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MSDS  : Dibenzo(b,def)chrysene-7,14-dione
CAS  : 128-66-5
SYNONYMS  : * Ahcovat Printing Golden Yellow * Amanthrene Golden Yellow * Anthravat Golden Yellow * Arlanthrene Golden Yellow * Benzadone Golden Yellow * Calcoloid Golden Yellow * Caledon Golden Yellow * Caledon Printing Yellow * Carbanthrene Golden Yellow * C.I. 59100 * Cibanone Golden Yellow * C.I. Vat Yellow * C.I. Vat Yellow 4 * Dibenzo(a,b)pyrene-7,14-dione * 2,3,7,8-Dibenzopyrene-1,6-quinone * 1',2',6',7'-Dibenzpyrene-7,14-quinone * Femanthren Golden Yellow * Golden Yellow * Helanthrene Yellow * Hostavat Golden Yellow * Indanthrene Golden Yellow * Indanthren Golden Yellow * Indanthren Printing Yellow * Leucosol Golden Yellow * Mayvat Golden Yellow * Mikethrene Gold Yellow * NCI-C03565 * Nihonthrene Golden Yellow * Nyanthrene Golden Yellow * Palanthrene Golden Yellow * Paradone Golden Yellow GK * Pharmanthrene Golden Yellow * Romantrene Golden Yellow * Sandothrene Golden Yellow * Sandothrene Printing Yellow * Solanthrene Brilliant Yellow * Tinon Golden Yellow GK * Tyrian Yellow I-GOK * Vat Golden Yellow * Vat Golden Yellow ZhKh * Vat Golden Yellow ZhKhD * Vat Yellow 4 * Yellow
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : HO7030000
CHEMICAL NAME : Dibenzo(b,def)chrysene-7,14-dione
CAS REGISTRY NUMBER : 128-66-5
BEILSTEIN REFERENCE NO. : 2000679
REFERENCE : 4-07-00-02709 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C24-H12-O2
MOLECULAR WEIGHT : 332.36
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* Ahcovat Printing Golden Yellow
* Amanthrene Golden Yellow
* Anthravat Golden Yellow
* Arlanthrene Golden Yellow
* Benzadone Golden Yellow
* Calcoloid Golden Yellow
* Caledon Golden Yellow
* Caledon Printing Yellow
* Carbanthrene Golden Yellow
* C.I. 59100
* Cibanone Golden Yellow
* C.I. Vat Yellow
* C.I. Vat Yellow 4
* Dibenzo(a,b)pyrene-7,14-dione
* 2,3,7,8-Dibenzopyrene-1,6-quinone
* 1',2',6',7'-Dibenzpyrene-7,14-quinone
* Femanthren Golden Yellow
* Golden Yellow
* Helanthrene Yellow
* Hostavat Golden Yellow
* Indanthrene Golden Yellow
* Indanthren Golden Yellow
* Indanthren Printing Yellow
* Leucosol Golden Yellow
* Mayvat Golden Yellow
* Mikethrene Gold Yellow
* NCI-C03565
* Nihonthrene Golden Yellow
* Nyanthrene Golden Yellow
* Palanthrene Golden Yellow
* Paradone Golden Yellow GK
* Pharmanthrene Golden Yellow
* Romantrene Golden Yellow
* Sandothrene Golden Yellow
* Sandothrene Printing Yellow
* Solanthrene Brilliant Yellow
* Tinon Golden Yellow GK
* Tyrian Yellow I-GOK
* Vat Golden Yellow
* Vat Golden Yellow ZhKh
* Vat Golden Yellow ZhKhD
* Vat Yellow 4
* Yellow

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 27(4),54,1983

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2270 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 27(4),54,1983

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 79500 mg/kg/6W-I
TOXIC EFFECTS :
Liver - liver function tests impaired
Blood - pigmented or nucleated red blood cells
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 27(4),54,1983

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 7420 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
REFERENCE :
NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
(Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
Volume(issue)/page/year: NCI-TR-134,1979

TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2225 gm/kg/106W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
REFERENCE :
NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
(Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
Volume(issue)/page/year: NCI-TR-134,1979

*** REVIEWS ***

IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 48,161,1990

IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 48,161,1990

IARC Cancer Review:Group 3
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 48,161,1990

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

NCI Carcinogenesis Bioassay (feed);clear evidence:mouse
NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
(Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
Volume(issue)/page/year: NCI-TR-134,79

NCI Carcinogenesis Bioassay (feed);no evidence:rat
NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
(Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
Volume(issue)/page/year: NCI-TR-134,79


