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MSDS  : Mercury(II) oxide
CAS  : 21908-53-2
SYNONYMS  : * C.I. 77760 * Mercuric oxide * Mercuric oxide, red * Mercuric Oxide, Yellow * Mercury monoxide * Mercury(2+) oxide * Oxyde de mercure * Red mercuric oxide * Red oxide of mercury * Santar * Yellow mercuric oxide * Yellow precipitate
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OW8750000
CHEMICAL NAME : Mercury(II) oxide
CAS REGISTRY NUMBER : 21908-53-2
OTHER CAS REGISTRY NOS. : 1344-45-2
8028-34-0
LAST UPDATED : 199712
DATA ITEMS CITED : 37
MOLECULAR FORMULA : Hg-O
MOLECULAR WEIGHT : 216.59
WISWESSER LINE NOTATION : HG O
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* C.I. 77760
* Mercuric oxide
* Mercuric oxide, red
* Mercuric Oxide, Yellow
* Mercury monoxide
* Mercury(2+) oxide
* Oxyde de mercure
* Red mercuric oxide
* Red oxide of mercury
* Santar
* Yellow mercuric oxide
* Yellow precipitate

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB214-270

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 315 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 25(7),27,1981

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 22 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the
National Cancer Institute by The Institute of Chemical Biology, University
of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year:
PH43-64-886

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 16 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 25(7),27,1981

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 25(7),27,1981

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 10800 ug/kg
SEX/DURATION : female 5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
PWPSA8 Proceedings of the Western Pharmacology Society. (Univ. of
California Dept. of Pharmacology, Los Angeles, CA 90024) V.1- 1958-
Volume(issue)/page/year: 15,52,1972

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 10800 ug/kg
SEX/DURATION : female 19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
PWPSA8 Proceedings of the Western Pharmacology Society. (Univ. of
California Dept. of Pharmacology, Los Angeles, CA 90024) V.1- 1958-
Volume(issue)/page/year: 15,52,1972

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 34 mg/kg
SEX/DURATION : female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
APTOD9 Abstracts of Papers, Society of Toxicology. Annual Meetings.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
Volume(issue)/page/year: 19,A126,1980

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 225 mg/kg
SEX/DURATION : female 4-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 26(1),46A,1982

*** REVIEWS ***

ACGIH TLV-TWA 0.025 mg(Hg)/m3 (skin)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997

ACGIH TLV-Not classifiable as a human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997

IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,239,1993

IARC Cancer Review:Group 3
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,239,1993

TOXICOLOGY REVIEW
SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74.
Discontinued. Volume(issue)/page/year: 1,177,1971

*** U.S. STANDARDS AND REGULATIONS ***

MSHA STANDARD-air:TWA 0.05 mg(Hg)/m3
DTLWS* "Documentation of the Threshold Limit Values for Substances in
Workroom Air," Supplements. For publisher information, see 85INA8.
Volume(issue)/page/year: 3,22,1973

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-AUSTRALIA:TWA 0.05 mg(Hg)/m3;Skin JAN 1993

OEL-BELGIUM:TWA 0.05 mg(Hg)/m3;Skin JAN 1993

OEL-DENMARK:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-FINLAND:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-FRANCE:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-GERMANY:TWA 0.01 ppm (0.1 mg(Hg)/m3) JAN 1993

OEL-HUNGARY:TWA 0.02 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993

OEL-JAPAN:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-THE NETHERLANDS:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993

OEL-THE PHILIPPINES:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-POLAND:TWA 0.01 mg(Hg)/m3 JAN 1993

OEL-RUSSIA:TWA 0.05 mg(Hg)/m3;STEL 0.01 mg(Hg)/m3 JAN 1993

OEL-SWEDEN:TWA 0.05 mg(Hg)/m3 JAN 1993

OEL-THAILAND:STEL 0.05 mg(Hg)/m3 JAN 1993

OEL-UNITED KINGDOM:TWA 0.05 mg(Hg)/m3;STEL 0.15 mg(Hg)/m3 JAN 1993

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk)
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80143
No. of Facilities: 654 (estimated)
No. of Industries: 9
No. of Occupations: 10
No. of Employees: 3859 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80143
No. of Facilities: 506 (estimated)
No. of Industries: 10
No. of Occupations: 27
No. of Employees: 9517 (estimated)
No. of Female Employees: 3800 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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