*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : ZC7900000
CHEMICAL NAME : Withania ashwagandha, Kaul, alkaloid extract
LAST UPDATED : 199304
DATA ITEMS CITED : 8
COMPOUND DESCRIPTOR : Drug
Natural Product
SYNONYMS/TRADE NAMES :
* Shwagandholine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >4500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 4,35,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 465 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 9,127,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 432 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 9,127,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 582 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - other changes
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 4,35,1960
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : >1400 mg/kg
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of salivary glands
Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 4,35,1960
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Intraduodenal
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : >700 mg/kg
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of salivary glands
Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 4,35,1960
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : >1400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 4,35,1960
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute
of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
India) V.1- 1957- Volume(issue)/page/year: 4,35,1960
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Wendlandia heynei Sant. & Merch., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 9,91,1971
| 74686-30-9 |
Wendlandia notoniana Wall., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 74686-30-9 |
Wendlandia puberula DC., extract excluding rootSUBSTANCE DEFINITION :Indian plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 74686-30-9 |
Wendlandia tinctoria DC., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 74686-30-9 |
Wendlandia wallichii Wight & Arn., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
| 74686-30-9 |
Venom, snake, Vipera xanthina palaestinae
| 74686-30-9 |
Weston 439
| 93356-94-6 |
Wheat, extract
| 93356-94-6 |
Wheat flour lipids, chlorinatedSUBSTANCE DEFINITION :Extracted from cake flour by soxhlet extraction with diethylether, andchlorinated by bubbling Cl2 through yielding 18.4% Cl2 by weightREFERENCE :NURIBL Nutrition Reports International. (Geron-X, Inc., POB 1108, LosAltos, CA 94022) V.1- 1970- Volume(issue)/page/year: 16,11,1977
| 93356-94-6 |
White Spirit
| 93356-94-6 |
White spirit, dilutine 5
| 93356-94-6 |
Wikstroemia canescens Meissn., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family ThymelaeaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 93356-94-6 |
Wikstroemia chamaedaphne Meissn., total flavanoids
| 93356-94-6 |
Wikstroemia indica (linn.) C. A. Mey, extractexcluding roots
| 92129-95-8 |
Wikstroemia indica (linn.) C.A. Mey, root extract
| 92129-95-8 |
Win 42122-2
| 74191-35-8 |
Venom, snake, Trimeresurus flavoviridis
| 74191-35-8 |
Venom, snake, Walterinnesia aegyptia
| 74191-35-8 |
WIN 42122-2, sulfate (salt)
| 74339-35-8 |
Wisteria chinensis DC. extract excluding rootSUBSTANCE DEFINITION :Indian plant belonging to the family FabaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 74339-35-8 |
Witepsol E-75
| 56749-17-8 |
Withania ashwagandha, Kaul, alkaloid extract
| 56749-17-8 |
Withania Somnifera, extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :IJCREE International Journal of Crude Drug Research. (Swets & ZeitlingerB.V., POB 825, 2160 SZ Lisse, Netherlands) V.20- 1982-
| 56749-17-8 |
Withania somnifera Linn., aerial parts extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:26,163,1989
| 56749-17-8 |
Withania somnifera (L.) Dunal, root extractSUBSTANCE DEFINITION :Plant belonging to the family SolanaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 56749-17-8 |
Wollastonite
| 13983-17-0 |
Wood dust
| 13983-17-0 |
Woodfordia fruticosa Kurz, flower extractSUBSTANCE DEFINITION :Plant belonging to the family LythraceaeREFERENCE :IJMRAQ Indian Journal of Medical Research. (Indian Council of MedicalResearch, Ansari Nagar, New Delhi 110 029, India) V.1- 1913-
| 13983-17-0 |
Venom, spider, Acanthoscurria atrox
| 13983-17-0 |
Wood smoke condensate, hickory
| 13983-17-0 |
Wood tar, creosoteSUBSTANCE DEFINITION :Mixture comprising about 20 to 35% guaiacol, about 15 to 25% creosol andvarious phenol derivativesREFERENCE :EPXXDW European Patent Application. (U.S. Patent and Trademark Office,Foreign Patents, Washington, DC 20231)
| 13983-17-0 |
Wood vinegar
| 8030-97-5 |
Woodwardia radicans Sm., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family BlechnaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
| 8030-97-5 |
Woodwardia unigemmata (Makino)Nakai, extractSUBSTANCE DEFINITION :Indian plant belonging to the family BlechnaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 8030-97-5 |
Wool Fabric, pyrolyzate
| 8030-97-5 |
WR 2529 AK
| 8030-97-5 |
Wrightia cocciniea (Roxb.) Sims., extractSUBSTANCE DEFINITION :Plant belonging to the family ApocynaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977
| 8030-97-5 |
Wrightia tintoria R. Br., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family ApocynaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8030-97-5 |
Wrightia tomentosa R. & S., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family ApocynaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8030-97-5 |
Venom, spider, Acanthoscurria musculosa
| 8030-97-5 |
WR 2529 RCL
| 8030-97-5 |
WSR-301
| 25322-68-3 |
Xanthalicin B
| 102583-68-6 |
Xanthellin
| 1405-04-5 |
3H-Xanthen-6-amine, N-methyl-3-(methylimino)-,hydrochloride
| 2465-29-4 |
Xanthene
| 92-83-1 |
Xanthene-2-acetic acid, 7-chloro-9-oxo-
| 51925-02-1 |
Xanthene-9-acetic acid, alpha-cyano-,2-(diethylamino)ethyl ester, hydrochloride
| 51925-02-1 |
Xanthene-9-acetic acid, 2-(dicyclohexylamino)ethylester, hydrochloride
| 103161-33-7 |
Xanthene-9-acetic acid, 2-(diethylamino)ethyl ester,hydrochloride
| 13210-09-8 |
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