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MSDS  : Glucaric acid, 1,46,3-dilactone, diacetate, D-
CAS  : 642-83-1
SYNONYMS  : * Aceglaton * Aceglatone * 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone * 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone * D-Glucaric acid di-gamma-lactone diacetate * D-Glucaric acid 1,4:6,3-dilactone diacetate * Glucaron
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : LZ3990000
CHEMICAL NAME : Glucaric acid, 1,4:6,3-dilactone, diacetate, D-
CAS REGISTRY NUMBER : 642-83-1
LAST UPDATED : 199103
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C10-H10-O8
MOLECULAR WEIGHT : 258.20
WISWESSER LINE NOTATION : T55 BOV FOVTJ DOV1 HOV1 -D,GLU
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Aceglaton
* Aceglatone
* 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone
* 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone
* D-Glucaric acid di-gamma-lactone diacetate
* D-Glucaric acid 1,4:6,3-dilactone diacetate
* Glucaron

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,14,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
11,5,1989

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,14,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,14,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,14,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,14,1982

*** END OF RECORD ***
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NAMECAS
Glochidion heyneanum Wall., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 15,208,1977 9007-83-4
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2(5H)-Furanone, 3-ethenyl-5-hydroxy-, calcium salt,hydrate (2:1:2) 9007-83-4
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Glochidion oblatum Hook.f., extractSUBSTANCE DEFINITION :Plant belonging to the family EuphorbiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990 9007-83-4
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Glucagon 9007-92-5
Glucagon, monohydrochloride 28270-04-4
D-Glucammonium,N-(3-acetamido-5-(methylcarbamoyl)-2,4,6-triiodobenzyl)-N-(2,3-dihydroxy propyl)-N-methyl-,(3-acetamido-5-methylcarbamoyl-2,4,6-triiodo)-,benzoate 71746-20-8
D-Glucammonium,N-(3-acetamido-5-(methylcarbamoyl)-2,4,6-triiodobenzyl)-N-(2,3-dihydroxy propyl)-N-methyl-, chloride 71746-11-7
2(5H)-Furanone, 5-ethyl- 2407-43-4
beta-D-Glucan, (1-3)- 9051-97-2
Glucanase, endo-1,3-beta- 9025-37-0
Glucaric acid, 1,46,3-dilactone, diacetate, D- 642-83-1
Glucitol 50-70-4
D-Glucaric acid, monopotassium salt 576-42-1
D-Glucitol,3-O-(4-(acetylamino)-4-deoxy-alpha-D-glucopyranosyl)-1,4-diamino-1,4-dideo xy- 60502-99-0
D-Glucitol,2-amino-1,4:3,6-dianhydro-2-deoxy-5-nitrate,monohydrochloride 81844-65-7
D-Glucitol,1,5-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(1-oxo-2,4-decadienyl)-beta-D-galactopyranosyl)-,3-(7-hydroxy-2,4,8,10-tetradecatetraenoate) 96989-32-1
D-Glucitol, bis-O-(phenylmethylene)- 32647-67-9
Glucitol, 6-chloro-6-deoxy- 76986-26-0
2(3H)-Furanone,dihydro-3-((bis(2-hydroxyethyl)amino)methyl)-5-(4-chlorophenyl)-, (Z)-2-butenedioate, hydrate (2:2:1)(salt) 124500-23-8
2(3H)-Furanone, 5-ethyldihydro- 695-06-7
D-Glucitol,2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-2-deoxy-, 1,3,4,5,6-pentaacetate 695-06-7
D-Glucitol,1-deoxy-1-((dithiocarboxy)(phenylmethyl)amino)-,monosodium salt, hydrate 102996-80-5
