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MSDS  : Lauric acid
CAS  : 143-07-7
SYNONYMS  : * C-1297 * Dodecanoic acid * n-Dodecanoic acid * Dodecoic acid * Duodecylic acid * Hydrofol acid 1255 * Hydrofol acid 1295 * Hystrene 9512 * Laurostearic acid * Neo-fat 12 * Neo-fat 12-43 * Ninol AA62 Extra * 1-Undecanecarboxylic acid * Wecoline 1295
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OE9800000
CHEMICAL NAME : Lauric acid
CAS REGISTRY NUMBER : 143-07-7
BEILSTEIN REFERENCE NO. : 1099477
REFERENCE : 4-02-00-01082 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C12-H24-O2
MOLECULAR WEIGHT : 200.36
WISWESSER LINE NOTATION : QV11
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Natural Product
Primary Irritant
SYNONYMS/TRADE NAMES :
* C-1297
* Dodecanoic acid
* n-Dodecanoic acid
* Dodecoic acid
* Duodecylic acid
* Hydrofol acid 1255
* Hydrofol acid 1295
* Hystrene 9512
* Laurostearic acid
* Neo-fat 12
* Neo-fat 12-43
* Ninol AA62 Extra
* 1-Undecanecarboxylic acid
* Wecoline 1295

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Mild
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 6(3),321,1987

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg
REACTION SEVERITY : Mild
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 6(3),321,1987

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FDRLI* Food & Drug Research Laboratories, Inc., Papers. (P.O. Box 107, Rt.
17C, Waverly, NY 14892-0107) Volume(issue)/page/year: 123,-,1976

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 131 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
18,141,1961

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 333 gm/kg/13W-C
TOXIC EFFECTS :
Behavioral - food intake (animal)
Behavioral - fluid intake
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 16,519,1978

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 108 gm/kg/15W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - active as anti-cancer agent
REFERENCE :
APMIAL Acta Pathologica et Microbiologica Scandinavica. (Copenhagen,
Denmark) V.1-77, 1924-69. For publisher information, see ACPADQ.
Volume(issue)/page/year: 46,51,1959

** MUTATION DATA **

TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Yeast - Saccharomyces cerevisiae
DOSE/DURATION : 10 mg/L
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 294,263,1981

*** REVIEWS ***

TOXICOLOGY REVIEW
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60.
For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84696
No. of Facilities: 1256 (estimated)
No. of Industries: 14
No. of Occupations: 34
No. of Employees: 14960 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84696
No. of Facilities: 4690 (estimated)
No. of Industries: 51
No. of Occupations: 50
No. of Employees: 77970 (estimated)
No. of Female Employees: 17300 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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