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MSDS  : 2-Naphthalenol, 1-((4-methyl-2-nitrophenyl)azo)-
CAS  : 2425-85-6
SYNONYMS  : * Accosperse Toluidine Red XL * Adc Toluidine Red B * Atlasol Spirit Red 3 * Calcotone Toluidine Red YP * Carnelio Helio Red * Cerven pigment 3 * Chromatex Red J * C.I.12120 * C.I. Pigment Red 3 * C.P. Toluidine Toner A-2989 * C.P. Toluidine Toner A-2990 * C.P. Toluidine Toner Dark RS-3340 * C.P. Toluidine Toner Deep X-1865 * C.P. Toluidine Toner Light RS-3140 * C.P. Toluidine Toner RT-6101 * C.P. Toluidine Toner RT-6104 * Dainichi Permanent Red 4 R * D and C Red No. 35 * Deep Fastona Red * Duplex Toluidine Red L 20-3140 * Eljon Fast Scarlet PV Extra * Eljon Fast Scarlet RN * Enialit Light Red RL * Fastona Red B * Fastona Scarlet RL * Fastona Scarlet YS * Fast Red A (pigment) * Fast Red AB * Fast Red J * Fast Red JE * Fast Red R * Graphtol Red A-4RL * Hansa Red B * Hansa Red G * Hansa Scarlet RB * Hansa Scarlet RN * Hansa Scarlet RNC * Helio Fast Red BN * Helio Fast Red RL * Helio Fast Red RN * Helio Red RL * Helio Red Toner * Hispalit Fast Scarlet RN * Independence Red * Irgalite Fast Red P4R * Irgalite Fast Scarlet RND * Irgalite Red PV2 * Irgalite Red RNPX * Irgalite Scarlet RB * Isol Fast Red HB * Isol Fast Red RNB * Isol Fast Red RN2B * Isol Fast Red RNG * Isol Fast Red RN2G * Isol Toluidine Red HB * Isol Toluidine Red RNB * Isol Toluidine Red RN2B * Isol Toluidine Red RNG * Isol Toluidine Red RN2G * Kromon Helio Fast Red * Kromon Helio Fast Red YS * Lake Red 4R * Lake Red 4RII * Lithol Fast Scarlet RN * Lutetia Fast Red 3R * Lutetia Fast Scarlet RF * Lutetia Fast Scarlet RJN * 1-((4-Methyl-2-nitrophenyl)azo)-2-naphthalenol * Monolite Fast Scarlet CA * Monolite Fast Scarlet GSA * Monolite Fast Scarlet RB * Monolite Fast Scarlet RBA * Monolite Fast Scarlet RN * Monolite Fast Scarlet RNA * Monolite Fast Scarlet RNV * Monolite Fast Scarlet RT * NCI-C60366 * 1-((2-Nitro-4-methylphenyl)azo)-2-naphthol * 1-(o-Nitro-p-tolylazo)-2-naphthol * No. 2 Forthfast Scarlet * Oralith Red P4R * Permanent Red 4R * Pigment Red 3 * Pigment Red RL * Pigment Ruby * Pigment Scarlet * Pigment Scarlet * Pigment Scarlet B * Pigment Scarlet N * Pigment Scarlet R * Polymo Red FGN * Recolite Fast Red RBL * Recolite Fast Red BL * Recolite Fast Red RYL * Sanyo Scarlet Pure * Sanyo Scarlet Pure No. 1000 * Scarlet pigment RN * Segnale Light Red B * Segnale Light Red 2B * Segnale Light Red BR * Segnale Light Red C4R * Segnale Light Red RL * Siegle Red 1 * Siegle Red B * Siegle Red BB * Silogomma Red RLL * Silosol Red RBN * Silosol Red RN * Siloton Red BRLL * Siloton Red RLL * Symuler Fast Scarlet 4R * Syton Fast Scarlet RB * Syton Fast Scarlet RD * Syton Fast Scarlet RN * Tertropigment Red HAB * Tertropigment Scarlet LRN * Toluidine Red * Toluidine Red 10451 * Toluidine Red 3B * Toluidine Red BFB * Toluidine Red BFGG * Toluidine Red D 28-3930 * Toluidine Red Light * Toluidine Red M 20-3785 * Toluidine Red R * Toluidine Red 4R * Toluidine Red RT-115 * Toluidine Red Toner * Toluidine Red XL 20-3050 * Toluidine Toner * Toluidine Toner Dark 5040 * Toluidine Toner 4R X-2700 * Toluidine Toner HR X-2741 * Toluidine Toner Keep HR X-2742 * Toluidine Toner L 20-3300 * Toluidine Toner RT-252 * Versal Scarlet PRNL * Versal Scarlet RNL * Vulcafor Scarlet A
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : QK4247000
CHEMICAL NAME : 2-Naphthalenol, 1-((4-methyl-2-nitrophenyl)azo)-
CAS REGISTRY NUMBER : 2425-85-6
