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MSDS  
:
 2-Naphthalenesulfonic acid,
1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt
CAS  
:
 130-37-0
SYNONYMS  
:
 * Golagen K
* Hemoklot
* Hetrogen K
* Hetroge K premix
* Hykinone
* Ido-K
* Kalzon
* Kavitamin
* Kavitan
* Kawitan
* Klotogen
* Klotogen F
* Klotogen F 16
* Klotogen F 227
* K-Trombina
* Menadione sodium bisulfite
* Menadione sodium hydrogen sulfite
* Menaphthone sodium bisulfite
* Menaphthone sodium bisulphite
* MSBC
* Sodium menadione bisulfite
* 1,2,3,4-Tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid sodium
salt
* Vikasol
* Vitamin K injection
* Vitamin K3 sodium bisulfite

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QK3682000
CHEMICAL NAME           : 2-Naphthalenesulfonic acid,
                          1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt
CAS REGISTRY NUMBER     : 130-37-0
LAST UPDATED            : 199806
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C11-H9-O5-S.Na
MOLECULAR WEIGHT        : 276.25
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Golagen K
   * Hemoklot
   * Hetrogen K
   * Hetroge K premix
   * Hykinone
   * Ido-K
   * Kalzon
   * Kavitamin
   * Kavitan
   * Kawitan
   * Klotogen
   * Klotogen F
   * Klotogen F 16
   * Klotogen F 227
   * K-Trombina
   * Menadione sodium bisulfite
   * Menadione sodium hydrogen sulfite
   * Menaphthone sodium bisulfite
   * Menaphthone sodium bisulphite
   * MSBC
   * Sodium menadione bisulfite
   * 1,2,3,4-Tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid sodium  
   salt
   * Vikasol
   * Vitamin K injection
   * Vitamin K3 sodium bisulfite
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg/9D-I
TOXIC EFFECTS :
   Cardiac - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 124,193,1997
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 25 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 50 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 50 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 25 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 84777
       No. of Facilities: 21 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 705 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 84777
       No. of Facilities: 524 (estimated)
       No. of Industries: 2
       No. of Occupations: 3
       No. of Employees: 2658 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
1-Naphthaleneacetonitrile,alpha-(2-(N-benzyl-N-methylamino)ethyl)-alpha-isopropyl- 2572-70-5
1-Naphthalenesulfonic acid,4-hydroxy-3-((6-sulfo-2,4-xylyl)azo)-, disodium salt 4548-53-2
2-Naphthalenesulfonic acid, 5,6'-iminobis(1-hydroxy- 73816-77-0
Naphthalenesulfonic acid, isopropyl-, sodium salt 28348-64-3
2-Naphthalenesulfonic acid, 3,3'-methylenedi-,mercury salt 63766-15-4
2-Naphthalenesulfonic acid, 3,3'-methylenedi-,potassium salt 63766-16-5
2-Naphthalenesulfonic acid, 3,3'-methylenedi-, silversalt 31055-59-1
1-Naphthalenesulfonic acid,8-(phenylamino)-5-((4-((5-sulfo-1-naphthalenyl)azo)-1- naphthalenyl)azo)-, disodium salt 3071-73-6
2-Naphthalenesulfonic acid, sodium salt 532-02-5
