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MSDS  : 2-Naphthalenesulfonic acid, 6-hydroxy-5-((p-sulfophenyl)azo)-, disodium salt
CAS  : 2783-94-0
SYNONYMS  : * Acid Yellow TRA * A.F. Yellow No. 5 * Aizen Food Yellow No. 5 * Alabaster No. 3 * Atul Sunset Yellow FCF * Canacert Sunset Yellow FCF * Certicol Sunset Yellow CFS * C.I. 15985 * C.I. Food Yellow 3, disodium salt * Cilefa Orange S * Disodium salt of 1-p-sulphophenylazo-2-naphthol-6-sulphonic acid * Dolkwal Sunset Yellow * E 110 * Edicol Supra Yellow FC * Eniacid Sunset Yellow * Eurocert Orange FCF * FD and C No. 6 * FD and C Yellow 6 * FD and C Yellow No. 6 * Food Yellow 3 * Food Yellow 6 * Gelborange-S * HD Sunset Yellow FCF * HD Sunset Yellow FCF Supra * Hexacol Sunset Yellow FCF * Hexacol Sunset Yellow FCF Supra * 6-Hydroxy-5-((p-sulfophenyl)azo)-2-naphthalenesulfonic acid, disodium salt * 6-Hydroxy-5-((4-sulfophenyl)azo)-2-naphthalenesulfonic acid, disodium salt * 6-Hydroxy-5-((p-sulphophenyl)azo)-2-naphthalenesulphonic acid, disodium salt * 6-Hydroxy-5-((4-sulphophenyl)azo)-2-naphthalenesulphonic acid, disodium salt * KCA Foodcol Sunset Yellow FCF * L. Orange Z2010 * Maple Sunset Yellow FCF * NCI-C53907 * Orange PAL * Orange II R * Orange Yellow S * Orange Yellow S. AF * Orange Yellow S. FQ * Para Orange * Standacol Sunset Yellow FCF * 1-p-Sulfophenylazo-2-hydroxynaphthalene-6-sulfonate, disodium salt * 1-p-Sulfophenylazo-2-naphthol-6-sulfonic acid, disodium salt * 1-p-Sulphophenylazo-2-naphthol-6-sulphonic acid, disodium salt * Sun Orange A Geigy * Sunset Yellow * Sunset Yellow FCF * Sunset Yellow FCF Supra * Sunset Yellow FU * Sunset Yellow FU Supra * Sunset Yellow Lake * SUN Yellow * SUN Yellow A-CE * SUN Yellow A-FDC * SUN Yellow Extra Conc. A Export * SUN Yellow Extra Pure A * SUN Yellow FCF * Usacert Yellow No. 6 * Usacert FD&C Yellow No. 6 * 1351 Yellow * 1899 Yellow * Yellow No. 6 * Yellow Orange S * Yellow Orange S Specially Pure * Yellow Orange Specially Pure 85 * Yellow sun * Yellow SY for food * Zlut potravinarska 3
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : QK2450000
CHEMICAL NAME : 2-Naphthalenesulfonic acid,
6-hydroxy-5-((p-sulfophenyl)azo)-, disodium salt
CAS REGISTRY NUMBER : 2783-94-0
LAST UPDATED : 199707
DATA ITEMS CITED : 19
MOLECULAR FORMULA : C16-H10-N2-O7-S2.2Na
MOLECULAR WEIGHT : 452.38
WISWESSER LINE NOTATION : L66J BNUNR DSWQ& CQ HSWQ &-NA- 2
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Acid Yellow TRA
* A.F. Yellow No. 5
* Aizen Food Yellow No. 5
* Alabaster No. 3
* Atul Sunset Yellow FCF
* Canacert Sunset Yellow FCF
* Certicol Sunset Yellow CFS
* C.I. 15985
* C.I. Food Yellow 3, disodium salt
* Cilefa Orange S
* Disodium salt of 1-p-sulphophenylazo-2-naphthol-6-sulphonic acid
* Dolkwal Sunset Yellow
* E 110
* Edicol Supra Yellow FC
* Eniacid Sunset Yellow
* Eurocert Orange FCF
* FD and C No. 6
* FD and C Yellow 6
* FD and C Yellow No. 6
* Food Yellow 3
* Food Yellow 6
* Gelborange-S
* HD Sunset Yellow FCF
* HD Sunset Yellow FCF Supra
* Hexacol Sunset Yellow FCF
* Hexacol Sunset Yellow FCF Supra
* 6-Hydroxy-5-((p-sulfophenyl)azo)-2-naphthalenesulfonic acid, disodium
salt
* 6-Hydroxy-5-((4-sulfophenyl)azo)-2-naphthalenesulfonic acid, disodium
salt
* 6-Hydroxy-5-((p-sulphophenyl)azo)-2-naphthalenesulphonic acid, disodium
salt
* 6-Hydroxy-5-((4-sulphophenyl)azo)-2-naphthalenesulphonic acid, disodium
salt
* KCA Foodcol Sunset Yellow FCF
* L. Orange Z2010
* Maple Sunset Yellow FCF
* NCI-C53907
* Orange PAL
* Orange II R
* Orange Yellow S
* Orange Yellow S. AF
* Orange Yellow S. FQ
* Para Orange
* Standacol Sunset Yellow FCF
* 1-p-Sulfophenylazo-2-hydroxynaphthalene-6-sulfonate, disodium salt
* 1-p-Sulfophenylazo-2-naphthol-6-sulfonic acid, disodium salt
* 1-p-Sulphophenylazo-2-naphthol-6-sulphonic acid, disodium salt
* Sun Orange A Geigy
* Sunset Yellow
* Sunset Yellow FCF
* Sunset Yellow FCF Supra
* Sunset Yellow FU
* Sunset Yellow FU Supra
* Sunset Yellow Lake
* SUN Yellow
* SUN Yellow A-CE
* SUN Yellow A-FDC
* SUN Yellow Extra Conc. A Export
* SUN Yellow Extra Pure A
* SUN Yellow FCF
* Usacert Yellow No. 6
* Usacert FD&C Yellow No. 6
* 1351 Yellow
* 1899 Yellow
* Yellow No. 6
* Yellow Orange S
* Yellow Orange S Specially Pure
* Yellow Orange Specially Pure 85
* Yellow sun
* Yellow SY for food
* Zlut potravinarska 3

