*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CU6125000
CHEMICAL NAME : Benzaldehyde, 3-ethoxy-4-hydroxy-
CAS REGISTRY NUMBER : 121-32-4
BEILSTEIN REFERENCE NO. : 1073761
REFERENCE : 4-08-00-01765 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C9-H10-O3
MOLECULAR WEIGHT : 166.19
WISWESSER LINE NOTATION : VHR DQ CO2
COMPOUND DESCRIPTOR : Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Bourbonal
* Ethavan
* Ethovan
* 3-Ethoxy-4-hydroxybenzaldehyde
* Ethylprotal
* Ethyl vanillin
* 4-Hydroxy-3-ethoxybenzaldehyde
* Protocatechuic aldehyde ethyl ether
* Quantrovanil
* Vanillal
* Vanillin, ethyl-
* Vanirom
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 10 mg/48H
REACTION SEVERITY : Mild
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 13,103,1975
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1590 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 44A,39,1967
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 29,425,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher
information, see JTCTDW. Volume(issue)/page/year: 10,61,1977
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
(Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV.
Volume(issue)/page/year: 238,2576,1954
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 29,425,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >7940 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0534355
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
(Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV.
Volume(issue)/page/year: 238,2576,1954
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4480 mg/kg/70D-I
TOXIC EFFECTS :
Cardiac - other changes
Blood - changes in spleen
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 29,425,1940
** MUTATION DATA **
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 1 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Fibroblast
DOSE/DURATION : 250 mg/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,623,1984
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M4743
No. of Facilities: 26 (estimated)
No. of Industries: 2
No. of Occupations: 17
No. of Employees: 2343 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M4743
No. of Facilities: 2917 (estimated)
No. of Industries: 20
No. of Occupations: 42
No. of Employees: 53949 (estimated)
No. of Female Employees: 31080 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Benzaldehyde, 3,4-dimethoxy-,(3-(2-(3,4-dimethoxyphenyl)ethyl)-4-oxo-2-thiazolidinylidene)hydrazone
| 53068-41-0 |
Benzaldehyde, 3,5-dimethoxy-4-hydroxy-
| 134-96-3 |
Benzaldehyde, 3,5-dimethoxy-4-hydroxy-, chlorinated
| 134-96-3 |
Barbituric acid, 5-(1-(ethylthio)ethyl)-5-isobutyl-,sodium salt
| 67051-05-2 |
Benzaldehyde, 3,5-dimethoxy-4-hydroxy-, oxime
| 5032-13-3 |
Benzaldehyde,(3-(2-(3,4-dimethoxyphenyl)ethyl)-4-oxo-2-thiazolidinylidene)hydrazone
| 53068-35-2 |
Benzaldehyde, 3,4-dimethoxy-,(p-tricyanovinylphenyl)hydrazone
| 73664-54-7 |
Benzaldehyde, dimethyl acetal
| 1125-88-8 |
