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MSDS  : Benzenemethanol, 4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)e thyl)-, hydrochloride, (R*,S*)-(+-)-
CAS  : 52447-11-7
SYNONYMS  : * (+-)-erythro-1-(p-Hydroxyphenyl)-2-(2-(p-hydroxyphenyl)ethylamino)-1-pro panol * (+-)-Ritodrine hydrochloride
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : DA4797100
CHEMICAL NAME : Benzenemethanol,
4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)e
thyl)-, hydrochloride, (R*,S*)-(+-)-
CAS REGISTRY NUMBER : 52447-11-7
LAST UPDATED : 198706
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C17-H21-N-O3.Cl-H
MOLECULAR WEIGHT : 323.85
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* (+-)-erythro-1-(p-Hydroxyphenyl)-2-(2-(p-hydroxyphenyl)ethylamino)-1-pro
panol
* (+-)-Ritodrine hydrochloride

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1840 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 352 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 980 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 83 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2175 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 298 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 815 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 71 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 17,1106,1986

*** END OF RECORD ***
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NAMECAS
Benzenemethanol,alpha-(1-(heptylamino)ethyl)-4-((1-methylethyl)thio)- 54767-66-7
Benzenemethanol,alpha-(1-(hexylamino)ethyl)-4-((1-methylethyl)thio)- 54767-65-6
Benzenemethanol, 4-hydrazino- 73454-78-1
Benzeneethanol, 4-(3-aminocyclohexyl)-beta-methyl- 73823-84-4
Benzenemethanol,alpha-(1-((2-hydroxyethyl)amino)-1-methylethyl)- 36981-89-2
Benzenemethanol,2-hydroxy-3-(1H-imidazol-4-ylmethyl)- 116795-97-2
Benzenemethanol,2-hydroxy-5-(1H-imidazol-4-ylmethyl)- 116796-03-3
Benzenemethanol,2-hydroxy-3-(1H-imidazol-4-ylmethyl)-5-methyl- 116796-00-0
Benzenemethanol,2-hydroxy-3-(1-(1H-imidazol-4-yl)pentyl)- 116796-02-2
Benzenemethanol,4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)-, (R*,S*)- 26652-09-5
Benzenemethanol,4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)-, hydrochloride, (R*,S*)-(+-)- 52447-11-7
Benzenemethanol,4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-,hydrochloride, (+-)- 881-95-8
Benzenemethanol,4-hydroxy-alpha-(((3-(2-methoxyphenyl)-1,1-dimethylpropyl)amino)methyl)- 72734-63-5
Benzenemethanol,3-hydroxy-alpha-((((4-methoxyphenyl)methylene)amino)methyl)- 72511-90-1
Benzeneethanol, 4-(bis(2-chloroethyl)amino)-, acetate(ester) 29427-51-8
Benzenemethanol,alpha-((((2-hydroxy-3-methoxy-5-(2-propenyl)phenyl)methyl)amino)methyl)- 54219-86-2
Benzenemethanol,3-hydroxy-alpha-((methylamino)methyl)-,alpha-acetate, hydrochloride 119610-76-3
Benzenemethanol,3-hydroxy-alpha-((methylamino)methyl)-, hydrochloride 20368-45-0
Benzenemethanol,4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-alpha-(methoxymethyl)- 56392-16-6
Benzenemethanol,4-hydroxy-alpha-(((1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino) methyl)-, hydrochloride 116680-79-6
Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)- 100199-60-8
Benzenemethanol,alpha-(((2-(3-methoxy-4-hydroxyphenyl)ethyl)amino)methyl)-4-hydroxy-, hydrochloride, (R)- 100199-60-8
Benzenemethanol,alpha-(((2-(3-methoxy-4-hydroxyphenyl)ethyl)amino)methyl)-3-methoxy-4- hydroxy-, hydrochloride, (R)- 100199-60-8
Benzenemethanol,3-(3-(4-(4-methoxyphenyl)-1-piperazinyl)propoxy)- 119335-96-5
Benzenemethanol,4-(3-(4-(4-methoxyphenyl)-1-piperazinyl)propoxy)- 119321-64-1
Benzeneethanol, 4-chloro-beta-(4-chlorophenyl)- 2642-82-2
Benzenemethanol,4-methoxy-alpha-(((1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino) methyl)-, hydrochloride 116680-74-1
Benzenemethanol, 4-methyl-, acetate 2216-45-7
Benzenemethanol, alpha-((methylamino)methyl)-, (+-)- 68579-60-2
Benzenemethanol, 4-(1-methylethyl)-, acetate 59230-57-8
Benzenemethanol,alpha-(1-((1-methylethyl)amino)ethyl)-4-((1-methylethyl)thio)-, hydrochloride 54821-85-1
Benzenemethanol,alpha-(1-((1-methylethyl)amino)ethyl)-4-((2-methylpropyl)thio)-, hydrochloride 54767-60-1
Benzenemethanol,alpha-(((1-methylethyl)amino)methyl)-, hydrochloride 10568-00-0
Benzenemethanol,4-((2-methylethylpropyl)thio)-alpha-(1-(octylamino)ethyl)- 54767-64-5
Benzenemethanol,4-((1-methylethyl)thio)-alpha-(1-((1-methylpropyl)amino)ethyl)-, hydrochloride 54767-45-2
Benzenemethanol,4-((1-methylethyl)thio)-alpha-(1-(octylamino)propyl)-, hydrochloride 54789-96-7
Benzeneethanol,4-chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-, hydrochloride 1215-83-4
Benzenemethanol,alpha-((methyl(1-methylethyl)amino)methyl)-,(E)-2-butenedioate (2:1) 80222-45-3
Benzenemethanol,alpha-((methyl(phenylmethyl)amino)methyl)-4-(methylsulfonyl)-, (Z)-2-butenedioate (1:1) 56621-62-6
Benzenemethanol,2-((2-((4-methyl-1-piperazinyl)methyl)phenyl)thio)-,dihydrochloride 93288-97-2
Benzenemethanol,alpha-((1-methyl-4-piperidinyl)ethynyl)-alpha-phenyl-, hydrochloride 91324-45-7
Benzenemethanol,4-methyl-alpha-((propyl(1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl) amino)methyl)-, hydrochloride 116680-68-3
Benzenemethanol,4-methyl-alpha-(((1,2,3,4-tetrahydro-6,7-dimethoxy-2-naphthalenyl)amino) methyl)-, hydrochloride 116680-72-9
Benzenemethanol,4-(methylthio)-alpha-(1-(octylamino)ethyl)-,hydrochloride 54767-50-9
Benzenemethanol,4-(methylthio)-alpha-(1-(octylamino)propyl)-,hydrochloride 54767-56-5
Benzenemethanol, 4-nitro-, propanoate 30039-44-2
Benzenemethanol,4-nitro-alpha-((1H-purin-6-ylthio)methyl)- 106609-67-0
Benzeneethanol,beta-(4-((4-chlorophenyl)methyl)phenoxy)-, (+-)- 71548-82-8
Benzenemethanol,alpha,alpha'-((phenylmethyl)phosphinylidene)bis- 36871-68-8
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