*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DA4795700
CHEMICAL NAME : Benzenemethanol, 3-((4-(dimethylamino)phenyl)azo)-
CAS REGISTRY NUMBER : 35282-69-0
BEILSTEIN REFERENCE NO. : 1821443
LAST UPDATED : 199612
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C15-H17-N3-O
MOLECULAR WEIGHT : 255.35
WISWESSER LINE NOTATION : Q1R CNUNR DN1&1
COMPOUND DESCRIPTOR : Tumorigen
Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Benzyl alcohol, m-((p-dimethylaminophenyl)azo)-
* m-((p-Dimethylaminophenyl)azo)benzyl alcohol
* 3-((p-Dimethylamino)phenylazo)benzyl alcohol
* 3'-Hydroxymethyl-N,N-dimethyl-4-aminoazobenzene
* 3'-Hydroxymethyl-4-(dimethylamino)azobenzene
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6451 mg/kg/24W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Liver - tumors
REFERENCE :
NAIZAM Nara Igaku Zasshi. Journal of the Nara Medical Association. (Nara
Igakkai, c/o Narakenritsu Ika Daigaku, Shijo-cho, Kashihara, Nara-ken,
Japan) V.1- 1950- Volume(issue)/page/year: 37,653,1986
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2280 mg/kg/13W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
REFERENCE :
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75,
1907-84. For publisher information, see JJCREP. Volume(issue)/page/year:
72,160,1981
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4880 mg/kg/13W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
REFERENCE :
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75,
1907-84. For publisher information, see JJCREP. Volume(issue)/page/year:
72,160,1981
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2563 mg/kg/30D-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
Liver - tumors
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 1,533,1980
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5240 mg/kg/90D-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
Liver - tumors
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 1,533,1980
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3600 mg/kg/17W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Liver - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC)
V.61-79, 1978-87. For publisher information, see JNCIEQ.
Volume(issue)/page/year: 79,1159,1987
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 umol/plate
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 4,1487,1983
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 umol/L
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 32,3641,1984
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 1 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
46,1654,1986
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Benzenemethanol,2,4-dichloro-alpha-(4-(2-(4-morpholinyl)ethoxy)phenyl)-, hydrochloride
| 42740-31-8 |
Benzenemethanol,4-(2-(diethylamino)ethoxy)-alpha-ethyl-alpha-phenyl-
| 56431-20-0 |
Benzenemethanol,alpha-((((3,4-dihydro-6,7-dimethoxy-1H-2-benzopyran-1-yl)methyl)methylamin o) methyl)-
| 70070-21-2 |
Benzenemethanol,alpha-(1-((2,3-dihydro-2-methyl-1,4-benzodioxin-2-yl)methyl)amino)ethyl)-4- hydroxy-, hydrobromide
| 87081-19-4 |
Benzenemethanol,3,5-diiodo-4-hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-
| 22103-14-6 |
Benzenemethanol,2,5-dimethoxy-alpha-(1-((2-hydroxyethyl)amino)ethyl)-
| 22103-14-6 |
Benzenemethanol,alpha-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methyl)-4-hydroxy-, (R)-
| 71771-90-9 |
Benzenemethanol,alpha-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methyl)-3-methoxy-4-hydroxy-, hydrochloride, (R)-
| 71771-90-9 |
Benzeneethanamine, alpha-methyl-2-(phenylthio)-,(Z)-2-butenedioate (1:1)
| 127876-81-7 |
