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MSDS  : Acetone, thiosemicarbazone
CAS  : 1752-30-3
SYNONYMS  : * Acetonthiosemikarbazon * Hydrazinecarbothioamide, 2-(1-methylethylidene)- * 2-(1-Methylethylidene)hydrazinecarbothioamide * Thiosemicarbazone acetone
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AL7350000
CHEMICAL NAME : Acetone, thiosemicarbazone
CAS REGISTRY NUMBER : 1752-30-3
LAST UPDATED : 199712
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C4-H9-N3-S
MOLECULAR WEIGHT : 131.22
WISWESSER LINE NOTATION : SUYZMNUY1&1
COMPOUND DESCRIPTOR : Agricultural Chemical
SYNONYMS/TRADE NAMES :
* Acetonthiosemikarbazon
* Hydrazinecarbothioamide, 2-(1-methylethylidene)-
* 2-(1-Methylethylidene)hydrazinecarbothioamide
* Thiosemicarbazone acetone

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 48500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539438

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 72 mg/kg/4H
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539426

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 23 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 122,110,1958

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 19700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539438

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539438

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Ocular
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - acute pulmonary edema
Blood - hemorrhage
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539438

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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Acetyl chloride, diphenyl- 1871-76-7
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Acetyl chloride, o-nitrophenylhydrazone 39209-26-2
Acetyl chloride, p-nitrophenylhydrazone 39209-25-1
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Acetylene 74-86-2
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Acetylenedicarbonitrile 1071-98-3
Acetylenedicarboxamide 543-21-5
Acetylenedicarboxamide, hemihydrate 73663-83-9
Acetylenedicarboxylic acid, monopotassium salt 928-04-1
Acetonitrile 75-05-8
Acetylene, dichloro- 7572-29-4
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