RTECS NUMBER : OL5975000
CHEMICAL NAME : Lysol
CAS REGISTRY NUMBER : 12772-68-8
LAST UPDATED : 199712
DATA ITEMS CITED : 8
COMPOUND DESCRIPTOR : Human
Primary Irritant
SYNONYMS/TRADE NAMES :
* CP 99325
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 uL/24H
REACTION SEVERITY : Severe
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0538621
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Vascular - relaxation (isolated tissues)
Lungs, Thorax, or Respiration - other changes
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
REFERENCE :
WILEAR Wiadomosci Lekarskie. Medical News. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.1- 1948- Volume(issue)/page/year: 27,1211,1974
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Kidney, Ureter, Bladder - urine volume decreased
Nutritional and Gross Metabolic - metabolic acidosis
REFERENCE :
WILEAR Wiadomosci Lekarskie. Medical News. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.1- 1948- Volume(issue)/page/year: 27,1211,1974
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Behavioral - coma
Gastrointestinal - other changes
REFERENCE :
BEGMA5 Beitraege zur Gerichtlichen Medizin. (Verlag Franz Deuticke,
Helferstorferstr 4, A-1010 Vienna, Austria) V.1- 1911-
Volume(issue)/page/year: 13,56,1935
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 43315
No. of Facilities: 12160 (estimated)
No. of Industries: 55
No. of Occupations: 39
No. of Employees: 68587 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 43315
No. of Facilities: 1080 (estimated)
No. of Industries: 17
No. of Occupations: 11
No. of Employees: 7802 (estimated)
No. of Female Employees: 2922 (estimated)