*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QQ3450000
CHEMICAL NAME : Neuraminidase
CAS REGISTRY NUMBER : 9001-67-6
LAST UPDATED : 199701
DATA ITEMS CITED : 3
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* E.C. 3.2.1.18
* alpha-Neuraminidase
* Sialidase
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE : 4000 iu/kg
SEX/DURATION : female 4-6 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
REFERENCE :
NMJOAA Nagoya Medical Journal. (Nagoya City Univ. Medical School, Kawasumi,
Mizuho-cho, Mizuho-ku, Nagoya 467, Japan) V.1- 1953-
Volume(issue)/page/year: 22,135,1977
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE : 2000 iu/kg
SEX/DURATION : female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
NMJOAA Nagoya Medical Journal. (Nagoya City Univ. Medical School, Kawasumi,
Mizuho-cho, Mizuho-ku, Nagoya 467, Japan) V.1- 1953-
Volume(issue)/page/year: 22,135,1977
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
|
|
|