RTECS NUMBER : MI8900000
CHEMICAL NAME : Heptane, 1,2:6,7-diepoxy-
CAS REGISTRY NUMBER : 4247-19-2
BEILSTEIN REFERENCE NO. : 0104311
REFERENCE : 4-19-00-00125 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C7-H12-O2
MOLECULAR WEIGHT : 128.19
WISWESSER LINE NOTATION : T3OTJ B3- BT3OTJ
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* 1,2:6,7-Diepoxyheptane
* Oxirane, 2,2'-(1,3-propanediyl)bis-
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2400 mg/kg/20W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60,
1940-78. For publisher information, see JJIND8. Volume(issue)/page/year:
35,707,1965
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 7560 mg/kg/63W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
REFERENCE :
14JTAF "Mycotoxins in Foodstuffs, Proceedings of the Symposium held at the
Massachusetts Institute of Technology, 1964," Wogan, G.N., ed., Cambridge,
MA, MIT Press, 1965 Volume(issue)/page/year: -,275,1965
*** END OF RECORD ***
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