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MSDS  : Aconitine, hydrobromide
CAS  : 6034-57-7
SYNONYMS  :
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AR5970000
CHEMICAL NAME : Aconitine, hydrobromide
CAS REGISTRY NUMBER : 6034-57-7
LAST UPDATED : 198712
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C34-H47-N-O11.Br-H
MOLECULAR WEIGHT : 726.74
WISWESSER LINE NOTATION : T65 B7 I5 I6 I6/CL/JP A K 5BIIJJ S IX NNTJ AOVR& COV1
DQ EO1 FQ KO1 N2 P1O1 QQ SO1
COMPOUND DESCRIPTOR : Drug

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2025 ug/kg
TOXIC EFFECTS :
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TJEMAO Tohoku Journal of Experimental Medicine. (Maruzen Co. Ltd., Export
Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan) V.1- 1920-
Volume(issue)/page/year: 128,175,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 428 ug/kg
TOXIC EFFECTS :
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TJEMAO Tohoku Journal of Experimental Medicine. (Maruzen Co. Ltd., Export
Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan) V.1- 1920-
Volume(issue)/page/year: 128,175,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 304 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TJEMAO Tohoku Journal of Experimental Medicine. (Maruzen Co. Ltd., Export
Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan) V.1- 1920-
Volume(issue)/page/year: 128,175,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 135 ug/kg
TOXIC EFFECTS :
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TJEMAO Tohoku Journal of Experimental Medicine. (Maruzen Co. Ltd., Export
Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan) V.1- 1920-
Volume(issue)/page/year: 128,175,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 60 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 33,80,1944

*** END OF RECORD ***
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