OTHER CAS REGISTRY NOS. : 12238-48-1
12240-01-6
12240-02-7
39310-30-0
LAST UPDATED : 199710
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C17-H13-N3-O3
MOLECULAR WEIGHT : 307.33
WISWESSER LINE NOTATION : L66J BNUNR D1 BNW& CQ
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Accosperse Toluidine Red XL
* Adc Toluidine Red B
* Atlasol Spirit Red 3
* Calcotone Toluidine Red YP
* Carnelio Helio Red
* Cerven pigment 3
* Chromatex Red J
* C.I.12120
* C.I. Pigment Red 3
* C.P. Toluidine Toner A-2989
* C.P. Toluidine Toner A-2990
* C.P. Toluidine Toner Dark RS-3340
* C.P. Toluidine Toner Deep X-1865
* C.P. Toluidine Toner Light RS-3140
* C.P. Toluidine Toner RT-6101
* C.P. Toluidine Toner RT-6104
* Dainichi Permanent Red 4 R
* D and C Red No. 35
* Deep Fastona Red
* Duplex Toluidine Red L 20-3140
* Eljon Fast Scarlet PV Extra
* Eljon Fast Scarlet RN
* Enialit Light Red RL
* Fastona Red B
* Fastona Scarlet RL
* Fastona Scarlet YS
* Fast Red A (pigment)
* Fast Red AB
* Fast Red J
* Fast Red JE
* Fast Red R
* Graphtol Red A-4RL
* Hansa Red B
* Hansa Red G
* Hansa Scarlet RB
* Hansa Scarlet RN
* Hansa Scarlet RNC
* Helio Fast Red BN
* Helio Fast Red RL
* Helio Fast Red RN
* Helio Red RL
* Helio Red Toner
* Hispalit Fast Scarlet RN
* Independence Red
* Irgalite Fast Red P4R
* Irgalite Fast Scarlet RND
* Irgalite Red PV2
* Irgalite Red RNPX
* Irgalite Scarlet RB
* Isol Fast Red HB
* Isol Fast Red RNB
* Isol Fast Red RN2B
* Isol Fast Red RNG
* Isol Fast Red RN2G
* Isol Toluidine Red HB
* Isol Toluidine Red RNB
* Isol Toluidine Red RN2B
* Isol Toluidine Red RNG
* Isol Toluidine Red RN2G
* Kromon Helio Fast Red
* Kromon Helio Fast Red YS
* Lake Red 4R
* Lake Red 4RII
* Lithol Fast Scarlet RN
* Lutetia Fast Red 3R
* Lutetia Fast Scarlet RF
* Lutetia Fast Scarlet RJN
* 1-((4-Methyl-2-nitrophenyl)azo)-2-naphthalenol
* Monolite Fast Scarlet CA
* Monolite Fast Scarlet GSA
* Monolite Fast Scarlet RB
* Monolite Fast Scarlet RBA
* Monolite Fast Scarlet RN
* Monolite Fast Scarlet RNA
* Monolite Fast Scarlet RNV
* Monolite Fast Scarlet RT
* NCI-C60366
* 1-((2-Nitro-4-methylphenyl)azo)-2-naphthol
* 1-(o-Nitro-p-tolylazo)-2-naphthol
* No. 2 Forthfast Scarlet
* Oralith Red P4R
* Permanent Red 4R
* Pigment Red 3
* Pigment Red RL
* Pigment Ruby
* Pigment Scarlet
* Pigment Scarlet
* Pigment Scarlet B
* Pigment Scarlet N
* Pigment Scarlet R
* Polymo Red FGN
* Recolite Fast Red RBL
* Recolite Fast Red BL
* Recolite Fast Red RYL
* Sanyo Scarlet Pure
* Sanyo Scarlet Pure No. 1000
* Scarlet pigment RN
* Segnale Light Red B
* Segnale Light Red 2B
* Segnale Light Red BR
* Segnale Light Red C4R
* Segnale Light Red RL
* Siegle Red 1
* Siegle Red B
* Siegle Red BB
* Silogomma Red RLL
* Silosol Red RBN
* Silosol Red RN
* Siloton Red BRLL
* Siloton Red RLL
* Symuler Fast Scarlet 4R
* Syton Fast Scarlet RB
* Syton Fast Scarlet RD
* Syton Fast Scarlet RN
* Tertropigment Red HAB
* Tertropigment Scarlet LRN
* Toluidine Red
* Toluidine Red 10451
* Toluidine Red 3B
* Toluidine Red BFB
* Toluidine Red BFGG
* Toluidine Red D 28-3930
* Toluidine Red Light
* Toluidine Red M 20-3785
* Toluidine Red R
* Toluidine Red 4R
* Toluidine Red RT-115
* Toluidine Red Toner
* Toluidine Red XL 20-3050
* Toluidine Toner
* Toluidine Toner Dark 5040
* Toluidine Toner 4R X-2700
* Toluidine Toner HR X-2741
* Toluidine Toner Keep HR X-2742
* Toluidine Toner L 20-3300
* Toluidine Toner RT-252
* Versal Scarlet PRNL
* Versal Scarlet RNL
* Vulcafor Scarlet A

