RTECS NUMBER : DV8203000
CHEMICAL NAME : 1,1'-Biphenyl, 2,3',4,4',5-pentachloro-
CAS REGISTRY NUMBER : 31508-00-6
BEILSTEIN REFERENCE NO. : 2379471
LAST UPDATED : 199712
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C12-H5-Cl5
MOLECULAR WEIGHT : 326.42
COMPOUND DESCRIPTOR : Tumorigen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Biphenyl, 2,3',4,4',5-pentachloro-
* PCB 118
* 2,3',4,4',5-Pentachlorobiphenyl
* 3,4,2',4',5'-Pentachlorobiphenyl
*** HEALTH HAZARD DATA ***
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 15470 ug/kg/13W-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes
Liver - other changes
Biochemical - Neurotransmitters or modulators (putative) - dopamine at other
sites
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
26,282,1995
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 28 mg/kg
SEX/DURATION : female 10-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 68,311,1993
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 112 mg/kg
SEX/DURATION : female 10-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
Reproductive - Effects on Newborn - behavioral
Reproductive - Effects on Newborn - physical
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
26,117,1995
*** STATUS IN U.S. ***
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NTP Carcinogenesis studies; selected, October 1997
*** END OF RECORD ***
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP