*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OE9800000
CHEMICAL NAME : Lauric acid
CAS REGISTRY NUMBER : 143-07-7
BEILSTEIN REFERENCE NO. : 1099477
REFERENCE : 4-02-00-01082 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C12-H24-O2
MOLECULAR WEIGHT : 200.36
WISWESSER LINE NOTATION : QV11
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Natural Product
Primary Irritant
SYNONYMS/TRADE NAMES :
* C-1297
* Dodecanoic acid
* n-Dodecanoic acid
* Dodecoic acid
* Duodecylic acid
* Hydrofol acid 1255
* Hydrofol acid 1295
* Hystrene 9512
* Laurostearic acid
* Neo-fat 12
* Neo-fat 12-43
* Ninol AA62 Extra
* 1-Undecanecarboxylic acid
* Wecoline 1295
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg
REACTION SEVERITY : Mild
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 6(3),321,1987
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg
REACTION SEVERITY : Mild
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 6(3),321,1987
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FDRLI* Food & Drug Research Laboratories, Inc., Papers. (P.O. Box 107, Rt.
17C, Waverly, NY 14892-0107) Volume(issue)/page/year: 123,-,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 131 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
18,141,1961
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 333 gm/kg/13W-C
TOXIC EFFECTS :
Behavioral - food intake (animal)
Behavioral - fluid intake
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 16,519,1978
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 108 gm/kg/15W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - active as anti-cancer agent
REFERENCE :
APMIAL Acta Pathologica et Microbiologica Scandinavica. (Copenhagen,
Denmark) V.1-77, 1924-69. For publisher information, see ACPADQ.
Volume(issue)/page/year: 46,51,1959
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Yeast - Saccharomyces cerevisiae
DOSE/DURATION : 10 mg/L
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 294,263,1981
*** REVIEWS ***
TOXICOLOGY REVIEW
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60.
For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84696
No. of Facilities: 1256 (estimated)
No. of Industries: 14
No. of Occupations: 34
No. of Employees: 14960 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84696
No. of Facilities: 4690 (estimated)
No. of Industries: 51
No. of Occupations: 50
No. of Employees: 77970 (estimated)
No. of Female Employees: 17300 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Laprol 62
| 101858-08-6 |
Laprol 64
| 12609-02-8 |
Laprol 702
| 25322-69-4 |
Laprol 1601-2-50
| 61036-35-9 |
Laprol 3203-4-80
| 64925-45-7 |
Laprol 402-2-100
| 64925-45-7 |
Laprol 1601-2-50M
| 53857-92-4 |
Laqurelen 1003SUBSTANCE DEFINITION :Copolymer of butylacrylate, methacrylic acid dissolved in butylacetateREFERENCE :GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/OMezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-Volume(issue)/page/year: 52(9),92,1987
| 53857-92-4 |
Juniperus squamata Ham. ex Lambart, extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family PinaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 53857-92-4 |
Laraha
| 53857-92-4 |
Larch arabogalactan ISUBSTANCE DEFINITION :A water soluble polysaccharide from the stems of Larix occidentalisREFERENCE :JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc.,2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
| 53857-92-4 |
Largomycin
| 79748-87-1 |
Largomycin F II
| 94188-54-2 |
Lashiosphaera fenzli Reich, crude extract
| 94188-54-2 |
Lasia aculeata Lour., extractSUBSTANCE DEFINITION :Plant belonging to the family AraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 94188-54-2 |
Lasianthus venulosus (wt. & Arn.) Wt., extractexcluding rootsSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 94188-54-2 |
Lasiocarpine
| 303-34-4 |
Lasiocarpine, didehydro-
| 23092-98-0 |
Lasiocarpine N-oxide
| 127-30-0 |
Junus Green
| 127-30-0 |
Lasiosiphon kraussianus, root extract
| 127-30-0 |
Laspartomycin
| 12676-61-8 |
Lassia aculeata Lour., rhizome extractSUBSTANCE DEFINITION :Plant belonging to the family AraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 12676-61-8 |
Lateriomycin A
| 37248-16-1 |
Lateriomycin B
| 37248-17-2 |
Lateriomycin F
| 56274-05-6 |
Laterosporamine
| 59978-76-6 |
Lathyrus aphaca Linn., seed extractSUBSTANCE DEFINITION :Plant belonging to the family LeguminosaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 59978-76-6 |
Lathyrus sativus, leaf extract
| 59978-76-6 |
Lathyrus sativus, seed extract
| 92128-86-4 |
Jurinea macrocephala (DC.)Benth., extractSUBSTANCE DEFINITION :Plant belonging to the family AsteraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 92128-86-4 |
Laticotoxin A
| 50926-20-0 |
alpha-Latrotoxin
| 65988-34-3 |
Latrunculia corticata, extractSUBSTANCE DEFINITION :Extracted from a marine spongeREFERENCE :TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,UK) V.1- 1962- Volume(issue)/page/year: 23,955,1985
| 65988-34-3 |
Launaea nudicaulis Hook.f., extractSUBSTANCE DEFINITION :Plant belonging to the family CompositaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 7,250,1969
| 65988-34-3 |
Launaea resedifolia (Linn.) O. Ktze., extractSUBSTANCE DEFINITION :Plant belonging to the family AsteraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 65988-34-3 |
Lauraldehyde, (5-nitro-2-pyridyl)hydrazone
| 28058-07-3 |
Lauramidine, hydrochloride
| 28058-07-3 |
Laurelia sempervirens R. et pav., extractSUBSTANCE DEFINITION :Plant belonging to the family MonimiaceaeREFERENCE :PHYREH Phytotherapy Research. (Heyden & Son Ltd., Spectrum House, HillviewGardens, London, NW4 2JQ, UK) V.1- 1987-
| 28058-07-3 |
Laurel leaf oil
| 28058-07-3 |
Lauric acid
| 143-07-7 |
Jussiaea repens Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family OnagraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 143-07-7 |
Lauric acid, barium cadmium salt
| 15337-60-7 |
Lauric acid, cadmium salt (21)
| 2605-44-9 |
Lauric acid, 2-chloro-3,11-dimethyl-3-hydroxy-,sodium salt
| 57272-22-7 |
Lauric acid, 2-chloro-3,7,11-trimethyl-, sodium salt
| 57272-19-2 |
Lauric acid, 2-cyano-3,7,11-trimethyl-, sodium salt
| 57272-21-6 |
Lauric acid, 4,6-dinitro-o-tolyl ester
| 57272-21-6 |
Lauric acid, 2,3-epoxypropyl ester
| 1984-77-6 |
Lauric acid, 9a-ester with1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-decahydro-3-(hydroxymethyl)-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-1,1,6,8-alph a-tetramethyl-5H-cyclopropa(3,4)benz(1,2-e)azulen-5-one 9-acetate
| 20839-16-1 |
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