RTECS NUMBER : XR1700000
CHEMICAL NAME : Titanium
CAS REGISTRY NUMBER : 7440-32-6
LAST UPDATED : 199710
DATA ITEMS CITED : 12
MOLECULAR FORMULA : Ti
MOLECULAR WEIGHT : 47.90
WISWESSER LINE NOTATION : .TI
COMPOUND DESCRIPTOR : Tumorigen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Contimet 30
* C.P. titanium
* IMI 115
* NCI-C04251
* Oremet
* T 40
* Titanate
* Titanium 50A
* Titanium alloy
* VT 1
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 114 mg/kg/77W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
Tumorigenic - tumors at site of application
REFERENCE :
NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the
National Cancer Institute by The Institute of Chemical Biology, University
of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year:
PH43-64-886
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 360 mg/kg/69W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
Tumorigenic - tumors at site of application
REFERENCE :
NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the
National Cancer Institute by The Institute of Chemical Biology, University
of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year:
PH43-64-886
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 158 mg/kg
SEX/DURATION : multigeneration
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St.,
NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year:
23,102,1971
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 73255
No. of Facilities: 1060 (estimated)
No. of Industries: 36
No. of Occupations: 42
No. of Employees: 21978 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X5095
No. of Facilities: 9 (estimated)
No. of Industries: 2
No. of Occupations: 5
No. of Employees: 250 (estimated)
No. of Female Employees: 53 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X5916
No. of Facilities: 6 (estimated)
No. of Industries: 2
No. of Occupations: 2
No. of Employees: 1198 (estimated)
No. of Female Employees: 400 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 73255
No. of Facilities: 11591 (estimated)
No. of Industries: 113
No. of Occupations: 97
No. of Employees: 189763 (estimated)
No. of Female Employees: 9744 (estimated)