*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DB7329500
CHEMICAL NAME : Benzenesulfonic acid,
3-((4-(phenylamino)phenyl)azo)-, monosodium salt
CAS REGISTRY NUMBER : 587-98-4
LAST UPDATED : 199709
DATA ITEMS CITED : 15
MOLECULAR FORMULA : C18-H14-N3-O3-S.Na
MOLECULAR WEIGHT : 375.40
WISWESSER LINE NOTATION : WSO&R CNUNR DMR &-NA-
COMPOUND DESCRIPTOR : Drug
Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Acidic Metanil Yellow
* Acid Leather Yellow PRW
* Acid Leather Yellow R
* Acid Metanil Yellow
* Acid Yellow 36
* Aizen Metanil Yellow
* Amacid Yellow M
* Brasilan Metanil Yellow
* Bucacid Metanil Yellow
* Calcocid Yellow MXXX
* C.I. 13065
* C.I. Acid Yellow 36
* C.I. Acid Yellow 36 monosodium salt
* Diacid Metanil Yellow
* Eniacid Metanil Yellow GN
* Ext D and C Yellow No. 1
* Fenazo Yellow M
* Hidacid Metanil Yellow
* Hispacid Yellow MG
* Java Metanil Yellow G
* Kiton Orange MNO
* Kiton Yellow MS
* Metanile Yellow O
* Metanil Yellow
* Metanil Yellow 1955
* Metanil Yellow C
* Metanil Yellow E
* Metanil Yellow Extra
* Metanil Yellow F
* Metanil Yellow G
* Metanil Yellow Griesbach
* Metanil Yellow K
* Metanil Yellow KRSU
* Metanil Yellow M3X
* Metanil Yellow O
* Metanil Yellow PL
* Metanil Yellow S
* Metanil Yellow Supra P
* Metanil Yellow VS
* Metanil Yellow WS
* Metanil Yellow Y
* Metanil Yellow YK
* Mitsui Metanil Yellow
* Monoazo
* Remaderm Yellow HPR
* Shikiso Metanil Yellow
* Symulon Metanil Yellow
* Takaoka Metanil Yellow
* Tertracid Yellow M
* Tropaeolin G
* Vondacid Metanil Yellow G
* 11363 Yellow
* Yodochrome Metanil Yellow
* Zlut kysela 36
* Zlut metanilova
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1310,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SRTCDF Scientific Report. (Dr. C.R. Krishna Murti, Director, Industrial
Toxicology Research Centre, Luchnow-226001, India) History unknown.
Volume(issue)/page/year: -,11,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1310,1986
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1800 mg/kg/90D-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes
Autonomic Nervous System - sympathomimetic
Behavioral - alteration of operant conditioning
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
31,41,1993
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6450 mg/kg/15D-I
TOXIC EFFECTS :
Gastrointestinal - other changes
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other transferases
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins
Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
Volume(issue)/page/year: 17,85,1996
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 240 mg/kg/3D-I
TOXIC EFFECTS :
Liver - other changes
Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co.,
POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year:
8,63,1992
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 540 gm/kg/26W-C
TOXIC EFFECTS :
Blood - normocytic anemia
Blood - changes in other cell count (unspecified)
Blood - changes in erythrocyte (RBC) count
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 16,103,1983
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 162 gm/kg
SEX/DURATION : male 90 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
REFERENCE :
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 15,227,1978
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Human Leukocyte
DOSE/DURATION : 10 umol/L
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 16,820,1978
TYPE OF TEST : Mutation in mammalian somatic cells
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 22 nmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,265,1991
TYPE OF TEST : Cytogenetic analysis
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 60 mg/kg/30D (Continuous)
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year:
30,315,1986
TYPE OF TEST : Sister chromatid exchange
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 5 mg/kg
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year:
31,299,1986
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M1438
No. of Facilities: 455 (estimated)
No. of Industries: 10
No. of Occupations: 22
No. of Employees: 5070 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M1438
No. of Facilities: 2370 (estimated)
No. of Industries: 32
No. of Occupations: 33
