*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OI6180000
CHEMICAL NAME : Ligroine
CAS REGISTRY NUMBER : 8032-32-4
OTHER CAS REGISTRY NOS. : 8031-06-9
LAST UPDATED : 199712
DATA ITEMS CITED : 18
COMPOUND DESCRIPTOR : Reproductive Effector
Primary Irritant
SYNONYMS/TRADE NAMES :
* Benzine (light petroleum distillate)
* Benzoline
* Canadol
* Ligroin
* Painters naphtha
* Petroleum ether
* Refined solvent naphtha
* Skellysolve F
* Skellysolve G
* Varnish marker's naphtha
* VM and P Naphtha
* VM & P Naphtha
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Human
DOSE/DURATION : 880 ppm/15M
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
32,263,1975
** ACUTE TOXICITY DATA **
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3400 ppm/4H
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle weakness
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
32,263,1975
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 153 gm/m3/31M
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - changes in motor activity (specific assay)
REFERENCE :
BIZEA2 Biochemische Zeitschrift. (Berlin, Ger.) V.1-346, 1906-67. For
publisher information, see EJBCAI. Volume(issue)/page/year: 115,235,1921
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation
of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1-
1967- Volume(issue)/page/year: 7,765,1973
** REPRODUCTIVE DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE : 300 mg/m3/4H
SEX/DURATION : female 1-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
Reproductive - Effects on Newborn - behavioral
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 56(9),35,1991
*** REVIEWS ***
ACGIH TLV-Animal carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 1370 mg/m3 (300 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO VM & P NAPHTHA-air:10H TWA 350 mg/m3;CL 1800 mg/m3/15M
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M0630
No. of Facilities: 1437 (estimated)
No. of Industries: 21
No. of Occupations: 22
No. of Employees: 10998 (estimated)
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2829
No. of Facilities: 182022 (estimated)
No. of Industries: 459
No. of Occupations: 231
No. of Employees: 2414497 (estimated)
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - T0180
No. of Facilities: 1133 (estimated)
No. of Industries: 16
No. of Occupations: 12
No. of Employees: 3524 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M0630
No. of Facilities: 5 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 1674 (estimated)
No. of Female Employees: 109 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - T0180
No. of Facilities: 93614 (estimated)
No. of Industries: 337
No. of Occupations: 196
No. of Employees: 1319179 (estimated)
No. of Female Employees: 164513 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NIOSH Analytical Method, 1994: Naphthas, 1550
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Magnesium sulfate (11)
| 7487-88-9 |
Magnesium(II), sulfate, heptahydrate
| 10034-99-8 |
Magnesium thiosulfate hexahydrate
| 13446-30-5 |
Magnesium(2+), tris(octamethylpyrophosphoramide)-,diperchlorate
| 15604-80-5 |
Magnetic luminescent paste, ML-1
| 15604-80-5 |
Magnetite
| 1309-38-2 |
Magnolia grandiflora L., extractSUBSTANCE DEFINITION :Plant belonging to the family MagnoliaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 1309-38-2 |
Lignosulfonic acid, sodium salt
| 8061-51-6 |
Magnolia hodgsonii (Hook.f.& Thoms.)Keng, extractSUBSTANCE DEFINITION :Plant belonging to the family MagnoliaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8061-51-6 |
Magnopeptin
| 9063-87-0 |
Maharanga emodi (wall) DC., extractSUBSTANCE DEFINITION :Plant belonging to the family BoraginaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 9063-87-0 |
Mahogany wood smoke condensateSUBSTANCE DEFINITION :Smoke condensate of wood used for food preservation/aromatization in NigeriaREFERENCE :MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AEAmsterdam, Netherlands) V.1- 1964-
| 9063-87-0 |
Mahonia fortunei Fedde, stem extractSUBSTANCE DEFINITION :Plant containing berberine-type alkaloidsREFERENCE :YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-Volume(issue)/page/year: 82,726,1962
| 9063-87-0 |
Mahonia japonica DC., extractSUBSTANCE DEFINITION :Plant containing berberine-type alkaloidsREFERENCE :YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-Volume(issue)/page/year: 82,726,1962
| 9063-87-0 |
Mahonia leschenaultii Takeda, extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family BerberidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 9063-87-0 |
Mahonia napaulensis DC., root extractSUBSTANCE DEFINITION :Plant belonging to the family BerberidaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 7,250,1969
| 9063-87-0 |
Ma-huangSUBSTANCE DEFINITION :Chinese Ephedra herbal preparation containing 9% l-ephedrineREFERENCE :TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 30,111,1996
| 9063-87-0 |
Maitotoxin
| 59392-53-9 |
Ligrasol
| 71343-75-4 |
Maitotoxin, didesulfo-
| 71343-75-4 |
Maitotoxin, monodesulfo-
| 71343-75-4 |
Maize color
| 71343-75-4 |
MAK
| 39444-61-6 |
Makinenite
| 12201-85-3 |
Maleamic acid,N-(5-carboxymethyl-4-(p-chlorophenyl)-2-thiazolyl)-
| 74241-18-2 |
Maleamic acid,N-(5-carboxymethyl-4-(p-chlorophenyl)-2-thiazolyl)-,5'-methyl ester
| 74241-17-1 |
Maleamic acid, N-(3-isopropoxypropyl)-
| 73747-58-7 |
Maleamic acid, N-(5-methyl-1,3,4-thiadiazol-2-yl)-
| 73747-58-7 |
Maleamic acid, N-(4-phenyl-2-thiazolyl)-
| 73747-58-7 |
Ligroine
| 8032-32-4 |
Maleic acid
| 110-16-7 |
Maleic acid, bis(1,3-dimethylbutyl) ester
| 105-52-2 |
Maleic acid, bis(2-ethylhexyl) ester
| 142-16-5 |
Maleic acid, bis(2-methoxyethyl) ester
| 10232-93-6 |
Maleic acid, chloro-, bis(2-chloroethyl) ester
| 63917-05-5 |
Maleic acid, chloro-, dimethyl ester
| 19393-45-4 |
Maleic acid, diallyl ester
| 999-21-3 |
Maleic acid, dibutyl ester
| 105-76-0 |
Maleic acid, di(2-chloroethyl) ester
| 63917-06-6 |
Maleic acid, didecyl ester
| 45298-06-4 |
Ligularia sibirica (L. f.) Cass. var. racemosa (DC.)Kitam., extractSUBSTANCE DEFINITION :Plant belonging to the family AsteraceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 45298-06-4 |
Maleic acid, diethyl ester
| 141-05-9 |
Maleic acid, diisopropyl ester
| 10099-70-4 |
Maleic acid, dioctyl ester
| 2915-53-9 |
Maleic acid, dipentyl ester
| 10099-71-5 |
Maleic acid, disodium salt
| 371-47-1 |
Maleic acid, 2-hydroxyethyl ester, ester with(beta-methylphenethyl) carbamic acid monosodium salt
| 371-47-1 |
Maleic acid, mercapto-, dimethyl ester, S-ester withO,O-diethyl phosphorodithioate
| 63917-07-7 |
Maleic acid, monoethyl ester, sodium salt
| 63917-07-7 |
Maleic acid, mono(2-(2-hydroxyethoxy)ethyl) ester
| 10099-72-6 |
|
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