*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LU3580000
CHEMICAL NAME : 2(3H)-Furanone, dihydro-5-methyl-
CAS REGISTRY NUMBER : 108-29-2
BEILSTEIN REFERENCE NO. : 0080420
REFERENCE : 5-17-09-00024 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C5-H8-O2
MOLECULAR WEIGHT : 100.13
WISWESSER LINE NOTATION : T5O CVTJ E1
COMPOUND DESCRIPTOR : Mutagen
Natural Product
Primary Irritant
SYNONYMS/TRADE NAMES :
* 4-Hydroxypentanoic acid lactone
* 4-Hydroxyvaleric acid lactone
* gamma-Methyl-gamma-butyrolactone
* 4-Methyl-gamma-butyrolactone
* gamma-Pentalactone
* 4-Pentanolide
* gamma-Valerolactone
* 4-Valerolactone
* gamma-Valerolakton
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
20,847,1982
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 8800 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 27,263,1945
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2480 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 27,263,1945
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
20,847,1982
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 76,189,1942
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/m3/7H/92D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)
V.18-31, 1936-49. For publisher information, see AEHLAU.
Volume(issue)/page/year: 27,263,1945
** MUTATION DATA **
TYPE OF TEST : Sex chromosome loss and nondisjunction
TEST SYSTEM : Yeast - Saccharomyces cerevisiae
DOSE/DURATION : 24400 ppm
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 201,431,1988
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
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Galphimia glauca Cav., extractSUBSTANCE DEFINITION :Plant belonging to the family MalpighiaceaeREFERENCE :CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,1255 Howard St., San Francisco, CA 94103) V.6- 1958-Volume(issue)/page/year: 13,882,1965
| 12063-98-8 |
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Gama-bufotoxin
| 53915-36-9 |
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Gamba A
| 60267-40-5 |
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Gambier tannin
| 60267-40-5 |
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Gamedin
| 60267-40-5 |
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Gancidin (unpurified)SUBSTANCE DEFINITION :Produced by the strain Streptomyces sp. AAK-84REFERENCE :85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,eds., Washington, DC, American Soc. for Microbiology, 1978Volume(issue)/page/year: 2,1354,1978
| 60267-40-5 |
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Gancidin A
| 101516-90-9 |
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Gangtokumycin
| 37220-69-2 |
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2(3H)-Furanone, dihydro-5-methyl-
| 108-29-2 |
|
Ganmeiling InjectionSUBSTANCE DEFINITION :Extract of roots of Sophora subprostrata Chun et T.Chen and Astragalusmembranaceus (Fisch.) Bge. var. mongholicus(Bge.) Hsiao(A. mongholicus Bge.)REFERENCE :CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (ChinaInternational Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-1980- Volume(issue)/page/year: 21,543,1990
| 108-29-2 |
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Ganmycin
| 64045-96-1 |
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Ganoderma lucidum (leys. exfr) Karst., extract
| 64045-96-1 |
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Garbhanivarana aushadamSUBSTANCE DEFINITION :An Indian antifertility agent composed of Piper longum, Embelia ribes andboraxREFERENCE :IJMRAQ Indian Journal of Medical Research. (Indian Council of MedicalResearch, Ansari Nagar, New Delhi 110 029, India) V.1- 1913-Volume(issue)/page/year: 64,959,1976
| 64045-96-1 |
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Garcinia anomala Planch. & Triana, extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family ClusiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 64045-96-1 |
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Garcinia cowa Roxb.ex DC., extractSUBSTANCE DEFINITION :Plant belonging to the family ClusiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 64045-96-1 |
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Garcinia indica Choisy, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family GuttiferaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 64045-96-1 |
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Garcinia lancifolia (G.Don.) Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family ClusiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 64045-96-1 |
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Garcinia livingstonii T. Ander., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family GuttiferaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 18,594,1980
| 64045-96-1 |
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Garcinia mangostana L., extractSUBSTANCE DEFINITION :Plant belonging to the family ClusiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 64045-96-1 |
|
2(3H)-Furanone, 4,5-dihydro-5-methyl-3-(2-propenyl)-
| 64045-96-1 |
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Garcinia polyantha Oliv., bark extractSUBSTANCE DEFINITION :Plant belonging to the family GuttiferaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:5,187,1982
| 64045-96-1 |
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Garcinia talbotii Raizada ex Santap., extractexcluding rootsSUBSTANCE DEFINITION :Plant belonging to the family GuttiferaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 64045-96-1 |
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Gardenia carinata Wall., extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,1255 Howard St., San Francisco, CA 94103) V.6- 1958-Volume(issue)/page/year: 13,882,1965
| 64045-96-1 |
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Gardenia gummifera Linn. f., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 64045-96-1 |
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Gardenia jasminoides Ellis., extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 64045-96-1 |
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Gardenia jasminoides, fruit extract
| 64045-96-1 |
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Gardenia lucida Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 64045-96-1 |
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Gardenia Yellow
| 94238-00-3 |
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Gardimycin
| 59165-34-3 |
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Gardneramine oxindole,1,2-didehydro-2-deoxo-17-deoxy-2,17-epoxy-
| 34274-91-4 |
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2(3H)-Furanone,dihydro-5-methyl-3-propyl-3-(2-pyridyl)-
| 71824-64-1 |
|
Gardneria ovata Wall., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family LoganiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 71824-64-1 |
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Garlic, extractSUBSTANCE DEFINITION :Extract obtained from Allium sativanREFERENCE :NUCADQ Nutrition and Cancer. (Franklin Institute Press, POB 2266,Phildelphia, PA 19103) V.1- 1978- Volume(issue)/page/year: 11,251,1988
| 71824-64-1 |
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Garlic oil
| 8000-78-0 |
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Garmala alkaloidsSUBSTANCE DEFINITION :A mixture of the alkaloids, including garmin and garmalin, extracted fromthe plant garmalaREFERENCE :VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga,113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 56(4),57,1980
| 8000-78-0 |
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Garryfoline, oxalate
| 63938-49-8 |
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Garryine, hydrochloride
| 6128-29-6 |
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Gas oil, blend
| 64741-44-2 |
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Gas oil, heavy IISUBSTANCE DEFINITION :A crude coal coprocessing productREFERENCE :JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., BaffinsLane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-Volume(issue)/page/year: 15,443,1995
| 64741-44-2 |
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Gas oils (petroleum), heavy vacuum
| 64741-57-7 |
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Gas oils (petroleum), hydrodesulfurized heavy vacuum
| 64742-86-5 |
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2(3H)-Furanone, dihydro-5-methyl-3-(2-pyridyl)-
| 41874-33-3 |
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Gas oils (petroleum), Light vacuum
| 64741-58-8 |
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Gas oils (petroleum), straight run
| 64741-43-1 |
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Gasoline
| 8006-61-9 |
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Gasoline engine exhaust fumes
| 8006-61-9 |
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Gasoline engine exhaust "tar"
| 8006-61-9 |
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Gasoline exhaust particles, crude extract
| 8006-61-9 |
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Gasoline, grade 100 aviation
| 8006-61-9 |
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Gasoline, unleaded
| 8006-61-9 |
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