RTECS NUMBER : LW1001000
CHEMICAL NAME : Gadolinate(2-),
(N,N-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5
-))-, dihydrogen, compd. with
1-deoxy-1-(methylamino)-D-glucitol (1:2)
CAS REGISTRY NUMBER : 86050-77-3
LAST UPDATED : 199412
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C14-H18-Gd-N3-O10.2C7-H17-N-O5.2H
MOLECULAR WEIGHT : 858.12
SYNONYMS/TRADE NAMES :
* Diethylenetriaminepentaacetic acid dimeglumine salt gadolinium chelate
* Dimeglumine-gadolinium-dtpa
* Magnevist
* Resovist
* SHL 451A
* ZK 93035
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 9411 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAJRDX AJR, American Journal of Roentgenology. (Williams & Wilkins Co., 428
E. Preston St., Baltimore, MD 21202) V.126- 1976-
Volume(issue)/page/year: 142,619,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 612 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAJRDX AJR, American Journal of Roentgenology. (Williams & Wilkins Co., 428
E. Preston St., Baltimore, MD 21202) V.126- 1976-
Volume(issue)/page/year: 142,619,1984
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4291 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year:
(Suppl),254,1992
*** END OF RECORD ***
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