 8-(acetonylthio)-6-thio-
| 6466-01-9 |
Theophylline, 7-(acetylmethyl)-8-morpholino-,hydrochloride
| 74039-60-4 |
Theophylline, 7-(acetylmethyl)-8-(1-piperazinyl)-,hydrochloride
| 74039-61-5 |
Theophylline, 7-allyl-
| 61444-26-6 |
Theophylline, 8-allyl-
| 74039-62-6 |
Tetrazolo(1,5-b)pyridazine, 6,8-diphenyl-
| 130187-50-7 |
Theophylline, 8-allylamino-7-(2,3-dihydroxypropyl)-
| 78960-43-7 |
Theophylline, 7-allyl-8-hydrazino-
| 19800-66-9 |
Theophylline,7-allyl-8-(1-(2-hydroxyethyl)hydrazino)-
| 19800-79-4 |
Theophylline, 7-allyl-8-(1-methylhydrazino)-
| 19800-76-1 |
Theophylline, 7-(3-(4-allyl-1-piperazinyl)propyl)-,dihydrochloride
| 23237-83-4 |
Theophylline, 8-allylthio-6-thio-
| 6493-39-6 |
Theophylline, 8-amino-
| 19410-53-8 |
Theophylline, 8-amino-7-(2-(diethylamino)ethyl)-,monohydrochloride
| 19410-53-8 |
Theophylline, compd. with 2-aminoethanol (11)
| 573-41-1 |
Theophylline, compd. with 2-aminoethanol (12)
| 5967-82-8 |
Tetrazolo(1,5-b)pyridazine,6-(4-fluorophenyl)-8-phenyl-
| 130430-76-1 |
Theophylline, 7-(2-aminoethyl)-
| 35206-02-1 |
Theophylline, 8-((2-aminoethyl)amino)-
| 14251-32-2 |
Theophylline, 7-(2-((2-aminoethyl)amino)ethyl)-,hydrochloride
| 14251-32-2 |
Theophylline, 8-(2-aminoethyl)thio-6-thio-
| 6559-88-2 |
Theophylline, compd. with 2-amino-2-methyl-1-propanol(1:1)
| 5634-34-4 |
Theophylline, 7-(2-(aminooxy)ethyl)-,monohydrochloride
| 59663-16-0 |
Theophylline, 7-(3-(aminooxy)propyl)-,monohydrochloride
| 59663-17-1 |
Theophylline, 7-(3-aminopropyl)-8-(3-pyridylmethyl)-,monohydrochloride
| 30825-03-7 |
Theophylline, 8-amino-, sodium salt
| 30825-03-7 |
Theophylline, 8-anilino-7-(2,3-dihydroxypropyl)-
| 78960-47-1 |
Teucrium Oliverianum, leaf, stem, root extractSUBSTANCE DEFINITION :Plant belonging to the family LabiataeREFERENCE :YAHOA3 Yakhak Hoe Chi. Journal of the Pharmaceutical Society. (TaehanYakkakhoe, c/o College of Pharmacy, Seoul National Univ., Seoul 151, S.Korea) V.1- 1956(?)- Volume(issue)/page/year: 21,141,1977
| 78960-47-1 |
Theophylline, 8-(4-(2-benzimidazolyl)butyl)-
| 74039-64-8 |
Theophylline, 7-benzyl-
| 1807-85-8 |
Theophylline, 8-benzyl-
| 2879-15-4 |
Theophylline, 7-(2-(benzylamino)ethyl)-,hydrochloride
| 1236-36-8 |
Theophylline,8-(benzylamino)-7-(2-hydroxy-3-(4-benzyl-1-piperazinyl)propyl)-, dihydrochloride
| 105319-52-6 |
Theophylline,8-(benzylamino)-7-(2-hydroxy-3-(4-(2-hydroxypropyl)-1-piperazinyl)propyl)-, dihydrochloride
| 105319-54-8 |
Theophylline,8-(benzylamino)-7-(2-hydroxy-3-(4-methyl-1-piperazinyl)propyl)-, dihydrochloride
| 105319-55-9 |
Theophylline,8-benzyl-7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)-,monohydrochloride
| 20684-06-4 |
Theophylline,8-benzyl-7-(1'-morpholino-2'-amino)ethyl-,hydrochloride
| 63906-64-9 |
Theophylline, 7-(2-(4-benzyl-1-piperazinyl)ethyl)-
| 19971-87-0 |
Teucrium Oliverianum R. Br., extract
| 19971-87-0 |
Theophylline, 7-(3-(4-benzyl-1-piperazinyl)propyl)-,dihydrochloride
| 19971-75-6 |
Theophylline, 7-(2-(benzylsulfinyl)ethyl)-
| 3810-41-1 |
Theophylline, 7-butyl-
| 1021-65-4 |
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