RTECS NUMBER : GZ1960000
CHEMICAL NAME : Cyclopropanecarboxylic acid,
2,2-dimethyl-3-(2-methylpropenyl)-,
(2-methyl-5-(2-propynyl)- 3-furyl)methyl ester
CAS REGISTRY NUMBER : 27223-49-0
LAST UPDATED : 199512
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C19-H24-O3
MOLECULAR WEIGHT : 300.43
COMPOUND DESCRIPTOR : Agricultural Chemical
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Kikuthrin
* 2-Methyl-5-(2-propynyl)-3-furylmethyl-cis-trans-chrysanthemate
* Proparthrin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 14 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
Japan) V.1- 1950- Volume(issue)/page/year: 36,533,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 44,325,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 44,325,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 8200 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42,
1937-77. Discontinued. Volume(issue)/page/year: 35,103,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 44,325,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >20 gm/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42,
1937-77. Discontinued. Volume(issue)/page/year: 35,103,1970
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 1500 mg/kg
SEX/DURATION : female 9-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42,
1937-77. Discontinued. Volume(issue)/page/year: 35,113,1970
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 6 gm/kg
SEX/DURATION : female 7-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42,
1937-77. Discontinued. Volume(issue)/page/year: 35,113,1970
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 30 gm/kg
SEX/DURATION : female 7-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
alive at weaning per # alive at day 4)
REFERENCE :
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42,
1937-77. Discontinued. Volume(issue)/page/year: 35,113,1970
*** END OF RECORD ***
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