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MSDS  : Carbamic acid, ((2-((methoxyacetyl)amino)-4-(phenylthio)phenyl)carbo nimidoyl)bis-, dimethyl ester
CAS  : 58306-30-2
SYNONYMS  : * BAY Vh5757 * N-(2-(2,3-Bis-(methoxycarbonyl)-guanidino)-5-(phenylthio)-phenyl)-2-meth oxyacetamide * Febantel * Rintal
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : FB3955000
CHEMICAL NAME : Carbamic acid,
((2-((methoxyacetyl)amino)-4-(phenylthio)phenyl)carbo
nimidoyl)bis-, dimethyl ester
CAS REGISTRY NUMBER : 58306-30-2
BEILSTEIN REFERENCE NO. : 2195764
LAST UPDATED : 199612
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C20-H22-N4-O6-S
MOLECULAR WEIGHT : 446.52
WISWESSER LINE NOTATION : 1OVNUYMVO1&MR DSR& BMV1O1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* BAY Vh5757
* N-(2-(2,3-Bis-(methoxycarbonyl)-guanidino)-5-(phenylthio)-phenyl)-2-meth
oxyacetamide
* Febantel
* Rintal

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10605 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - domestic
DOSE/DURATION : >200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 28,2193,1978

*** END OF RECORD ***
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Carbamic acid, 2-hydroxy-3-(o-tolyloxy)propyl ester 533-06-2
Carbamic acid, N-hydroxy-, 2,3,5-trimethylphenylester 533-06-2
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Carbamic acid, (p-iodobenzyl)-, hexyl ester 67987-35-3
Carbamic acid, (2-isobutoxyethyl) ester 16006-09-0
Carbamic acid, isobutyl-,2-(hydroxymethyl)-2-methylpentyl ester, carbamate(ester) 25384-83-2
Carbamic acid, N-isobutyl-N-nitroso-, ethyl ester 24423-85-6
Carbamic acid, isobutyrylmethyl-, m-cumenyl ester 5748-26-5
Carbamic acid, isopentyl-, 2-chloroethyl ester 60452-10-0
Carbamic acid, isopentyl ester 543-86-2
Carbamic acid, (3-(decyloxy)phenyl)-,2-(1-piperidinyl)ethyl ester, monohydrochloride 55792-30-8
Carbamic acid, isopentyl-,2-(hydroxymethyl)-2-methylpentyl ester,butylcarbamate (ester) 25648-93-5
Carbamic acid, isopentyl-,2-(hydroxymethyl)-2-methylpentyl ester, carbamate(ester) 25384-88-7
Carbamic acid, (2-isopropoxyethyl) ester 67952-46-9
Carbamic acid, (3-isopropoxypropyl)-, 2-chloroethylester 60480-09-3
Carbamic acid,(2-isopropoxy-1-(o-tolyloxy)methylethyl) ester 64059-09-2
Carbamic acid, isopropyldithio-, phenyl ester 51098-13-6
Carbamic acid, isopropyl ester 1746-77-6
Carbamic acid, isopropyl-, ethyl ester 2594-20-9
Carbamic acid, isopropyl-,1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester 20977-50-8
Carbamic acid, isopropyl-,3-hydroxy-2,2-diphenylpropyl ester 25384-59-2
Carbamic acid, ((decyloxy)thio)methyl-,2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester 86627-78-3
Carbamic acid, isopropyl-,2-(hydroxymethyl)-2,3-dimethylpentyl ester 25384-47-8
Carbamic acid, isopropyl-,2-(hydroxymethyl)-2-methylpentyl ester 25462-17-3
Carbamic acid, isopropyl-,2-(hydroxymethyl)-2-methylpentyl ester carbamate(ester) 78-44-4
Carbamic acid, isopropyl-,2-(hydroxymethyl)-2-methylpentyl ester,propionylcarbamate (ester) 25648-91-3
Carbamic acid, isopropyl-,2-methyl-2-propyltrimethylene ester 1729-14-2
Carbamic acid, isopropyl-, 3-phenylpropyl ester 92196-89-9
Carbamic acid, isopropyl-, 4-pyridylmethyl ester 4867-59-8
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Carbamic acid, 2-mercaptoethyldithio- 69353-03-3
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Carbamic acid, N-mercapto-N-methyl-,m-isopropylphenyl ester 101491-88-7
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Carbamic acid, (mercaptophenylacetyl)-, ethyl ester,S-ester with O,O- diethyl phosphorothioate 3853-61-0
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Carbamic acid, (methoxyacetyl)methyl-,o-isopropoxyphenyl ester 17959-11-4
Carbamic acid, (methoxydithio)methyl-,2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester 86627-74-9
Carbamic acid, N-(3-(dibutylamino)propyl)dithio- 18997-73-4
Carbamic acid, (methoxymethyl)-,2-methyl-2-propyltrimethylene ester 25652-09-9
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Carbamic acid, (2-methoxyphenyl)-,3-((diethylamino)methyl)-1,7,7-trimethylbicyclo(2.2.1)hept-2-yl ester, monohydrochloride,(endo,endo)-(+-)- 149749-92-8

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