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MSDS  : Toxin, nematocyst, physalia physalis
CAS  : 54992-19-7
SYNONYMS  : * Physalia physalis toxin * Portuguese man-of-war toxin * P. physalis toxin
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : XW5868200
CHEMICAL NAME : Toxin, nematocyst, physalia physalis
LAST UPDATED : 198611
DATA ITEMS CITED : 5
COMPOUND DESCRIPTOR : Natural Product
SYNONYMS/TRADE NAMES :
* Physalia physalis toxin
* Portuguese man-of-war toxin
* P. physalis toxin

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 4,199,1966

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 37 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - changes in motor activity (specific assay)
Behavioral - ataxia
REFERENCE :
BIBUBX Biological Bulletin (Woods Hole, Massachusetts). (Marine Biological
Laboratories, Woods Hole, MA 02543) V.1- 1898- Volume(issue)/page/year:
115,219,1958

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2100 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - other changes
REFERENCE :
BIBUBX Biological Bulletin (Woods Hole, Massachusetts). (Marine Biological
Laboratories, Woods Hole, MA 02543) V.1- 1898- Volume(issue)/page/year:
115,219,1958

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 750 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 6,281,1969

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Amphibian - frog
DOSE/DURATION : 15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
23EIAT "Venomous Animals and Their Venoms," Buecherl, W., and E.E. Buckley,
eds., 3 vols., New York, Academic Press, Inc., 1968-71
Volume(issue)/page/year: 3,395,1971

*** END OF RECORD ***
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