*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : PZ2950000
CHEMICAL NAME : Mithramycin, 3(sup C)-demethyl-4(sup C)-O-methyl-
CAS REGISTRY NUMBER : 12677-11-1
LAST UPDATED : 199609
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C52-H76-O24
MOLECULAR WEIGHT : 1085.28
SYNONYMS/TRADE NAMES :
* Varamycin
* Variamycin
* Variamycin glycoside
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,258,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1610 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,258,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2550 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,258,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,258,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1550 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,258,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 120 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,258,1976
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
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Mineral oil, petroleum distillates, solvent-dewaxedlight naphthenic (mild or no solvent-refining orhydrotreatment)
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Mineral oil, petroleum distillates, solvent-dewaxedlight naphthenic (severe solvent-refining and/orhydrotreatment)
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Mineral oil, petroleum distillates, solvent-refined(severe) heavy paraffinic
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Mineral oil, petroleum distillates catalytic dewaxedheavy naphtenic (severe solvent-refining and/orhydrotreatment)
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Mineral oil, petroleum distillates catalytic dewaxedlight naphthenic (mild or no solvent-refining orhydrotreatment)
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Methanone, (2-chloro-3-pyridinyl)(4-fluorophenyl)-
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Mineral oil, petroleum distillates catalytic dewaxedlight paraffinic (severe solvent-refiningand/orhydrotreatment
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Mineral oil, petroleum residual oils, acid-treated
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Mineral oil, white
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Mineral spirits
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Miniatomycin-M2
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Methanone, (6-chloro-3-pyridinyl)phenyl-
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Miniatomycin-M3
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Minomycin
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Miranol C2M
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Miromycin
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Mischocarpus sundaicus Bl., extractSUBSTANCE DEFINITION :Plant belonging to the family SapindaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
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Mithramycin
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Methanone, cyclohexyl(3,4-dihydroxy-5-nitrophenyl)-
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Mithramycin, 3(sup C)-demethyl-4(sup C)-O-methyl-
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Mitomycin R
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