RTECS NUMBER : BP0693200
CHEMICAL NAME : Ammonium,
(3-carbamoyl-3,3-diphenylpropyl)diisopropylmethyl-,
iodide
CAS REGISTRY NUMBER : 71-81-8
LAST UPDATED : 199806
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C23-H33-N2-O.I
MOLECULAR WEIGHT : 480.48
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* (3-Carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium iodide
* Darbid
* 2,2-Diphenyl-4-diisopropylaminobutyramide methiodide
* Dipramid
* Dipramide
* Isamid
* Isopropamide iodide
* Marygin-M
* 5579 MD
* Piaccamide
* Priamide
* Priazimide
* R 79
* Sanulcin
* SKF 4740
* Tyrimide
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: -,1318,1995
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1600 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Sense Organs and Special Senses (Eye) - lacrimation
Autonomic Nervous System - parasympatholytic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 103,120,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 120 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Sense Organs and Special Senses (Eye) - lacrimation
Autonomic Nervous System - parasympatholytic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 103,120,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12779 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 103,100,1955
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M4907
No. of Facilities: 200 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 801 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M4907
No. of Facilities: 68 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 690 (estimated)
No. of Female Employees: 414 (estimated)
*** END OF RECORD ***
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