*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AS8100000
CHEMICAL NAME : Acrylic acid, diester with tetraethylene glycol
CAS REGISTRY NUMBER : 17831-71-9
LAST UPDATED : 199803
DATA ITEMS CITED : 15
MOLECULAR FORMULA : C14-H22-O7
MOLECULAR WEIGHT : 302.36
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Acrylic acid, oxybis(ethyleneoxyethylene) ester
* Aronix M 240
* 2-Propenoic acid, oxybis(2,1-ethanediyloxy-2,1-ethanediyl)ester
* SR 268
* Tetraethylene glycol diacrylate
* Viscoat 335HP
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 19,149,1986
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg
REACTION SEVERITY : Severe
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 19,149,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 813 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
Behavioral - ataxia
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0534744
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 19,149,1986
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3 gm/kg/2W-I
TOXIC EFFECTS :
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0555406
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 16 gm/kg/80W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 19,149,1986
** MUTATION DATA **
TYPE OF TEST : Micronucleus test
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 2 mg/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,381,1989
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 2 mg/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,381,1989
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 2 mg/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,394,1989
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 2 mg/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,394,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - T1072
No. of Facilities: 17 (estimated)
No. of Industries: 2
No. of Occupations: 3
No. of Employees: 216 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - T1072
No. of Facilities: 196 (estimated)
No. of Industries: 7
No. of Occupations: 11
No. of Employees: 2082 (estimated)
No. of Female Employees: 405 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Acrylic acid, diester with tetraethylene glycol
| 17831-71-9 |
Acrylic acid, diester with triethylene glycol
| 1680-21-3 |
Acrylic acid,3-(o-((2-(diethylamino)ethyl)carbamoyl)phenyl)-2-hydroxy-3-phenyl-
| 112393-00-7 |
Acrylic acid, 2-(diethylamino)ethyl ester
| 2426-54-2 |
Acrylic acid, 3-(dimethylamino)-, ethyl ester, (E)-
| 1117-37-9 |
Acrylic acid,2-(diethylaminomethyl)-3,3-di-2-thienyl-, ethylester, picrolonate
| 1117-37-9 |
9-Acridinamine, 1,2,3,4-tetrahydro-N-hexyl-,monohydrochloride
| 113106-03-9 |
Acrylic acid,3-(o-((3-(diethylamino)propyl)carbamoyl)phenyl)-2-hydroxy-3-phenyl-
| 112392-98-0 |
Acrylic acid, 3,3-difluoro-2-(trifluoromethyl)-,methyl ester
| 685-09-6 |
Acrylic acid,3-(o-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-2-hydroxy-3-phenyl-
| 112393-01-8 |
Acrylic acid, 2-(dimethylamino)ethyl ester
| 2439-35-2 |
Acrylic acid,2-(dimethylaminomethyl)-3,3-di-2-thienyl-, ethylester, picrate
| 102751-39-3 |
Acrylic acid,3-(o-((3-(dimethylamino)propyl)carbamoyl)phenyl)-2-hydroxy-3-phenyl-
| 112392-99-1 |
Acrylic acid,3-((5,5-dimethyl-2-oxotetrahydro-3-furyl)carbamoyl)-,ethyl ester
| 101952-45-8 |
Acrylic acid, 2,2-dimethyltrimethylene ester
| 2223-82-7 |
Acrylic acid, 3,3-diphenyl-
| 606-84-8 |
Acrylic acid, 3,3-diphenyl-, 2-diethylaminoethylester
| 101952-46-9 |
9-Acridinamine, 1,2,3,4-tetrahydro-N-methyl-
| 316-88-1 |
Acrylic acid, 3,3-diphenyl-, 2'-(diethylamino)ethylester, hydrochloride
| 5449-57-0 |
Acrylic acid, 2,3-epoxypropyl ester
| 106-90-1 |
Acrylic acid, ester with ethyl glycolate
| 21045-68-1 |
Acrylic acid, 2-ethoxyethanol diester
| 4074-88-8 |
Acrylic acid, 2-ethoxyethyl ester
| 106-74-1 |
Acrylic acid, ethoxypropyl ester
| 64050-15-3 |
Acrylic acid, 2-ethylbutyl ester
| 3953-10-4 |
Acrylic acid, ethylene ester
| 2274-11-5 |
Acrylic acid, ethyl ester
| 140-88-5 |
Acrylic acid, 2-ethylhexyl ester
| 103-11-7 |
9-Acridinamine,1,2,3,4-tetrahydro-N-(1-methylhexyl)-,monohydrochloride
| 113106-72-2 |
Acrylic acid, ethylhexyl ester mixed withhydroxyethyl ester (50:50)
| 113106-72-2 |
Acrylic acid, 2-(5'-ethylpyrid-2'-yl)ethyl ester
| 122-93-0 |
Acrylic acid, 3-(ethylsulfonyl)-, ethyl ester
| 73663-91-9 |
Acrylic acid, 2-(ethylthio)ethyl ester
| 15205-68-2 |
Acrylic acid, 3-(2-furyl)-2-phenyl-,2-(diethylamino)ethyl ester, hydrochloride
| 66922-76-7 |
Acrylic acid, heptyl ester
| 2499-58-3 |
Acrylic acid, hexamethylene ester
| 13048-33-4 |
Acrylic acid, hexyl ester
| 2499-95-8 |
Acrylic acid, ester with hydracrylonitrile
| 106-71-8 |
Acrylic acid, 2-hydroxyethyl ester
| 818-61-1 |
Acridan, 9,9-dimethyl-10-(3-(dimethylamino)propyl)-
| 4757-55-5 |
9-Acridinamine,1,2,3,4-tetrahydro-7-methyl-N-(2-methylpropyl)-
| 34811-15-9 |
Acrylic acid, 2-(hydroxymethyl)-, ethyl ester
| 10029-04-6 |
Acrylic acid, 3-hydroxy-2-methyl-, methyl ester,ester with dimethyl phosphorothioate
| 30864-28-9 |
Acrylic acid,2-hydroxy-3-(o-((2-morpholinoethyl)carbamoyl)phenyl)-3-phenyl-
| 112392-96-8 |
Acrylic acid,2-hydroxy-3-phenyl-3-(o-((2-(1-pyrrolidinyl)ethyl)carbamoyl)phenyl)-
| 112392-97-9 |
Acrylic acid, 2-hydroxypropyl ester
| 999-61-1 |
Acrylic acid, 3-iodo-, sodium salt, (Z)-
| 73663-92-0 |
Acrylic acid, isobutyl ester
| 106-63-8 |
Acrylic acid, 2-(isobutyl-(ONN)azoxy)-
| 101961-60-8 |
Acrylic acid, isodecyl ester
| 1330-61-6 |
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