*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : MG1019000
CHEMICAL NAME : Gunacin
CAS REGISTRY NUMBER : 73341-70-5
BEILSTEIN REFERENCE NO. : 1332129
REFERENCE : 5-18-05-00435 (Beilstein Handbook Reference)
LAST UPDATED : 199806
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C17-H16-O8
MOLECULAR WEIGHT : 348.33
WISWESSER LINE NOTATION : T C666 BV DO IVT&&J E1 FQ GOV1 KQ MO1
COMPOUND DESCRIPTOR : Drug
Mutagen
Natural Product
SYNONYMS/TRADE NAMES :
* 2H-Naphtho(2,3-b)pyran-5,10-dione,
3,4-dihydro-4-(acetyloxy)-3,6-dihydroxy-8-methoxy-2-methyl-
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 16 mg/kg
TOXIC EFFECTS :
Behavioral - irritability
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 32,1104,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12 mg/kg
TOXIC EFFECTS :
Behavioral - irritability
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 32,1104,1979
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2100 mg/kg/21D-I
TOXIC EFFECTS :
Endocrine - other changes
Blood - changes in spleen
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
REFERENCE :
JPTLAS Journal of Pathology. (John Wiley & Sons, Inc., 605 Third Ave., New
York, NY 10158) V.97- 1969- Volume(issue)/page/year: 138,163,1982
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 200 ug/L
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 32,1104,1979
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Guanosine
| 118-00-3 |
Guanosine, 2'-amino-2'-deoxy-
| 60966-26-9 |
Guanosine,2'-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-2'-deoxy-
| 70865-71-3 |
Guanosine,2'-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-2'-deoxy-N-((dimethylami no) methylene)-
| 70865-76-8 |
Guanidine,N-(1,1-dimethylethyl)-N'-2-pyridinyl-N''-2-thiazolyl-, mononitrate
| 72041-79-3 |
Guanosine, 2'-deoxy-
| 961-07-9 |
Guanosine,2'-deoxy-N-((dimethylamino)methylene)-2'-(((methylnitrosoamino)carbonyl)am ino)-
| 70865-75-7 |
Guanosine,2'-deoxy-2'-(((methylnitrosoamino)carbonyl)amino)-
| 66779-33-7 |
Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate)
| 2564-35-4 |
Guanosine,2'-deoxy-P-thioadenylyl-(5'-3')-2'-deoxy-P-thiocytidylyl-(5'-3')-P-thiothy midylyl-(5'-3')-P-thiothymidylyl-(5'-3')-P-thiothymidylyl(5'-3')-2'-deoxy-P-thiogu anylyl-(5'-3')-2'-deoxy-P-thioadenylyl-(5'-3')-2'-deoxy-P-thioguanylyl-(5'-3')-P-thiothym idylyl-(5'-3')-2'-deoxy-P-thioguanylyl-(5'-3')-2'-deoxy-P-thioguanylyl-(5'-3')-P-thiothymidy lyl-(5'-3')-2'-deoxy-P-thiocytidylyl-(5'-3')-2'-deoxy-P-thioguanylyl-(5'-3')-2'-deoxy-P-t hiocytidylyl-(5'-3')-P-thiothymidylyl-(5'-3')-2'-deoxy-P-thiocytidylyl-(5'-3')-P-thioth ymidylyl-(5'-3')-P-thiothymidylyl-(5'-3')-2'-deoxy-
| 151879-73-1 |
Guanosine, O-methyl-
| 7803-88-5 |
Guanosine, 5'-(tetrahydrogen triphosphate)
| 86-01-1 |
5'-Guanylic acid
| 85-32-5 |
5'-Guanylic acid, disodium salt
| 5550-12-9 |
Glycine,N-((4,5-dihydro-3-phenyl-5-isoxazolyl)ethoxyphosphinyl)-, phenylmethyl ester
| 125674-72-8 |
Guanidine,1-((3,4-dihydro-2H-1,5-benzodioxepin-7-yl)methyl)-,sulfate (2:1)
| 23474-99-9 |
Guanidine,N-(1,1-dimethylethyl)-N'-2-quinolinyl-N''-2-thiazolyl-
| 72041-89-5 |
Glycine,N-((4,5-dihydro-3-phenyl-5-isoxazolyl)methylphosphinyl)-, phenylmethyl ester