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Dibenzo(b,def)chrysene-7-carboxaldehyde 14-methyl- 63040-57-3
Dibenzo(def,mno)chrysene-12-carboxaldehyde, 6-methyl- 63040-58-4
3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane,3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride 23476-83-7
Dibenzo(a,def)chrysene, 5,8-dihydro- 23476-83-7
Dibenzo(b,def)chrysene, 3,4-dihydro- 73691-48-2
Dibenzo(b,def)chrysene, 7,14-dihydro- 7350-86-9
Dibenzo(def,mno)chrysene, 4,5-dihydro- 35281-32-4
Bibenzo(def,mno)chrysene, 6,12-dimethyl- 41217-05-4
Dibenzo(b,def)chrysene-1,2-diol, 1,2-dihydro-, E- 73691-54-0
Dibenzo(def,mno)chrysene-6,12-dione 641-13-4
Dibenzo(b,def)chrysene-7,14-dione 128-66-5
Dibenzo(def,mno)chrysene-6,12-dione, 4,10-dibromo- 4378-61-4
Dibenzo(b,def)chrysene, 1,2-epoxy-1,2,3,4-tetrahydro- 78859-23-1
3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane,3,12-bis(2,3-dibromo-1-oxopropyl)-, dichloride,hemihydrate 95461-32-8
Dibenzo(def,mno)chrysene, 1,2,3,7,8,9-hexahydro- 35281-34-6
Dibenzo(def,mno)chrysene-6-methanol 105708-72-3
Dibenzo(def,mno)chrysene-6-methanol, acetate 105708-72-3
Dibenzo(b,def)chrysene, 5-methyl- 33942-87-9
Dibenzo(def,mno)chrysene, 12-methyl- 31927-64-7
Dibenzo(def,p)chrysene, 8-methyl- 63041-95-2
Dibenzo(def,p)chrysene, 10-methyl- 2869-60-5
Dibenzo(g,p)chrysene, 3,6,11,14-tetramethoxy- 60223-52-1
Dibenz(b,n)(1,4,7,10,13,16,19,22)octaoxacyclotetracosin, tetracosahydro- 17455-23-1
Dibenz(b,n)(1,4,7,10,13,16,19,22)octaoxacyclotetracosin, tetracosahydro-2,16(or2,17)-bis(1,1-dimethylethyl)- 70936-93-5
3,8-Diazabicyclo(3.2.1)octane,3-methyl-8-(3-phenylacryloyl)- 63977-92-4
3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane,3,12-bis(3-(diethylamino)-2- hydroxypropyl)-,dichloride 60013-04-9
5H-Dibenzo(a,d)cyclohepta-1,4-diene,5-(2-methylaminoethyloxyimino)-, hydrochloride 13055-76-0
1H-Dibenzo(3,46,7)cyclohepta(1,2-c)pyridine,2,3,4,9-tetrahydro-2-methyl- 57262-94-9
1H-Dibenzo(3,46,7)cyclohepta(1,2-c)pyridine,2,3,4,9-tetrahydro-2-methyl-, (Z)- 2-butenedioate 57262-94-9
Dibenzo(a,e)cycloheptatrien-5-ol,1-(diethylamino)methyl-2-methoxy- 42981-88-4
Dibenzo(a,e)cycloheptatrien-5-ol,1-(dimethylamino)methyl-2-methoxy-, hydrochloride 42981-87-3
Dibenzo(a,e)cycloheptatrien-5-ol,2-methoxy-1-morpholinomethyl- 42981-90-8
Dibenzo(a,e)cycloheptatrien-5-ol,2-methoxy-1-piperidinomethyl- 42981-89-5
Dibenzo(a,e)cycloheptatrien-5-ol,2-methoxy-1-pyrrolidinylmethyl- 42981-91-9
Dibenzo(a,e)cycloheptatrien-5-one,1-(diethylamino)methyl-2-methoxy- 42981-83-9
Dibenzo(a,e)cycloheptatrien-5-one,1-(dimethylamino)methyl-2-methoxy-, hydrochloride 42981-82-8
3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane,3,12-bis(2,3-dihydroxypropyl)-, dichloride 60013-05-0
Dibenzo(a,e)cycloheptatrien-5-one,2-methoxy-11-morpholinomethyl- 69352-74-5
Dibenzo(a,e)cycloheptatrien-5-one,2-methoxy-1-piperidinomethyl- 42981-84-0
Dibenzo(a,e)cycloheptatrien-5-one,2-methoxy-1-pyrrolidinomethyl- 42981-86-2
5H-Dibenzo(a,d)cyclohepten-5-amine,N,N-diethyl-10-(4-methyl-1-piperazinyl)- 56972-83-9
5H-Dibenzo(a,d)cyclohepten-5-amine,N,N-diethyl-10-(4-phenyl-1-piperazinyl)- 56972-82-8
5H-Dibenzo(a,d)cyclohepten-10-amine,10,11-dihydro-N-isopropyl- 31802-16-1
5H-Dibenzo(a,d)cyclohepten-10-amine,10,11-dihydro-N-(alpha-methylphenethyl)-,hydrochloride 31802-17-2
5H-Dibenzo(a,d)cyclohepten-5-amine,N,N-dimethyl-10-(4-methyl-1-piperazinyl)- 56972-84-0
5H-Dibenzo(a,d)cyclohepten-5-amine,N-ethyl-10-(4-methyl-1-piperazinyl)- 56972-85-1
5H-Dibenzo(a,d)cyclohepten-10-carbonitrile,5-(2-dimethylaminoethoxy)-, hydrogen maleate 24759-02-2
3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane,3,12-bis(dimethoxyphosphinothioyl)-, dichloride 111854-46-7
5H-Dibenzo(a,d)cyclohepten-10-carbonitrile,5-(3-alpha-tropanyloxy)-, hydrogen fumarate 27719-95-5
5H-Dibenzo(a,d)cyclohepten-10-carboxylic acid,2-(dimethylamino)ethyl ester, hydrogen fumarate 27720-08-7

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