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,747,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3800 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - coma
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,747,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >6 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,747,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4600 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - coma
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,747,1967

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 243 gm/kg/96D-C
TOXIC EFFECTS :
Gastrointestinal - other changes
Related to Chronic Data - changes in testicular weight
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,747,1967

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 476 mg/kg/28D-C
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 10,625,1958

** MUTATION DATA **

TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Rodent - mouse Lymphocyte
DOSE/DURATION : 1 gm/L
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
236,933,1987

TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 2 gm/L
REFERENCE :
GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring
St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year:
27,95,1981

*** REVIEWS ***

IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 8,257,1975

IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 8,257,1975

IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987

TOXICOLOGY REVIEW
ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For
publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2135
No. of Facilities: 2510 (estimated)
No. of Industries: 14
No. of Occupations: 21
No. of Employees: 17624 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M2135
No. of Facilities: 11207 (estimated)
No. of Industries: 67
No. of Occupations: 62
No. of Employees: 195835 (estimated)
No. of Female Employees: 103566 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Negative: Carcinogenicity-mouse/rat; Histidine
reversion-Ames test

EPA GENETOX PROGRAM 1988, Negative: S cerevisiae gene conversion

EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay; In vitro
SCE-nonhuman

EPA TSCA Section 8(b) CHEMICAL INVENTORY

NCI Carcinogenesis Bioassay (feed);inadequate studies:mouse,rat
NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
(Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
Volume(issue)/page/year: NCI-TR-208,81