No. of Employees: 52679 (estimated)
No. of Female Employees: 18156 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Benzenesulfonic acid, 4-methyl-2-(phenylsulfonyl)-,hydrazide
| 37049-79-9 |
Benzenesulfonic acid, compd. with10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfinyl)ethyl)-10H-phenothiazine (1:1)
| 32672-69-8 |
Benzenesulfonic acid, 4-methyl-,(2-pyridinylmethylene)hydrazide, N-oxide
| 50908-22-0 |
Benzenesulfonic acid, methyl-, sodium salt
| 12068-03-0 |
Benzenesulfonic acid, (1-methylundecyl)-, sodium salt
| 27987-00-4 |
Benzenesulfonic acid,5-(2H-naphtho(1,2-d)triazol-2-yl)-2-(2-phenylethenyl)-, sodium salt
| 6416-68-8 |
Benzenesulfonic acid, m-nitro-
| 98-47-5 |
Benzenesulfonamide,N-(2,3-dihydro-5-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-1H- inden-2-yl)-
| 114149-44-9 |
Benzenesulfonamide,4-(2,5-dioxo-3-methyl-3-phenyl-1-pyrrolidinyl)-2-fluoro-
| 31150-98-8 |
Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester,(R)-
| 115314-17-5 |
Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester,(S)-
| 115314-14-2 |
Benzenesulfonic acid, nitro-, sodium salt
| 27215-71-0 |
Benzenesulfonic acid, m-nitro-, sodium salt
| 127-68-4 |
Benzenesulfonic acid, p-nitro-, 2,2,2-tribromoethylester
| 73688-64-9 |
Benzenesulfonic acid, p-nitro-, 2,2,2-trichloroethylester
| 73688-65-0 |
Benzenesulfonic acid, nonyl-, sodium salt
| 26856-61-1 |
Benzenesulfonic acid, p-(3-(octylthio)propyl)-,sodium salt
| 7545-13-3 |
Benzenesulfonic acid, p-(3-oxo-3-phenyl-1-propenyl)-,sodium salt
| 30056-77-0 |
Benzenesulfonic acid, 4,4'-oxybis-, dihydrazide
| 80-51-3 |
Benzenesulfonamide,4-(2,5-dioxo-3-methyl-4-propyl-1-pyrrolidinyl)-
| 65116-24-7 |
Benzenesulfonic acid, 2,2'-oxybis(4-dodecyl-,disodium salt
| 5136-51-6 |
Benzenesulfonic acid,p-((5-(3-(p-(pentyloxy)phenyl)-2-thioureido)-2-ethoxy-1-phenyl) methoxy)-, sodium salt
| 33312-74-2 |
Benzenesulfonic acid,m-(3-(p-(pentyloxy)phenyl)-2-thioureido)-, sodiumsalt
| 22938-53-0 |
Benzenesulfonic acid,p-(3-(p-(pentyloxy)phenyl)-2-thioureido)-, sodiumsalt
| 22938-51-8 |
Benzenesulfonic acid, phenoxy-, monododecyl deriv.,sodium salt
| 53467-00-8 |
Benzenesulfonic acid,3-((4-(phenylamino)phenyl)azo)-, monosodium salt
| 587-98-4 |
Benzenesulfonic acid,4-(((phenylamino)thioxomethyl)amino)-,2-(2-benzothiazolyl)hydrazide
| 116854-85-4 |
Benzenesulfonic acid,4-(4-phenyl-1,4-dihydropyrimido(1,2-a)benzimidazol-2-yl)-, 2,2,3,3- tetrafluoropropyl ester
| 169132-76-7 |
Benzenesulfonic acid,4-((6-phenylimidazo(2,1-b)thiazol-3(2H)-ylidene)amino)-
| 106444-31-9 |
Benzenesulfonic acid,4-((((phenylmethyl)amino)thioxomethyl)amino)-,2-(2-benzothiazolyl) hydrazide
| 116854-86-5 |
Benzenesulfonamide,4-(2,5-dioxo-3-methyl-1-pyrrolidinyl)-
| 65116-12-3 |
Benzenesulfonic acid, p-(3-phenyl-1-pyrazolyl)-
| 78109-90-7 |
Benzenesulfonic acid, 2-(1-piperazinyl)-5-propyl-,hydrochloride
| 78109-90-7 |
Benzenesulfonic acid,4,4'-(3-(2-pyridyl)-triazine-5,6-diyl)di-, disodiumsalt
| 28048-33-1 |
Benzenesulfonic acid, sodium salt
| 515-42-4 |
Benzenesulfonic acid,3,3'-(4,5,6,7-tetrachloro-3-oxo-1(3H)-isobenzofuranylidene)bis (6-hydroxy-, disodium salt
| 5182-09-2 |
Benzenesulfonic acid, tetradecyl-
| 30776-59-1 |
Benzenesulfonic acid, p-(1,1,4,4-tetramethyloctyl)-,sodium salt
| 30776-59-1 |
Benzenesulfonic acid, tetrapropylene-
| 11067-81-5 |
Benzenesulfonic acid, tetrapropylene-, sodium salt
| 11067-82-6 |
Benzenesulfonic acid, thio-,S,S'-(2-(dimethylamino)trimethylene) ester
| 17606-31-4 |
Benzenesulfonamide,4-(2,5-dioxo-3-methyl-1-pyrrolidinyl)-3-fluoro-
| 30279-50-6 |
Benzenesulfonic acid, thio-, S-trichlorovinyl ester
| 16627-02-4 |
Benzenesulfonic acid,2-((2,4,6-triamino-5-pyrimidinyl)azo)-
| 16627-02-4 |
Benzenesulfonic acid,4-((2,4,6-triamino-5-pyrimidinyl)azo)-
| 2877-65-8 |
Benzenesulfonic acid, 2,4,5-trichloro-, hydrazide
| 6655-72-7 |
Benzenesulfonic acid,3-(3,4,5-triiodobenzenesulfonamido)-
| 6655-72-7 |
Benzenesulfonic acid,4-(3,4,5-triiodobenzenesulfonamido)-, sodium salt
| 6655-72-7 |
Benzenesulfonic acid,5,5'-(4,5,6,7-tetraiodo-3-oxo-1(3H)-isobenzofuranylidene)bis(2-hydroxy-,di sodium salt
| 5549-75-7 |
Benzenesulfonic acid, 2,4,6-trinitro-, compd. withN-(4-chlorobutyl)-N-(2-chloroethyl)- benzylamine
| 94379-83-6 |
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