MSDS   | : | Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-,
gamma-lactone, (11S)-
| CAS   | : | 481-06-1 | SYNONYMS   | : | * 11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone
* Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-, gamma-lactone,
(11S)-(-)-
* Naphtho(1,2-b)puran-2,8(3H,4H)-dione,
3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-
* Santonin
* alpha-Santonin
* L-alpha-Santonin
* Santoninic anhydride
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*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LE3150000
CHEMICAL NAME : Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-,
gamma-lactone, (11S)-
CAS REGISTRY NUMBER : 481-06-1
LAST UPDATED : 199701
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C15-H18-O3
MOLECULAR WEIGHT : 246.33
WISWESSER LINE NOTATION : T B566 COV LV IHTT&J E1 I1 M1
COMPOUND DESCRIPTOR : Human
Natural Product
SYNONYMS/TRADE NAMES :
* 11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone
* Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-, gamma-lactone,
(11S)-(-)-
* Naphtho(1,2-b)puran-2,8(3H,4H)-dione,
3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-
* Santonin
* alpha-Santonin
* L-alpha-Santonin
* Santoninic anhydride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human - man
DOSE/DURATION : 15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M.,
Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,301,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon
Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year:
52,79S,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#02213
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4536
No. of Facilities: 7 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 7 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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