*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QB9270000
CHEMICAL NAME : Monomycin
CAS REGISTRY NUMBER : 54597-56-7
LAST UPDATED : 199609
DATA ITEMS CITED : 7
COMPOUND DESCRIPTOR : Drug
Natural Product
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 5(4),10,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 510 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,433,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 615 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,433,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 77 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year:
10,947,1962
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Gastrointestinal - nausea or vomiting
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 5(4),10,1960
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis with appropriate
anesthesia
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 5(4),10,1960
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 1500 mg/kg/30D-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - changes in structure or function of salivary glands
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 5(4),10,1960
*** END OF RECORD ***
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Monoketoorganomycin
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Monomer FAH
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Methanone,(2,4-dichlorophenyl)(4-(beta-D-xylopyranosyloxy)phenyl)-, hemihydrate
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Monomycin
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Monotes glaber sprague, root extractSUBSTANCE DEFINITION :Beolonging to family Dipterocarpaceae and distributed in regions of ZimbabweREFERENCE :EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:25,77,1995
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Monstera deliciosa Liebm., leaf extract
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Montanoa frutescens, leaf extract
| 645-78-3 |
Methanone, dicyclopropyl-,O-(diethoxyphosphinyl)oxime
| 139087-70-0 |
Montanoa tomentosa, leaf extract
| 139087-70-0 |
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Montanoa tomentosa, leaf extract, semi-purified
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Mordenite
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Mordenite (AlNaH6(SiO3)5)
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Morimycin
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| 102149-28-0 |
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| 154027-26-6 |
Morinda angustifolia Roxb., extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 28,619,1990
| 154027-26-6 |
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| 154027-26-6 |
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| 154027-26-6 |
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| 154027-26-6 |
Morinda umbellata Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family RubiaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 24,48,1986
| 154027-26-6 |
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| 154027-26-6 |
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| 154027-26-6 |
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| 154027-26-6 |
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Methanone,(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)(4-hydroxyphenyl)-
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Moroyamycin B
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Morozol 2
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Morphanthridine, 8-chloro-6-(4-methyl-1-piperazinyl)-
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| 1977-12-4 |
Morphanthridine,5,6-dihydro-5-(2-(dimethylamino)ethyl)-,monohydrochloride
| 1977-12-4 |
Morphanthridine,5,6-dihydro-11-(3-dimethylamino-propylidene)-5-methyl-, di(cyclohexylsulfamate)
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Morphanthridine, 5,6-dihydro-5-(2-piperidinoethyl)-,dihydrochloride
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