Benzeneethanethioamide, N-(2-(1H-indol-3-yl)ethyl)-
| 10022-76-1 |
Benzenemethanol, 2,4-dimethyl-, acetate
| 62346-96-7 |
Benzenemethanol,alpha-(2-(dimethylamino)ethyl)-4-ethoxy-,hydrochloride
| 24221-40-7 |
Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-,hydrochloride, (R-(R*,S*))-
| 38455-90-2 |
Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-,hydrochloride, (S-(R*,R*))-
| 65326-26-3 |
Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-,hydrochloride, (S-(R*,S*))-
| 54114-10-2 |
Benzenemethanol, alpha-((dimethylamino)methyl)-,hydrochloride, (+-)-
| 939-44-6 |
Benzenemethanol, alpha-((dimethylamino)methyl)-,hydrochloride, (R)-
| 939-43-5 |
Benzenemethanol, 3-((4-(dimethylamino)phenyl)azo)-
| 35282-69-0 |
Benzenemethanol, 2-((4-(dimethylamino)phenyl)azo)-,acetate (ester)
| 78914-74-6 |
Benzenemethanol, 3-((4-(dimethylamino)phenyl)azo)-,acetate (ester)
| 75125-64-3 |
Benzeneethanimidamide, N-phenyl-
| 7118-59-4 |
Benzenemethanol, 4-((4-(dimethylamino)phenyl)azo)-,acetate (ester)
| 78914-75-7 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-, acetate(salt)
| 72156-33-3 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-,butanedioate (salt) (2:1)
| 72156-36-6 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-,(E)-2-butenedioate (salt) (2:1)
| 72156-35-5 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-2-fluoro-,hydrochloride
| 82101-08-4 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-4-fluoro-,hydrochloride
| 85540-78-9 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-,hydrochloride
| 85540-78-9 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-3-(((4-methoxyphenyl) methyl)amino)-, hydrochloride
| 60853-38-5 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-,methanesulfonate (salt)
| 72156-37-7 |
Benzenemethanol,alpha-(((1,1-dimethylethyl)amino)methyl)-, propanoate(salt)
| 72156-34-4 |
Benzeneethanimidoyl chloride,N,4-dihydroxy-alpha-oxo-
| 34911-46-1 |
Benzenemethanol,2,5-dimethyl-alpha-ethyl-alpha-(4-((6-methyl-2-pyridinyl)methoxy)phenyl)-
| 92814-09-0 |
Benzenemethanol,2,5-dimethyl-alpha-ethyl-alpha-phenyl-
| 56431-19-7 |
Benzenemethanol,alpha-(((1,1-dimethyl-2-hydroxyethyl)amino)methyl)-
| 36981-91-6 |
Benzenemethanol,alpha-(((1,1-dimethyl-2-hydroxyethyl)amino)methyl)-,hydrochloride
| 67704-50-1 |
Benzenemethanol, 2,6-dinitro-
| 96839-34-8 |
Benzenemethanol,3,5-dinitro-4-((1-ethylpropyl)amino)-2-methyl-
| 56750-76-6 |
Benzenemethanol,alpha-((1,3,5,7,9-dodecapentadienyloxy)methyl)-,(all-E)-
| 139953-98-3 |
Benzenemethanol, alpha-ethenyl-, acetate
| 7217-71-2 |
Benzenemethanol, alpha-ethenyl-3,4-dimethoxy-
| 31706-95-3 |
Benzenemethanol,alpha-(((ethyl(1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)oxy) carbonyl)-, acetate (ester)
| 94593-40-5 |
Benzeneethanol, 4-(3-aminocyclohexyl)-
| 73823-81-1 |
Benzenemethanol,alpha-((ethyl(1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino) methyl)-, hydrochloride
| 116680-73-0 |
Benzenemethanol,alpha-((ethyl(1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino)methyl )- 4-methyl-, hydrochloride
| 116680-71-8 |
Benzenemethanol,alpha-((ethyl(1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino)methyl )- 4-(trifluoromethyl)-,hydrochloride
| 116680-77-4 |
Benzenemethanol,4-(ethylthio)-alpha-(1-(octylamino)ethyl)-,hydrochloride
| 54789-97-8 |
Benzenemethanol,4-(ethylthio)-alpha-(1-(octylamino)propyl)-,hydrochloride
| 54767-58-7 |
Benzenemethanol, alpha-ethynyl-alpha-phenyl-
| 3923-52-2 |
Benzenemethanol,4-fluoro-alpha-(((1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino) methyl)-, hydrochloride
| 116680-78-5 |
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