*** HEALTH HAZARD DATA ***

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 42 gm/kg/14D-C
TOXIC EFFECTS :
Blood - normocytic anemia
Blood - changes in other cell count (unspecified)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
27,793,1989

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 68 gm/kg/90D-C
TOXIC EFFECTS :
Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
27,793,1989

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 84 gm/kg/2W-C
TOXIC EFFECTS :
Liver - changes in liver weight
Blood - changes in erythrocyte (RBC) count
Nutritional and Gross Metabolic - other changes
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 273 gm/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight
Related to Chronic Data - death
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 910 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4368 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
Kidney, Ureter, Bladder - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,1992

** MUTATION DATA **

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 3333 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl
7),1,1986

*** REVIEWS ***

IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,259,1993

IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,259,1993

IARC Cancer Review:Group 3
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,259,1993

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2109
No. of Facilities: 6944 (estimated)
No. of Industries: 78
No. of Occupations: 56
No. of Employees: 47730 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M2109
No. of Facilities: 4689 (estimated)
No. of Industries: 57
No. of Occupations: 53
No. of Employees: 51931 (estimated)
No. of Female Employees: 11615 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

NTP Carcinogenesis Studies (feed);some evidence:mouse,rat
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-407,92


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
2-Naphthalenol, 1-((2-methoxy-1-naphthalenyl)methyl)- 33230-77-2
2-Naphthalenol,1-((2-methoxy-1-naphthalenyl)methyl)-, acetate 68828-47-7
2-Naphthalenol, 6-methoxy-1-(2-nitroethenyl)- 103595-88-6
2-Naphthalenol, 1-((2-methoxyphenyl)azo)-, mixt. with9,10-anthracene, 1,4-diamino-2-methoxy- (33.4:6.0) 103595-88-6
1-Naphthalenol, methylcarbamate, mixt. with(1-alpha,2-alpha,3-beta,4-alpha,5-alpha,6-beta)-1,2,3,4,5,6-hexachlorocyclohexane and1,1'-(2,2,2-trichloroethylidene)bis(4-methoxybenzene) 67250-57-1
1-Naphthaleneacetonitrile,alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)- 42012-90-8
2-Naphthalenol, 1,1'-methylenebis(6-bromo- 68828-46-6
2-Naphthalenol, 1,1'-methylenebis(6-bromo-, diacetate 68828-50-2
2-Naphthalenol, 1,1'-methylenebis-, diacetate 60964-81-0
2-Naphthalenol, 1-((4-methyl-2-nitrophenyl)azo)- 2425-85-6
4a(2H)-Naphthalenol, octahydro-4,8a-dimethyl-,(4S-(4-alpha,4a-alpha,8a-beta))- 19700-21-1
2-Naphthalenol, 1-((4-(phenylazo)phenyl)azo)- 85-86-9
2-Naphthalenol, 1-(3-(phenylimino)-1-propenyl)-,acetate (ester) 96550-67-3
1-Naphthalenol, 2-(phenylmethyl)- 36441-32-4
2-Naphthalenol, sodium salt 875-83-2