| 125674-73-9 |
3'-Guanylic acid, N(sup 2)-(2-hydroxy-3-oxopropenyl)-
| 75608-25-2 |
5'-Guanylic acid, N(sup 2)-(2-hydroxy-3-oxopropenyl)-
| 75608-23-0 |
5'-Guanylic acid, 7-oxide, disodium salt,pentahydrate
| 129136-59-0 |
5'-Guanylic acid, polymers, complex with 5'-cytidylicacid polymers (1:1)
| 25280-45-9 |
Guarea thompsonii Sprague et Hutch., bark extractSUBSTANCE DEFINITION :Plant belonging to the family MeliaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:5,187,1982
| 25280-45-9 |
Guar gum
| 9000-30-0 |
Guar gum, carboxymethyl ether, sodium salt
| 39346-76-4 |
Guar gum, hydrogen sulfate, sodium salt
| 37219-95-7 |
Guar gum, 2-hydroxypropyl2-hydroxy-3-(trimethylammonio)propyl ester, chloride
| 71329-50-5 |
Guanidine,N-(1,1-dimethylethyl)-N'-3-quinolinyl-N''-2-thiazolyl-
| 72041-90-8 |
Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether,chloride
| 65497-29-2 |
GuavaSUBSTANCE DEFINITION :Material extracted with hot water from the unripe fruits of P. guajavaREFERENCE :JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60,1940-78. For publisher information, see JJIND8.
| 65497-29-2 |
Guazatine
| 108173-90-6 |
Guazuma tomentosa Kunth, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family SterculiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 108173-90-6 |
Gudakhu, extractedSUBSTANCE DEFINITION :Paste-like tobacco preparation used widely in Orissa, IndiaREFERENCE :MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AEAmsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 280,45,1992
| 108173-90-6 |
Guettarda andamanica Goel & Mehrotra, extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 108173-90-6 |
Guettarda speciosa Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 108173-90-6 |
Guibourtia demeusei (harms) J. Leonard, bark extractSUBSTANCE DEFINITION :Plant belonging to the family CesalpiiaceaeREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:5,187,1982
| 108173-90-6 |
Guilingii wine
| 108173-90-6 |
Gui Lu preparation
| 108173-90-6 |
Guanidine,N-(1,1-dimethylethyl)-N'-4-quinolinyl-N''-2-thiazolyl-
| 71079-91-9 |
Guizotia scabra (Juis.) Chiov, extractSUBSTANCE DEFINITION :African plant belonging to the family AsteraceesREFERENCE :JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. IrelandLtd., POB 85, Limerick, Ireland) V.1- 1979-
| 71079-91-9 |
Gum tara
| 39300-88-4 |
Gunacin
| 73341-70-5 |
Gurjun balsam
| 8030-55-5 |
Gutierrezia microcephala, leaf
| 8030-55-5 |
alpha-2-Guttiferin
| 11048-92-3 |
GV-523SUBSTANCE DEFINITION :Polyethylene glycol-treated human immunoglobulinREFERENCE :OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,887,1983
| 11048-92-3 |
Gymnema montanum Hk. f., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family AsclepiadaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 11048-92-3 |
Gymnema sylvestre Robr., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family AsclepiadaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 11048-92-3 |
Gymnemic acid A1
| 11035-38-4 |
Guanidine,N-(1,1-dimethylethyl)-N'-5-quinolinyl-N''-2-thiazolyl-
| 72041-92-0 |
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