Search   
MSDS  : Xanthine, 3-hydroxy-
CAS  : 13479-29-3
SYNONYMS  : * 3-Hydroxyxanthine * 1H-Purine-2,6-dione, 3,7-dihydro-3-hydroxy- * Xanthine-x-N-oxide * Xanthine-3-N-oxide
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : ZD8100000
CHEMICAL NAME : Xanthine, 3-hydroxy-
CAS REGISTRY NUMBER : 13479-29-3
LAST UPDATED : 199109
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C5-H4-N4-O3
MOLECULAR WEIGHT : 168.13
WISWESSER LINE NOTATION : T56 BM DN FNVMVJ FQ
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* 3-Hydroxyxanthine
* 1H-Purine-2,6-dione, 3,7-dihydro-3-hydroxy-
* Xanthine-x-N-oxide
* Xanthine-3-N-oxide

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARPAAQ Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50;
V.70-99, 1960-75. For publisher information, see APLMAS.
Volume(issue)/page/year: 86,395,1968

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 770 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
30,179,1970

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 500 mg/kg
female 19-22 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
Liver - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC)
V.61-79, 1978-87. For publisher information, see JNCIEQ.
Volume(issue)/page/year: 61,1405,1978

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 96 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Liver - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
38,2038,1978

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 9600 ug/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
38,2038,1978

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 500 mg/kg
female 19-22 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
Skin and Appendages - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC)
V.61-79, 1978-87. For publisher information, see JNCIEQ.
Volume(issue)/page/year: 61,1411,1978

TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 96 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
38,2038,1978

** MUTATION DATA **

TYPE OF TEST : DNA damage
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 50 mg/kg
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year:
10,19,1975

*** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Venom, spider, Grammostola mollicoma 58741-69-8
Xanthen-9-one, 3-isopropoxy-4-(1-pyrrolidinyl)methyl- 58741-68-7
Xanthen-9-one, 3-methoxy-4-(morpholinomethyl)-,hydrochloride 17854-77-2
Xanthen-9-one, 4-methoxy-3-morpholinomethyl-,hydrochloride 42840-08-4
9H-Xanthen-9-one, 3-methoxy-4-(4-morpholinylmethyl)- 17862-45-2
Xanthen-9-one, 3-methoxy-2-(piperidinomethyl)-,hydrochloride 17862-45-2
Xanthen-9-one, 3-methoxy-4-(piperidinomethyl)-,hydrochloride 17854-76-1
Xanthen-9-one, 4-methoxy-3-piperidinomethyl-,hydrochloride 42840-07-3
Xanthen-9-one, 3-methoxy-4-(3-piperidinopropenyl)-,hydrochloride 42840-07-3
9H-Xanthen-9-one, 3-methoxy-4-(1-piperidinylmethyl)- 17854-59-0
Xanthen-9-one, 3-methoxy-4-(1-pyrrolidinylmethyl)-,hydrochloride 17854-59-0
Venom, spider, Grammostola pulchripes 17854-59-0
Xanthen-9-one, 4-methoxy-3-pyrrolidinylmethyl-,hydrochloride 42840-09-5
Xanthen-9-one, 3-methoxy-1,5,8-trihydroxy- 2798-25-6
Xanthen-9-one, 6-methoxy-1,2,8-trihydroxy- 20882-75-1
Xanthen-9-one, 4-morpholinomethyl-, hydrochloride 29242-22-6
Xanthen-9-one, 4-morpholinomethyl-3-nitro- 43159-94-0
Xanthen-9-one, 3-nitro-4-piperidinomethyl- 43159-93-9
Xanthen-9-one, 3-nitro-4-pyrrolidinylmethyl- 43159-95-1
Xanthen-9-one, 4-piperidinomethyl-, hydrochloride 29312-75-2
Xanthen-9-one, 4-pyrrolidinylmethyl-, hydrochloride 29242-19-1
Xanthen-9-one, 1,2,6,8-tetrahydroxy- 22172-15-2
Venom, spider, Heteropoda venatoria 22172-15-2
Xanthen-9-one, 1,3,5,8-tetrahydroxy- 2980-32-7
Xanthen-9-one, 1,3,7-trihydroxy- 529-49-7
Xanthen-9-one, 1,3,7-trimethoxy- 3722-54-1
Xanthic acid, butyl-, ester with mercaptoacetic acid,calcium salt 64038-47-7
Xanthicin 102583-69-7
Xanthine 69-89-6
Xanthine, 3-allyl-1-ethyl-6-thio-, sodium salt 69-89-6
Xanthine, 1-allyl-3-phenyl-, sodium salt 69-89-6
Xanthine, 1-butyl-3-methyl-, sodium salt 69-89-6
Xanthine, 3-butyl-7-methyl-6-thio-, sodium salt 69-89-6
Venom, spider, Lasiodora klugi 69-89-6
Xanthine, 8-(butylthio)- 73840-28-5
Xanthine, 1,3-dibutyl-6-thio-, sodium salt 73840-28-5
Xanthine, 1-(2,3-dihydroxypropyl)-3-methyl- 120267-26-7
Xanthine, 1,9-dimethyl-3-(2-hydroxyethyl)- 87866-16-8
Xanthine, 1,8-dimethyl-3-phenyl- 72702-76-2
Xanthine, 1-ethyl-3-isobutyl-, sodium salt 72702-76-2
Xanthine, 1-ethyl-3-isobutyl-6-thio-, sodium salt 72702-76-2
Xanthine, 8-(ethylthio)- 73840-29-6
Xanthine, 3-furfuryl-1-methyl-, sodium salt 73840-29-6
Xanthine, 3-furfuryl-1-methyl-6-thio-, sodium salt 73840-29-6
Venom, spider, Latrodectus bishopi 73840-29-6
Xanthine, 8-(heptylthio)- 73840-30-9
Xanthine, 3-hydroxy- 13479-29-3
Xanthine, 3-hydroxy-, acetate 22052-01-3
Xanthine, 1-hydroxy-, dihydrate 64038-48-8
Xanthine, 7-(2-hydroxyethoxy)-1,3,8-trimethyl- 19774-85-7

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com| Ads link:todaystock.net