Benzaldehyde, p-(dimethylamino)-
| 100-10-7 |
Benzaldehyde, 4-(dimethylamino)-,9-acridinylhydrazone
| 94388-26-8 |
Benzaldehyde, p-(dimethylamino)-,bis(2-chloroethyl)hydrazone
| 94379-84-7 |
Benzaldehyde, p-(dimethylamino)-,2,2-bis(2-chloroethyl)hydrazone, monohydrochloride
| 102585-94-4 |
Benzaldehyde, p-(dimethylamino)-,(p-bromophenyl)hydrazone
| 27246-80-6 |
Benzaldehyde, p-dimethylamino-,(2-(2-chloroethyl)-2-methyl)hydrazone
| 62258-26-8 |
Barbituric acid, 5-(ethylthiomethyl)-5-hexyl-, sodiumsalt
| 67051-06-3 |
Benzaldehyde, 4-(dimethylamino)-,(3-(2-(3,4-dimethoxyphenyl)ethyl)-4-oxo-2-thiazolidinylidene)hydrazone
| 53068-43-2 |
Benzaldehyde, p-(dimethylamino)-,(5-nitro-2-pyridyl)hydrazone
| 28129-69-3 |
Benzaldehyde, m-((p-(dimethylamino)phenyl)azo)-
| 69321-17-1 |
Benzaldehyde, 4-((4-(dimethylamino)phenyl)azo)-
| 39208-00-9 |
Benzaldehyde, p-dimethylamino-, 3-thiosemicarbazone
| 2929-81-9 |
Benzaldehyde, 2,6-dimethyl-,O-(2-(diethylamino)ethyl)oxime, monohydrochloride
| 13445-36-8 |
Benzaldehyde,3-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-,(E)-2- butenedioate (2:1) (salt)
| 56138-52-4 |
Benzaldehyde, (4,6-dimethyl-3-pyridazinyl)hydrazone
| 17258-28-5 |
Benzaldehyde, 2,4-dinitro-
| 528-75-6 |
Benzaldehyde, 2,6-dinitro-
| 606-31-5 |
Barbituric acid,5-(ethylthiomethyl)-5-isobutyl-1-methyl-, sodium salt
| 67051-08-5 |
Benzaldehyde, p-ethoxy-
| 10031-82-0 |
Benzaldehyde, o-ethoxy-, (p-bromophenyl)hydrazone
| 27343-19-7 |
Benzaldehyde, p-ethoxy-, (p-chlorophenyl)hydrazone
| 27241-94-7 |
Benzaldehyde, 3-ethoxy-2-hydroxy-
| 492-88-6 |
Benzaldehyde, 3-ethoxy-4-hydroxy-
| 121-32-4 |
Benzaldehyde, 4-ethoxy-3-hydroxy-
| 2539-53-9 |
Benzaldehyde, 3-ethoxy-4-hydroxy-,(5-nitro-2-pyridyl)hydrazone
| 28058-39-1 |
Benzaldehyde, p-ethoxy-, (P-iodophenyl)hydrazone
| 27246-92-0 |
Benzaldehyde, 4-ethoxy-3-methoxy-,(3-(2-(3,4-dimethoxyphenyl)ethyl)-4-oxo-thiazolidinylidene)hydrazone
| 53068-42-1 |
Benzaldehyde, 3-ethoxy-4-methoxy-, oxime
| 53068-42-1 |
Barbituric acid,5-ethyl-1-(2-oxo-4-piperidinobutyl)-5-phenyl-,hydrochloride
| 53068-42-1 |
Barbituric acid, 5-(ethylthiomethyl)-5-isobutyl-,sodium salt
| 73688-60-5 |
Benzaldehyde, 2-ethoxy-, (5-nitro-2-pyridyl)hydrazone
| 28058-28-8 |
Benzaldehyde, p-ethylsulfonyl-, benzoxazolylhydrazone
| 6291-30-1 |
Benzaldehyde, 2-fluoro-
| 446-52-6 |
Benzaldehyde, m-fluoro-, (p-bromophenyl)hydrazone
| 27246-90-8 |
Benzaldehyde, p-fluoro-, (p-bromophenyl)hydrazone
| 27246-88-4 |
Benzaldehyde, p-fluoro-, O-(diethylaminoethyl)oxime,hydrochloride, (E)-
| 61734-02-9 |
Benzaldehyde, p-fluoro-, O-(2-morpholinoethyl)oxime,hydrochloride, (E)-
| 61734-13-2 |
Benzaldehyde, 4-fluoro-2-nitro-
| 2923-96-8 |
Benzaldehyde, p-fluoro-, (5-nitro-2-pyridyl)hydrazone
| 28058-11-9 |
Benzaldehyde, p-fluoro-, oxime
| 459-23-4 |
Barbituric acid,5-(ethylthiomethyl)-5-isobutyl-2-thio-, sodium salt
| 67051-09-6 |
Benzaldehyde, 3-fluoro-,(2-oxo-2-(10H-phenothiazin-10-yl)ethyl)hydrazone
| 66786-23-0 |
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