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MSDS  : Ferrate(2-), pentacyanonitrosyl-, disodium, dihydrate
CAS  : 13755-38-9
SYNONYMS  : * Disodium nitroprusside dihydrate * Ferrate(2-), pentakis(cyano-C)nitrosyl-, disodium, dihydrate (OC-6-22)-, * Nipride dihydrate * Nitroprussiate de sodium * Sodium nitroferricyanide dihydrate * Sodium nitroprussiate dihydrate * Sodium nitroprusside dihydrate * Sodium nitrosylpentacyanoferrate(III) dihydrate
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : LJ8925000
CHEMICAL NAME : Ferrate(2-), pentacyanonitrosyl-, disodium, dihydrate
CAS REGISTRY NUMBER : 13755-38-9
LAST UPDATED : 199707
DATA ITEMS CITED : 17
MOLECULAR FORMULA : C5-Fe-N6-O.2Na.2H2-O
MOLECULAR WEIGHT : 297.98
WISWESSER LINE NOTATION : NA2 FE-CN5-NO &QH 2
SYNONYMS/TRADE NAMES :
* Disodium nitroprusside dihydrate
* Ferrate(2-), pentakis(cyano-C)nitrosyl-, disodium, dihydrate (OC-6-22)-,
* Nipride dihydrate
* Nitroprussiate de sodium
* Sodium nitroferricyanide dihydrate
* Sodium nitroprussiate dihydrate
* Sodium nitroprusside dihydrate
* Sodium nitrosylpentacyanoferrate(III) dihydrate

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Human - child
DOSE/DURATION : 11700 ug/kg/60H-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified
REFERENCE :
CPEDAM Clinical Pediatrics (Philadelphia). (Lippincott/Harper, Journal
Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1962-
Volume(issue)/page/year: 31,380,1992

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 22,883,1980

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 7 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AANFAE Annales de l'Anesthesiologie Francaise. (Paris, France) V.1-22,
1960-81. Volume(issue)/page/year: 18(2),153,1977

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 9300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 29,1092,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 9 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AANFAE Annales de l'Anesthesiologie Francaise. (Paris, France) V.1-22,
1960-81. Volume(issue)/page/year: 18(2),153,1977

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 9500 ug/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 6 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AANFAE Annales de l'Anesthesiologie Francaise. (Paris, France) V.1-22,
1960-81. Volume(issue)/page/year: 18(2),153,1977

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 80 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 1 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 1 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 4800 ug/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 29,1092,1979

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Bird - pigeon
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Amphibian - frog
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - nausea or vomiting
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,480,1929

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X6152
No. of Facilities: 76 (estimated)
No. of Industries: 1
No. of Occupations: 3
No. of Employees: 1925 (estimated)
No. of Female Employees: 1358 (estimated)


*** END OF RECORD ***
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