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MSDS  : Estra-1,3,5(10)-triene-16-alpha,17-beta-diol, 3-methoxy-
CAS  : 1474-53-9
SYNONYMS  : * Estra-1,3,5(10)-triene-16,17-diol, 3-methoxy-, (16-alpha,17-beta)- * Estriol methyl ether * Estriol 3-methyl ether * 3-Methoxyestriol
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : KG7540000
CHEMICAL NAME : Estra-1,3,5(10)-triene-16-alpha,17-beta-diol,
3-methoxy-
CAS REGISTRY NUMBER : 1474-53-9
LAST UPDATED : 199304
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C19-H26-O3
MOLECULAR WEIGHT : 302.45
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
Hormone
SYNONYMS/TRADE NAMES :
* Estra-1,3,5(10)-triene-16,17-diol, 3-methoxy-, (16-alpha,17-beta)-
* Estriol methyl ether
* Estriol 3-methyl ether
* 3-Methoxyestriol

*** HEALTH HAZARD DATA ***

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE : 5600 ug/kg
SEX/DURATION : male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Reproductive - Paternal Effects - testes, epididymis, sperm duct
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 15,16,1977

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Positive: Sperm morphology-rat


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Estra-1,3,5(10)-triene-3,17-diol, dibenzoate 52370-30-6
17-beta-Estra 1,3,5(10)-triene-3,17-diol,17-dihydrogen phosphate, homopolymer 34828-67-6
Estra-1,3,5(10)-triene-3,17-diol (17-beta)-,17-(2,2-dimethylhydrazinecarboxylate) 55081-70-4
Estra-1,3,5(10)-triene-3,17-beta-diol, 11-beta-ethyl- 64109-72-4
8-alpha-Estra-1,3,5(10)-triene-3,17-beta-diol,2-ethyl- 64109-72-4
8-alpha-Estra-1,3,5(10)-triene-3,17-beta-diol,16-beta-ethyl- 64109-72-4
Estra-1,3,5(10)-triene-3,17-beta-diol, 4-fluoro- 1881-37-4
Estra-1,3,5(10)-triene-16-alpha,17-beta-diol,3-methoxy- 1474-53-9
Estra-1,3,5(10)-triene-16-beta,17-beta-diol,3-methoxy-16-methyl- 5108-94-1
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 3-formyl-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate, O-(2-methoxy ethyl)oxime 41776-68-5
Estra-1,3,5(10)-triene-3,17-beta-diol,11-beta-methyl- 23637-93-6
8-alpha-Estra-1,3,5(10)-triene-3,17-beta-diol,2-methyl- 23637-93-6
8-alpha-Estra-1,3,5(10)-triene-3,17-beta-diol,16-methyl- 23637-93-6
8-alpha-Estra-1,3,5(10)-triene-3,17-beta-diol,16-beta-propyl- 23637-93-6
Estra-1,3,5(10)-triene-3,17-beta-diol,17-(3,3,3-trifluoro-1-propynyl)- 2061-56-5
Estra-1,3,5(10)-triene-2,3,17-beta-triol 362-05-0
Estra-1,3,5(10)-triene-3,4,17-beta-triol 5976-61-4
Estra-1,3,5(10)-triene-17-thiol, 3-methoxy- 5976-61-4
Estra-1,3,5(10)-triene-17-alpha-thiol, 3-methoxy- 102020-76-8
Estra-1,3,5(10)-triene-1,3,17-beta-triol 4147-05-1
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 3-formyl-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate, O-methyloxime 13292-54-1
Estra-1,3,5(10)-triene-3,16-alpha,17-beta-triol,3-benzoate, 16,17-diacetate 2508-47-6
Estra-1,3,5(10)-triene-1,3,17-triol, triacetate 2508-47-6
Estra-1,3,5(10)-triene-1,3,17-beta-triol, triacetate 4248-03-7
Estra-1,3,5(10)-triene-2,3,17-triol, triacetate 4248-03-7
Estra-1,3,5(10)-trien-3-ol 53-63-4
Estra-1,3,5(10)-trien-17-beta-ol,17-alpha-butadiynyl-3-methoxy- 1986-48-7
Estra-1,3,5(10)-trien-3-ol,17-alpha-(beta-D-glucopyranosyloxy)- 25517-69-5
Estra-1,3,5(10)-trien-3-ol, 17-mercapto- 25517-69-5
Estra-1,3,5(10)-trien-3-ol, 17-alpha-mercapto- 7438-72-4
Estra-1,3,5(10)-trien-17-ol, 3-methoxy- 94535-16-7
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 3-formyl-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate, O-(2-(4-methylpiperazinyl)ethyl)oxime 22912-78-3
Estra-1,3,5(10)-trien-17-beta-ol, 3-methoxy- 1035-77-4
Estra-1,3,5(10)-trien-17-ol, 3-methoxy-4-methyl- 1035-77-4
Estra-1,3,5(10)-trien-17-beta-ol, 3-methoxy-4-methyl- 4787-75-1
Estra-1,3,5(10)-trien-17-ol, 3-methoxy-,phenylcarbamate, (17-beta)- 43085-16-1
Estra-1,3,5(10)-trien-3-ol, 17-(methylthio)- 43085-16-1
Estra-1,3,5(10)-trien-3-ol, 17-beta-(methylthio)- 108619-67-6
Estra-1,3,5(10)-trien-3-ol,17-beta-(tetrahydro-2H-pyran-2-yloxy)- 3589-90-0
Estra-1,3,5(10)-trien-17-one 53-45-2
Estra-4,9,11-trien-3-one, 17-alpha-allyl-17-hydroxy- 850-52-2
Estra-1,3,5(10)-trien-17-one, 16-alpha-chloro- 20377-68-8
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 3-formyl-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate, O-(2-methyl prop-2-enyl)oxime 41970-69-8
Estra-1,3,5(10)-trien-17-one, dihydro-3-hydroxy- 41970-69-8
Estra-1,3,5(10)-trien-17-one, 1,3-dihydroxy- 60966-54-3
Estra-1,3,5(10)-trien-17-one, 3,4-dihydroxy- 3131-23-5
Estra-1,3,5(10)-trien-17-one, 1,4-dihydroxy-,diacetate 4147-06-2
Estra-4,9,11-trien-3-one, 17-beta-hydroxy- 10161-33-8
Estra-4,9,11-trien-3-one, 17-hydroxy-, (17-alpha)- 80657-17-6
Estra-4,9,11-trien-3-one, 17-beta-hydroxy-, acetate 10161-34-9

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