Veratrum californicum
SUBSTANCE DEFINITION :
Top (plant) material from Veratrum californicum (durand)
REFERENCE :
CJBIAE Canadian Journal of Biochemistry. (Ontario, Canada) V.42-60,
1964-82. For publisher information, see CJBBDU.
RTECS NUMBER : YX7140000
CHEMICAL NAME : Veratrum californicum
SUBSTANCE DEFINITION :
Top (plant) material from Veratrum californicum (durand)
REFERENCE :
CJBIAE Canadian Journal of Biochemistry. (Ontario, Canada) V.42-60,
1964-82. For publisher information, see CJBBDU.
LAST UPDATED : 199506
DATA ITEMS CITED : 4
COMPOUND DESCRIPTOR : Reproductive Effector
Natural Product
SYNONYMS/TRADE NAMES :
* False hellebore
* Skunk cabbage
* Western hellebore
* Wild corn
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 900 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Lungs, Thorax, or Respiration - dyspnea
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
AFECAT Annales des Falsifications et de l'Expertise Chimique. (Paris,
France) V.53, No.613-No.779, 1960-79. Volume(issue)/page/year:
76(815),65,1983
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE/DURATION : 15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMZOAF American Zoologist. (American Soc. of Zoologists, Box 2739,
California Lutheran College, Thousand Oaks, CA 91360) V.1- 1961-
Volume(issue)/page/year: 9,1134,1969
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - domestic
DOSE : 236 gm/kg
SEX/DURATION : female 1-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
AJVRAH American Journal of Veterinary Research. (American Veterinary
Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940-
Volume(issue)/page/year: 24,1164,1963
*** REVIEWS ***
TOXICOLOGY REVIEW
AEMBAP Advances in Experimental Medicine and Biology. (Plenum Pub. Corp.,
233 Spring St., New York, NY 10013) V.1- 1967- Volume(issue)/page/year:
27,107,1972
*** END OF RECORD ***
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