RTECS NUMBER : FL6900000
CHEMICAL NAME : Chalcone
CAS REGISTRY NUMBER : 94-41-7
LAST UPDATED : 199706
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C15-H12-O
MOLECULAR WEIGHT : 208.27
WISWESSER LINE NOTATION : RV1U1R
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Acrylophenone, 3-phenyl-
* Benzalacetophenone
* 2-Benzalacetophenone
* 1-Benzoyl-1-phenylethene
* beta-Benzoylstyrene
* alpha-Benzylideneacetophenone
* 2-Benzylideneacetophenone
* Chalkone
* Cinnamophenone
* 1,3-Diphenylpropenone
* 1,3-Diphenyl-1-propen-3-one
* beta-Phenylacrylophenone
* 3-Phenylacrylophenone
* 1-Phenyl-2-benzoylethylene
* Phenyl 2-phenylvinyl ketone
* Phenyl styryl ketone
* 2-Propen-1-one, 1,3-diphenyl-
* Styryl phenyl ketone
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council,
Chemical-Biological Coordination Center, Review. (Washington, DC)
Volume(issue)/page/year: 5,28,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 681 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
Medicinal Chemistry. (Publications & Information Directorate, Council of
Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
India) V.14B- 1976- Volume(issue)/page/year: 18,65,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#04476
** MUTATION DATA **
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION : 250 units/L
REFERENCE :
ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 35,629,1964
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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