*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : ZH6500000
CHEMICAL NAME : Zinostatin stimalamer
CAS REGISTRY NUMBER : 123760-07-6
LAST UPDATED : 199506
DATA ITEMS CITED : 6
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Neocarzostatin, conjugate with styrene maleic acid anhydride copolymer
* Smancs
* YM 881
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3440 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment
Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948-
Volume(issue)/page/year: 54,2367,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
Volume(issue)/page/year: 80,394,1989
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4630 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment
Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948-
Volume(issue)/page/year: 54,2367,1984
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2800 ug/kg/4W-I
TOXIC EFFECTS :
Endocrine - changes in spleen weight
Blood - normocytic anemia
Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu
Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
Volume(issue)/page/year: 19,707,1991
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 840 ug/kg/4W-I
TOXIC EFFECTS :
Blood - changes in bone marrow (not otherwise specified)
Blood - changes in leukocyte (WBC) count
Blood - changes in platelet count
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu
Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-
Volume(issue)/page/year: 19,729,1991
** MUTATION DATA **
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - rat Lymphocyte
DOSE/DURATION : 2500 ug/L
REFERENCE :
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75,
1907-84. For publisher information, see JJCREP. Volume(issue)/page/year:
73,278,1982
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
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Zinc stearate
| 557-05-1 |
Zinc sulfate (11)
| 7733-02-0 |
Zinc sulfate, dihydrate
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Zinc sulfate heptahydrate (117)
| 7446-20-0 |
Zinc sulfide
| 1314-98-3 |
Venom, wasp, Vespula maculifrons
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Zinc trifluorostannite, heptahydrate
| 102916-22-3 |
Zinc(2+), tris(octamethylpyrophosphoramide)-,diperchlorate
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Zingiber capitatum Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family ZingiberaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
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| 15713-67-4 |
Zingiber mioga Rosc., extract
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Zingiber officinale Rosc., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family ZingiberaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 15713-67-4 |
Zingiber officinale Roscoe, rhizome extractSUBSTANCE DEFINITION :Plant belonging to the family ZingiberaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 15713-67-4 |
Zingiber roseum (roxb.) Rosc., extractSUBSTANCE DEFINITION :Plant belonging to the family ZingiberaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 15713-67-4 |
Zingiber roseum Rosc., stem extractSUBSTANCE DEFINITION :Plant belonging to the family ZingiberaceaeREFERENCE :INDRBA Indian Drugs. (Indian Drugs Manufacturers' Assoc., 102B, PoonamChambers, Dr. A. B. Rd., Worli, Bombay 400 018, India) V.1- 1963-Volume(issue)/page/year: 30,19,1993
| 15713-67-4 |
Zingiber zerumbet (Linn.) Sm., extractSUBSTANCE DEFINITION :Plant belonging to the family ZingiberaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 15713-67-4 |
Venom, wasp, Vespula pensylvanica
| 15713-67-4 |
Zinnia elegans Jacq., extractSUBSTANCE DEFINITION :Plant belonging to the family AsteraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,487,1984
| 15713-67-4 |
Zinostatin stimalamer
| 123760-07-6 |
Zirconate(2-), hexafluoro-, dipotassium
| 16923-95-8 |
Zirconium
| 7440-67-7 |
Zirconium, bis(acetato-O,O')oxo-
| 20645-04-9 |
Zirconium, bis(nitrato-O)oxo-
| 13826-66-9 |
Zirconium(IV) chloride (14)
| 10026-11-6 |
Zirconium chloride hydroxide
| 10119-31-0 |
Zirconium chloride oxide octahydrate
| 13520-92-8 |
Zirconium, dichloro-di-pi-cyclopentadienyl-
| 1291-32-3 |
VenoplantSUBSTANCE DEFINITION :Extracted from horse-chestnut seedsREFERENCE :NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,Japan) Volume(issue)/page/year: 6,758,1982
| 1291-32-3 |
Zirconium, dichlorooxo-
| 7699-43-6 |
Zirconium fluoride
| 7783-64-4 |
Zirconium gluconate
| 70983-41-4 |
Zirconium glutamate
| 70983-41-4 |
Zirconium hydride
| 7704-99-6 |
Zirconium(III) lactate (13)
| 63919-14-2 |
Zirconium(IV) lactate (14)
| 60676-90-6 |
Zirconium nitrate
| 13746-89-9 |
Zirconium oxide
| 1314-23-4 |
Zirconium(IV) silicate (11)
| 14940-68-2 |
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Zirconium sodium lactate
| 63904-82-5 |
Zirconium(IV) sulfate (12)
| 14644-61-2 |
Zirconium, tetrakis(2,4-pentanedionato-O,O')-
| 17501-44-9 |
Zirconyl citrate
| 22830-18-8 |
Zirconyl sodium citrate
| 22830-18-8 |
Zirconyl sodium gluconate
| 22830-18-8 |
Zirconyl sodium sulphate
| 24735-35-1 |
ZizaninSUBSTANCE DEFINITION :Produced by Helminthosporium zizaniaeREFERENCE :JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67.For publisher information, see JANTAJ. Volume(issue)/page/year: 15,88,1962
| 24735-35-1 |
Ziziphora taurica ssp. cleonioides, essential oil
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Ziziphora taurica ssp. taurica, essential oil
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| 24735-35-1 |
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