*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OS3960000
CHEMICAL NAME : Melittin
CAS REGISTRY NUMBER : 37231-28-0
LAST UPDATED : 198809
DATA ITEMS CITED : 7
COMPOUND DESCRIPTOR : Drug
Mutagen
Natural Product
SYNONYMS/TRADE NAMES :
* Melittin-T
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 22,1921,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3500 ug/kg
TOXIC EFFECTS :
Behavioral - excitement
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
23EIAT "Venomous Animals and Their Venoms," Buecherl, W., and E.E. Buckley,
eds., 3 vols., New York, Academic Press, Inc., 1968-71
Volume(issue)/page/year: 3,61,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intracerebral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 860 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 22,308,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 12,139,1974
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 6 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity
Vascular - BP elevation not characterized in autonomic section
Lungs, Thorax, or Respiration - other changes
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 13,277,1975
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraarterial
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 13,277,1975
** MUTATION DATA **
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 100 pmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 5,1547,1984
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
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Melamine, N(sup 2),N(sup 2)-dipropyl-N(sup4)-phenethyl-, maleate (1:1)
| 26918-51-4 |
|
Melamine, N(sup 2)-ethyl-N(sup 4)-phenethyl-, maleate(1:1)
| 26918-50-3 |
|
Melamine, hexamethyl-
| 645-05-6 |
|
Melamine, hexa(methyl-d(sub 3))-
| 65886-69-3 |
|
Melamine, hexamethyl-, hydrochloride
| 15468-34-5 |
|
Melamine, N(sup 2)-hexyl-N(sup 4)-phenethyl-, maleate(1:1)
| 26918-54-7 |
|
Malvaviscus conzattii Greenm., extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family MalvaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,487,1984
| 26918-54-7 |
|
Melamine, methyl-
| 13452-77-2 |
|
Melamine, N(sup 2)-methyl-N(sup 4),N(sup 4),N(sup6),N(sup 6)-tetraethyl-
| 65886-68-2 |
|
Melamine, pentamethyl-
| 16268-62-5 |
|
Melamine, pentamethyl-, hydrochloride
| 16268-63-6 |
|
Melamine, polymer with formaldehyde
| 9003-08-1 |
|
Melamine, polymer with formaldehyde, butylated,pyrolyzate
| 9003-08-1 |
|
Melamine, N(sup 2),N(sup 2),N(sup 4),N(sup4)-tetramethyl-
| 2827-47-6 |
|
Melamine, N(sup 2),N(sup 2),N(sup 4),N(sup6)-tetramethyl-
| 16268-54-5 |
|
Melamine, N(sup 2),N(sup 4),N(sup 6)-trimethyl-
| 2827-46-5 |
|
Melamine, N(sup 2),N(sup 4),N(sup 6)-triphenethyl-
| 2827-46-5 |
|
Malvaviscus conzatti Greenm., flower extractSUBSTANCE DEFINITION :Belongs to the family MalvaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 2827-46-5 |
|
Melanin A
| 2827-46-5 |
|
Melanomycin
| 65454-27-5 |
|
Melanorrhoea woodsiana Scort., extractSUBSTANCE DEFINITION :Plant belonging to the family AnacardiaceaeREFERENCE :CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,1255 Howard St., San Francisco, CA 94103) V.6- 1958-Volume(issue)/page/year: 13,882,1965
| 65454-27-5 |
|
Melanosporin
| 102418-04-2 |
|
Melastoma malabathricum Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family MelastomaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 7,250,1969
| 102418-04-2 |
|
Melastoma normale D. Don., extractSUBSTANCE DEFINITION :Plant belonging to the family MelastomaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 102418-04-2 |
|
Melia azedarach Linn., extract
| 90063-92-6 |
|
Melianthus major Linn., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family SapindaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 90063-92-6 |
|
Melia toosendan Sieb. et Zucc., extract
| 90063-92-6 |
|
Melilotus alba Lamk., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family LeguminosaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 16,228,1978
| 90063-92-6 |
|
Mandarin oil
| 8008-31-9 |
|
Melilotus, extract
| 8008-31-9 |
|
Meciorant, dustSUBSTANCE DEFINITION :Composed of 47.3% CaCO3, 31.85% Ca(OH)2, 3.35% CaSO4, 2.07% CaCl2, 3.46%MgO, 1.6% FeO2, 1.09% NaCl, 12.82% SiO2REFERENCE :GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/OMezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-Volume(issue)/page/year: 50(7),72,1985
| 8008-31-9 |
|
Meliosma pungens Wall., stem bark extractSUBSTANCE DEFINITION :Plant belonging to the family SabiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974
| 8008-31-9 |
|
Meliosma simplicifolia (roxb.) Walp. ssp. pungens(wall. ex Wt. & Arn.) Beus., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family SabiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8008-31-9 |
|
Meliosma simplicifolia Walp., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family SabiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8008-31-9 |
|
Melittin
| 37231-28-0 |
|
Melittin (honeybee)
| 20449-79-0 |
|
Melocanna bambusoides Trin., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family PoaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,312,1984
| 20449-79-0 |
|
Melochia corchorifolia Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family SterculiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,487,1984
| 20449-79-0 |
|
Melodinus khasianus Hk. f., extractSUBSTANCE DEFINITION :Plant belonging to the family ApocynaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 20449-79-0 |
|
Mandelamide, N-(p-bromophenyl)-alpha-propyl-
| 39164-87-9 |
|
Melodinus monogynus Roxb., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family ApocynaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 39164-87-9 |
|
MelsmonSUBSTANCE DEFINITION :Placenta preparationsREFERENCE :NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,Japan) Volume(issue)/page/year: 6,854,1982
| 39164-87-9 |
|
Memecylon amplexicaule Var. malabarica C.B.Clarke,leaf extractSUBSTANCE DEFINITION :Plant belonging to the family MelastomaceaeREFERENCE :INDRBA Indian Drugs. (Indian Drugs Manufacturers' Assoc., 102B, PoonamChambers, Dr. A. B. Rd., Worli, Bombay 400 018, India) V.1- 1963-
| 39164-87-9 |
|
Memecylon andamanicum King, extractSUBSTANCE DEFINITION :Plant belonging to the family MemecylaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 39164-87-9 |
|
Memecylon angustifolium Wight, extractSUBSTANCE DEFINITION :Plant belonging to the family MemecylaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 39164-87-9 |
|
Memecylon edule Roxb., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family MelastomaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 39164-87-9 |
|
Memecylon edule Roxb. var. ovatum (J.E.Sm.)Cl.,extractSUBSTANCE DEFINITION :Plant belonging to the family MemecylaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 39164-87-9 |
|
Memecylon lushingtonii Gamble, extract excludingrootsSUBSTANCE DEFINITION :Plant belonging to the family MelastomaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 39164-87-9 |
|
Memecylon malabaricum (cl.) Cogn., leaf and twigextractSUBSTANCE DEFINITION :Plant belonging to the family MelastomaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 39164-87-9 |
|
Memecylon malbaricum (C.B.Cl) Cogn., leaf extractSUBSTANCE DEFINITION :Plant belonging to the family MalastomaceaeREFERENCE :INDRBA Indian Drugs. (Indian Drugs Manufacturers' Assoc., 102B, PoonamChambers, Dr. A. B. Rd., Worli, Bombay 400 018, India) V.1- 1963-Volume(issue)/page/year: 26,674,1989
| 39164-87-9 |
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