RTECS NUMBER : YM5600000
CHEMICAL NAME : 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, mandelate
(ester)
CAS REGISTRY NUMBER : 87-00-3
BEILSTEIN REFERENCE NO. : 0087959
REFERENCE : 5-21-01-00234 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C16-H21-N-O3
MOLECULAR WEIGHT : 275.38
WISWESSER LINE NOTATION : T56 A ANTJ A1 GOVYQR
SYNONYMS/TRADE NAMES :
* Homatropin
* Homatropine
* Homoatropine
* Homotropine
* Mandelic acid, 3d-tropanyl ester
* Mandelyltropeine
* Mandelytropeine
* Tropine, mandelate (ester)
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
1,156,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1307 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2035763
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 370 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2035763
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2035763
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84350
No. of Facilities: 170 (estimated)
No. of Industries: 1
No. of Occupations: 6
No. of Employees: 2582 (estimated)
*** END OF RECORD ***
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