2-Naphthalenesulfonic acid,1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt 130-37-0
1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- 605-65-2
1-Naphthaleneacetonitrile,alpha,alpha-bis(2-(bis(3-methyl-2-butenyl)amino)ethyl)- 50765-82-7
Naphthalene, 2,3,6,7-tetrabromo- 69881-92-1
1,4,5,8-Naphthalenetetracarboxylic acid 128-97-2
1,4,5,8-Naphthalenetetracarboxylic acid,1,8:4,5-dianhydride 81-30-1
Naphthalene, tetrachloro- 1335-88-2
Naphthalene, 2,3,6,7-tetrachloro- 34588-40-4
Naphthalene, 1,2,3,4-tetrahydro- 119-64-2
Naphthalene,1,2,3,4-tetrahydro-1-benzyloxy-2-dimethylamino-, (Z)- 58163-36-3
Naphthalene,1,2,3,4-tetrahydro-2-(p-chlorophenyl)-1-(p-(2,3-epoxypropoxy)phenyl)- 13073-72-8
Naphthalene,1,2,3,4-tetrahydro-1-(2-(dimethylamino)ethyl)-1-methyl- 101355-49-1
Naphthalene,1,2,3,4-tetrahydro-1,2-dimethyl-1-(2-(dimethylamino)ethyl)- 101449-01-8
1-Naphthaleneacetonitrile,alpha,alpha-bis(3-(diethylamino)propyl)- 13326-32-4
Naphthalene,1,2,3,4-tetrahydro-6-(2-(4-(ethylsulfonyl)phenyl)-1-methylethenyl)-1,1,4,4- tetramethyl-, (E)- 87719-32-2
Naphthalene,1,2,3,4-tetrahydro-6-ethyl-1,1,4,4-tetramethyl- 80-81-9
Naphthalene, 1,2,3,4-tetrahydromethyl- 31291-71-1
Naphthalene,1,2,3,4-tetrahydro-6-(1-methyl-2-(4-methylphenyl)ethenyl)-1,1,4,4- tetramethyl-, (E)- 71441-45-7
Naphthalene, 1,3,6,8-tetranitro- 28995-89-3
2-Naphthalenethiol 91-60-1
Naphthalene, trichloro- 1321-65-9
Naphthalene, 2,3,5-trinitro- 87185-24-8
1,4,6(5H)-Naphthalenetrione,2,3-dihydro-2-chloro-5-diazo-3-(3,7-dimethyl-2,6-octadienyl)-3,8-dihydroxy-7-methyl-2-(3-methyl-2-butenyl)-,(2-alpha,3-beta,3(E))- 110200-32-3
1,4,6(5H)-Naphthalenetrione,7,8-dihydro-8-(2-furanyl)- 130598-01-5
1-Naphthaleneacetonitrile,alpha,alpha-bis(2-(dimethylamino)ethyl)- 2810-20-0
1,3,6-Naphthalenetrisulfonic acid, 7-amino- 118-03-6
1,3,6-Naphthalenetrisulfonic acid, 8-amino-, disodiumsalt 118-03-6
1,3,6-Naphthalenetrisulfonic acid,7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-,tetrasodium salt 5850-44-2
2-Naphthalenevaleric acid,5,6,7,8-tetrahydro-alpha,alpha-dimethyl- 5850-44-2
1-Naphthalenol,2-(1-azabicyclo(2.2.2)oct-2-ylmethyl)-, hydrochloride 106200-16-2
1-Naphthalenol,4-((p-(bis(2-chloroethyl)amino)phenyl)amino)- 63978-92-7
1-Naphthalenol,5-chloro-2-((2-hydroxy-4-nitrophenyl)azo)-, cobaltsalt (2:1) 61969-42-4
2-Naphthalenol, decahydro- 825-51-4
1-Naphthalenol,decahydro-2-(1,3-benzodioxol-5-ylmethylene)- 69920-54-3
2-Naphthalenol,decahydro-1-(6-(2,2-dimethyl-6-methylenecyclohexyl)-4-methyl-3-hexenyl)- 2,5,5,8a-tetramethyl-,(1R-(1-alpha(E(S*)),2-beta,4a-beta,8a-alpha))- 473-03-0
1-Naphthaleneacetonitrile,alpha,alpha-bis(3-(dimethylamino)propyl)- 13326-29-9
2-Naphthalenol,decahydro-3-(4-(2-methoxyphenyl)-1-piperazinyl)-,monohydrochloride, E,E-(+-)- 13326-29-9
2-Naphthalenol,decahydro-3-(4-(2-methoxyphenyl)-1-piperazinyl)-,monohydrochloride, E,Z-(+-)- 13326-29-9
2-Naphthalenol, decahydro-6-(1-methylethyl)- 34131-99-2
2-Naphthalenol,decahydro-3-(4-phenyl-1-piperidinyl)-, hydrochloride,trans-(+-)- 120447-58-7
1-Naphthalenol,2-(9,10-dihydro-10-methyl-9-acridinyl)- 72517-59-0

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