D-Glucitol, 1-deoxy-1-(methylamino)-,5-acetamido-N-(2-hydroxyethyl)-2,4,6-triiodoisophthalamate (salt) 29288-99-1
D-Glucitol, 1-deoxy-1-(methylamino)-,3-acetamido-5-(N-methylacetamido)-2,4,6-triiodobenzoate (salt) 7241-11-4
D-Glucitol, 1-deoxy-1-(methylamino)-,3-(acetamido)-2,4,6-triiodobenzoate (salt) 22154-43-4
D-Glucitol, 1-deoxy-1-(methylamino)-,3-(acetylamino)-5-((acetylamino)methyl)-2,4,6-triiodobenzoate (salt), mixt. with3-(acetylamino)-5-((acetylamino)methyl)-2,4,6-triiodobenzoic acid monosodium salt 58001-89-1
D-Glucitol, 1-deoxy-1-(methylamino)-,3-(acetylamino)-5-(((2-hydroxyethyl)amino)carbonyl)2,4,6-triiodobenzoate (salt), mixt. with3-(acetylamino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodobenzoic acid compd. with2-aminoethanol (1:1) 37244-86-3
D-Glucitol, 1-deoxy-1-(methylamino)-,3-(acetylamino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodobenzoate (salt), mixt. with3-(acetylamino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodobenzoic acid, monosodium salt 37244-85-2
D-Glucitol, 1-deoxy-1-(methylamino)-,3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)a mino)carbonyl)-2,4,6-triiodobenzoate (salt), mixt. with3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)a mino)carbonyl)-2,4,6-triiodobenzoic acid monosodium salt 76820-74-1
Glucitol, 1-deoxy-1-(methylamino)-,3,3'-(adipoyldiimino)bis(2,4,6-triiodobenzoate) (2:1)(salt), D- 3521-84-4
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- 27538-10-9
D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with4-amino-N-(3-methoxy-1-piperazinyl)benzenesulfonamide 62907-78-2
D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with4-amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide 53607-04-8
D-Glucitol, 1-deoxy-1-(methylamino)-,3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt)mixed with 3,5-bis(acetylamino)-2,4,6-triiodobenzoicacid monosodium salt 8064-12-8
D-Glucitol, 1-deoxy-1-(methylamino)-,(4-carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan-13-oato(5-)-N(sup 5),N(sup8),N(sup 11),O(sup 4),O(sup 5),O(sup 8), O(sup11),O(sup 13)-gadolinate(2-) (2:1) 127000-20-8
Glucitol, 1-deoxy-1-(methylamino)-,3,5-diacetamido-2,4,6-triiodobenzoate (salt), D- 131-49-7
Glucitol, 1-deoxy-1-(methylamino)-,alpha,5-diacetamido-2,4,6-triiodo-m-toluate (salt),D- 18656-21-8
D-Glucitol, 1-deoxy-1-(methylamino)-,3,3'-((1,6-dioxo-1,6-hexanediyl)diimino)bis(2,4,6-triiodo-5-((methylamino)carbonyl)benzoate) (2:1)(salt) 54605-45-7
D-Glucitol, 1-deoxy-1-(methylamino)-,3,3'-((1,16-dioxo-4,7,10,13-tetraoxahexadecane-1,16-diyl)diimino)bis(2,4,6-triiodobenzoate) (2:1)(salt) 51764-33-1
D-Glucitol, 1-deoxy-1-(methylamino)-,(R-(R*,R*))-4-((2-((3-(1H-indol-3-yl)-2-methyl-1-oxo-2-(((tricyclo(3.3.1.1(3,7))dec-2-yloxy)carbonyl)amino)propyl)amino)-1-phen ylethyl)amino)- 4-oxobutanoate(salt) 130404-91-0
D-Glucitol, 1-deoxy-1-(methylamino)-,2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylate (salt) 42461-84-7
2(5H)-Furanone, 5-ethylidene- 3690-50-4
D-Glucitol, 1-deoxy-1-(methylamino)-,3,3'-(oxybis(2,1-ethanediyloxy(1-oxo-2,1-ethanediyl)imino))bis(2,4,6-triiodobenzoate) (1:1) (salt) 72704-51-9
Glucitol, 1-deoxy-1-(methylamino)-,3,3'-(oxybis(methylenecarbonylimino))bis(2,4,6-triiodobenzoate) (2:1) (salt), D- 14317-18-1

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