1-Naphthalenol,1,2,3,4-tetrahydro-2-(1,3-benzodioxol-5-ylmethylene)- 69920-49-6
1-Naphthaleneacetonitrile,alpha-(2-bis(3-methyl-2-butenyl)amino)ethyl-alpha-ethyl-, hydrochloride 50765-78-1
2-Naphthalenol,1,2,3,4-tetrahydro-3-(benzylamino)-5,8-dimethoxy-,hydrochloride, (E)- 50765-78-1
2-Naphthalenol,1,2,3,4-tetrahydro-3-(cyclohexylamino)-5,8-dimethyoxy-, hydrochloride, (E)- 50765-78-1
2-Naphthalenol,1,2,3,4-tetrahydro-3-(diethylamino)-5,8-dimethoxy-,hydrochloride, (E)- 50765-78-1
2-Naphthalenol,1,2,3,4-tetrahydro-1-((4,5-dihydro-2-thiazolyl)amino)-, trans- 141034-15-3
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-((2-hydroxyethyl)amino)-, hydrochloride, (E)- 141034-15-3
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-((3-hydroxypropyl)amino)-, hydrochloride, (E)- 141034-15-3
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-(isopropylamino)-,(E)- 141034-15-3
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-(4-methyl-1-piperazinyl)-, dihydrochloride, (E)- 141034-15-3
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-morpholino-,hydrochloride, (E)- 141034-15-3
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-(1-piperazinyl)-,hydrochloride, (E)- 141034-15-3
1-Naphthaleneacetic acid, alpha-(3,3-diphenylpropyl)- 75226-94-7
1-Naphthaleneacetonitrile,alpha-(2-bis(3-methyl-2-butenyl)amino)ethyl-alpha-isopropyl-, hydrochloride 50765-79-2
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-piperidino-,hydrochloride, (E)- 50765-79-2
2-Naphthalenol,1,2,3,4-tetrahydro-5,8-dimethoxy-3-(1-pyrrolidinyl)-,hydrochloride, (E)- 50765-79-2
2-Naphthalenol,5,6,7,8-tetrahydro-8-(dimethylamino)-, hydrobromide 50765-79-2
1-Naphthalenol,1,2,3,4-tetrahydro-2-((4-(dimethylamino)phenyl)methyl)-, (alpha)-, hydrochloride 50765-79-2
1-Naphthalenol,1,2,3,4-tetrahydro-2-((4-(dimethylamino)phenyl)methyl)-, (beta)-, hydrochloride 50765-79-2
2-Naphthalenol,5,6,7,8-tetrahydro-6-(3-hydroxy-2-(2-hydroxyethyl)-2-methylcyclopentyl)-,(1S-(1-alpha(S*),2-beta,3-alpha))- 56502-09-1
2-Naphthalenol, 5,6,7,8-tetrahydro-, methylcarbamate 56502-09-1
2-Naphthalenol,1,2,3,4-tetrahydro-3-(4-phenyl-1-piperidinyl)-,hydrochloride, trans-(+-)- 56502-09-1
2-Naphthalenol,1-((2,2',3,3'-tetramethyl(1,1'-biphenyl)-4-yl)azo)- 150151-21-6
2-Naphthalenol, 1-(2-(1H-tetrazol-5-yl)ethyl)- 76167-91-4
1-Naphthaleneacetonitrile,alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-alpha-(3-methyl-2- butenyl)-, monohydrochloride 50765-81-6
1(4H)-Naphthalenone,2-(acetyloxy)-4-((3,4-dimethyl-5-isoxazolyl)imino)- 141723-90-2
1(4H)-Naphthalenone,8-amino-2,6-dibromo-5-hydroxy-4-imino- 26846-51-5
1(4H)-Naphthalenone, 2-amino-4-imino- 20513-06-8
1(4H)-Naphthalenone, 2-amino-4-imino-,monohydrochloride 5438-85-7
1(4H)-Naphthalenone,4-(p-bis(2-chloroethyl)aminophenyl)imino- 63979-13-5
1(2H)-Naphthalenone,7-chloro-3,4-dihydro-2-(3-pyridyl)- 786-97-0
1(4H)-Naphthalenone, 2,5-diamino-4-imino- 60599-33-9
1(2H)-Naphthalenone, 3,4-dihydro- 529-34-0
1(2H)-Naphthalenone,3,4-dihydro-2-(1,3-benzodioxol-5-ylmethylene)- 49545-71-3
1(2H)-Naphthalenone,3,4-dihydro-2-(1,3-benzodioxol-5-ylmethylene)-, (E)- 80554-35-4

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