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MSDS  : Mercury, (3-(((3-carboxy-2,2,3-trimethylcyclopentyl)carbonyl)a mino)-2-methoxypropyl) (mercaptoacetato-S)-, disodium salt
CAS  : 21259-76-7
SYNONYMS  : * N-(gamma-Carboxymethylmercaptomercuri-beta-methoxy)propylcamphoramic acid disodium salt * Disodium N-(3-(carboxymethylthiomercuri)-2-methoxypropyl)-alpha-camphoramate * Diucardyn sodium * Mercaptomerin sodium * Sodium mercaptomerin * Thiomerin sodium
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OV8700000
CHEMICAL NAME : Mercury,
(3-(((3-carboxy-2,2,3-trimethylcyclopentyl)carbonyl)a
mino)-2-methoxypropyl) (mercaptoacetato-S)-, disodium
salt
CAS REGISTRY NUMBER : 21259-76-7
LAST UPDATED : 199712
DATA ITEMS CITED : 25
MOLECULAR FORMULA : C16-H27-Hg-N-O6-S.2Na
MOLECULAR WEIGHT : 608.07
WISWESSER LINE NOTATION : L5TJ AVM1YO1&1S-HG-1VQ A1 B1 B1 CVQ &-NA- 2
COMPOUND DESCRIPTOR : Drug
Organometallic
SYNONYMS/TRADE NAMES :
* N-(gamma-Carboxymethylmercaptomercuri-beta-methoxy)propylcamphoramic acid
disodium salt
* Disodium
N-(3-(carboxymethylthiomercuri)-2-methoxypropyl)-alpha-camphoramate
* Diucardyn sodium
* Mercaptomerin sodium
* Sodium mercaptomerin
* Thiomerin sodium

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 14 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of
National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
Ont., Canada)

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 8,316,1949

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 99,149,1950

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 99,149,1950

*** REVIEWS ***

ACGIH TLV-TWA 0.01 mg(Hg)/m3; STEL 0.03 mg/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997

*** U.S. STANDARDS AND REGULATIONS ***

MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3
DTLWS* "Documentation of the Threshold Limit Values for Substances in
Workroom Air," Supplements. For publisher information, see 85INA8.
Volume(issue)/page/year: 3,22,1973

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993

OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993

OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993

OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993

OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993

OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993

OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993

OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993

OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO MERCURY, ORGANO-air:TWA 0.01 mg/m3;STEL 0.03 mg/m3 (Sk)
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X5296
No. of Facilities: 7 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 628 (estimated)
No. of Female Employees: 314 (estimated)


*** END OF RECORD ***
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NAMECAS
Mercury,(3-(3-(3-carboxypropionyl)ureido)-2-methoxypropyl)hydroxy- 140-20-5
Mercury,(3-(3-carboxy-2,2,3-trimethylcyclopentanecarboxamido)-2-methoxypropyl) (hydrogen mercaptoacetato)- 20223-84-1
Mercury,(3-(3-carboxy-2,2,3-trimethylcyclopentanecarboxamido)-2-methoxypropyl)hydr oxy-, mixture with theophylline 8012-34-8
Mercury,(3-(((3-carboxy-2,2,3-trimethylcyclopentyl)carbonyl)amino)-2-methoxypropyl) (mercaptoacetato-S)-, disodiumsalt 21259-76-7
Mercury chloride 10112-91-1
Mercury(I) chloride 7546-30-7
Mandelic acid, alpha-benzyl-, 3-quinuclidinyl ester,hydrochloride 101756-48-3
Mercury(II) chloride 7487-94-7
Mercury,chloro(3-((4-amino-1,3,5-triazin-2-yl)amino)-2-hydroxypropyl)- 7487-94-7
Mercury, chloro(3-benzamido-2-methoxypropyl)- 7487-94-7
Mercury, chloro(2-(3-bromopropionamido)cyclohexyl)-,(E)- 73926-87-1
Mercury, chloro(2-chlorovinyl)- 5980-86-9
Mercury, chloro(dibutoxyphosphinyl)- 63869-01-2
Mercury, chloro(diisopropoxyphosphinyl)- 63869-02-3
Mercury, chloro(4-(dimethylamino)-2-sulfophenyl)- 63869-02-3
Mercury,chloro((3-(5,5-dimethyl-2,4-dioxo-3-imidazolidinyl)-2-methoxy)propyl)- 3477-28-9
Mercury,chloro(3-(2,2-dimethylpropionamido)-2-methoxypropyl)- 3477-28-9
Mandelic acid, alpha-(1-butenyl)-,1-methyl-4-piperidyl ester, (Z)- 101756-49-4
Mercury,chloro(3-(2,4-dioxo-1-imidazolidinyl)-2-methoxypropyl)- 3367-32-6
Mercury,chloro((3-(2,4-dioxo-3-imidazolidinyl)-2-methoxy)propyl)- 3367-29-1
Mercury,chloro((3-(2,4-dioxo-5-imidazolidinyl)-2-methoxy)propyl)- 3367-31-5
Mercury,chloro((3-(2,4-dioxo-1-methyl-3-imidazolidinyl)-2-methoxy)propyl)- 3367-28-0
Mercury,chloro((3-(2,4-dioxo-3-methyl-1-imidazolidinyl)-2-methoxy)propyl)- 67465-39-8
Mercury,chloro((3-(2,4-dioxo-3-methyl-5-imidazolidinyl)-2-methoxy)propyl)- 3367-30-4
Mercury, chloroethyl- 107-27-7
Mercury, chloro(2-furyl)- 5857-37-4
Mercury, chloro(2-hexanamidocyclohexyl)-, (E)- 73926-88-2
Mercury, chloro(2-hydroxy-3,5-dinitrophenyl)- 24579-91-7
Mandelic acid, alpha-(1-butenyl)-, 3-quinuclidinylester 101756-50-7
Mercury, chloro(2-hydroxyethyl)- 2090-53-1
Mercury,chloro(4-((2-hydroxy-1-naphthalenyl)azo)phenyl)- 3076-91-3
Mercury, chloro(o-hydroxyphenyl)- 90-03-9
Mercury, chloro(p-hydroxyphenyl)- 623-07-4
Mercury, (3-chloro-4-hydroxyphenyl)hydroxy- 538-04-5
Mercury, (3-chloro-6-hydroxyphenyl)hydroxy- 538-04-5
Mercury, chloro(1-hydroxy-4-sulfo-2-naphthyl)- 538-04-5
Mercury, chloro(3-methoxybicyclo(2.2.1)hept-2-yl)- 42085-80-3
Mercury, chloro(trans-2-methoxycyclooctyl)- 5185-84-2
Mercury, chloro(2-methoxyethyl)- 123-88-6
Mandelic acid, alpha-(1-butynyl)-,1-methyl-4-piperidyl ester 92956-50-8
Mercury, chloro(2-methoxy-3-(1-naphthamido)propyl)- 92956-50-8
Mercury, chloro(2-(3-methoxypropionamido)cyclohexyl)- 73926-89-3
Mercury, chloro(2-methoxy-3-propionamidopropyl)- 73926-89-3
Mercury, chloro(2-methoxy-3-ureidopropyl)- 62-37-3
Mercury, chloro(2-methoxy-3-valeramidopropyl)- 62-37-3
Mercury, chloromethyl- 115-09-3
Mercury, chloropentyl- 544-15-0
Mercury, chlorophenyl- 100-56-1
Mercury, chloro(N-phenylformamido)- 73940-90-6
Mercury, chloropropyl- 2440-40-6

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