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
2-Naphthalenesulfonic acid,5,5'-(4,4'-biphenylylenebis(azo))bis(6-amino-4-hydroxy-, disodium salt 2586-60-9
2-Naphthalenesulfonic acid,6-((p-(bis(2-chloroethyl)amino)phenyl)azo)- 101931-38-8
1-Naphthalenesulfonic acid,3,6-bis(1,1-dimethylethyl)-, ethyl ester 5560-69-0
2-Naphthalenesulfonic acid,3,7-bis(1,1-dimethylethyl)-, sodium salt 43064-33-1
2-Naphthalenesulfonic acid,6-((2,4-bis((sulfomethyl)amino)phenyl)azo)-3-((4-(p-((7-((2,4-bis((sulfomethyl)amino)phenyl)azo)-1-hydroxy-3-sulfo-2-naphthyl)azo)anilin o)-3-sulfophenyl)azo)-4-hydroxy-, heptasodium salt 2519-31-5
1-Naphthaleneacetic acid, 5,6,7,8-tetrahydro-,2-(dimethylamino)ethyl ester, hydrochloride 2519-31-5
1-Naphthalenesulfonic acid,4-(3-(p-butoxyphenyl)-2-thioureido)-, sodium salt 33326-68-0
1-Naphthalenesulfonic acid, 8-cyano-, sodium salt 33326-68-0
Naphthalenesulfonic acid, dibutyl-, sodium salt 25417-20-3
Naphthalenesulfonic acid, 2,6-di-tert-butyl-, sodiumsalt 1301-14-0
1-Naphthalenesulfonic acid,3,4-dihydro-3-((aminoiminomethyl)hydrazono)-4-oxo- 58851-83-5
3-Naphthalenesulfonic acid,1,2-dihydro-1-(dimethylamino)-4-phenyl- 52371-28-5
1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-,3-carbazone, sodium salt, dihydrate 52371-28-5
1-Naphthalenesulfonic acid, 7,8-dihydro-7,8-dioxo-,7-carbazone, sodium salt, dihydrate 52371-28-5
2-Naphthalenesulfonic acid, 5,6-dihydro-5,6-dioxo-,6-carbazone, sodium salt, dihydrate 52371-28-5
1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-,3-semicarbazone, ammonium salt, hydrate 52371-28-5
1-Naphthaleneacetic acid,alpha-(3,3-diphenyl-2-propenylidene)-, (E)- 75226-90-3
2-Naphthaleneacetic acid, 5,6,7,8-tetrahydro-,2-(dimethylamino)ethyl ester, hydrochloride 75226-90-3
1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-,sodium salt 521-24-4
1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-,3-thiosemicarbazone, ammonium salt, hydrate 521-24-4
1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-,3-thiosemicarbazone, sodium salt, hydrate 521-24-4
1-Naphthalenesulfonic acid, 5,6-dihydro-5,6-dioxo-,6-thiosemicarbazone, sodium salt, hydrate 521-24-4
2-Naphthalenesulfonic acid, 7,8-dihydro-7,8-dioxo-,7-thiosemicarbazone, sodium salt, hydrate 521-24-4
1-Naphthalenesulfonic acid,4,4'-((2,4-dihydroxy-5-(hydroxymethyl)-m-phenylene)bis(azo))di-, disodium salt 4553-89-3
1-Naphthalenesulfonic acid, compd. with3,4-dimethoxy-N-(1-methyl-2-pyrrolidinylidene)benzeneethanamine (1:1) 4553-89-3
2-Naphthalenesulfonic acid, compd. with(-)-alpha-4-(dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate (1:1), monohydrate 55557-30-7
2-Naphthalenesulfonic acid, compd. with(+)-alpha-(2-dimethylamino)-1-methylethyl-alpha-phenylphenethyl propionate (1:1) 17140-78-2
2-Naphthalenesulfonic acid, compd. with(alpha-S,1R)alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenylphenethyl propionate (1:1),monohydrate 26570-10-5
1-Naphthaleneacetic acid, alpha-(2'-thienyl)methyl-,sodium salt 1090-07-9
1-Naphthalenesulfonic acid,3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis (4-amino-, disodium salt 992-59-6
2-Naphthalenesulfonic acid, 5,7-dinitro-8-hydroxy- 483-84-1
2-Naphthalenesulfonic acid, 5,7-dinitro-8-hydroxy-,dipotassium salt 549-34-8
2-Naphthalenesulfonic acid, 5,7-dinitro-8-hydroxy-,disodium salt 846-70-8
Naphthalenesulfonic acid, dinonyl-, ammonium salt 67487-87-0
1-Naphthalenesulfonic acid, 2-hydroxy- 567-47-5
2-Naphthalenesulfonic acid, 6-hydroxy- 93-01-6
1-Naphthalenesulfonic acid, 4-hydroxy-3,4'-azodi-,disodium salt 3567-69-9
1-Naphthalenesulfonic acid,5-hydroxy-6-((m-((2-hydroxyethyl)sulfonyl)phenyl)azo)-, hydrogen sulfate (ester), disodium salt 19526-81-9
1-Naphthalenesulfonic acid,3-hydroxy-4-((1-hydroxy-2-naphthalenyl)azo)-,monosodium salt 3564-14-5
1-Naphthaleneacetonitrile,alpha-(2-(N-benzyl-N-methylamino)ethyl)- 1240-16-0
1-Naphthalenesulfonic acid,3-hydroxy-4-((1-hydroxy-2-naphthalenyl)azo)-7-nitro-,monosodium salt 1787-61-7
1-Naphthalenesulfonic acid,3-hydroxy-4-(2-hydroxy-1-naphthylazo)-, sodium salt 2538-85-4
1-Naphthalenesulfonic acid,4-hydroxy-3-((4'-((1-hydroxy-5-sulfo-2-naphthalenyl)azo)- 3,3'-dimethyl(1,1'-biphenyl)-4-yl)azo)-,disodium salt 6420-06-0
2-Naphthalenesulfonic acid,6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-,disodium salt 25956-17-6
2-Naphthalenesulfonic acid,4-hydroxy-7-(methylamino)- 22346-43-6
1-Naphthalenesulfonic acid,2-((2-hydroxy-1-naphthalenyl)azo)-, monosodium salt 1248-18-6
1-Naphthalenesulfonic acid,4-((2-hydroxy-1-naphthalenyl)azo)-, monosodium salt 1658-56-6
2-Naphthalenesulfonic acid, 6-hydroxy-5-(phenylazo)-,monosodium salt 1934-20-9
1-Naphthalenesulfonic acid,4-((2-hydroxy-6-sulfo-1-naphthalenyl)azo)-, disodiumsalt 2302-96-7
2-Naphthalenesulfonic acid,6-hydroxy-5-((p-sulfophenyl)azo)-, disodium salt 2783-94-0

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