RTECS NUMBER : RC9700000
CHEMICAL NAME : 21-Nor-1,14-secoeburnamenin-20-ol, 14,15-dihydro-,
(3-alpha,16-alpha)-
CAS REGISTRY NUMBER : 106498-99-1
BEILSTEIN REFERENCE NO. : 4786095
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C18-H24-N2-O
MOLECULAR WEIGHT : 284.44
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* (-)-(1S,12bS)-1-Ethyl-1-hydroxymethyl-1,2,3,4,6,7,12,12b-octahydroindolo
(1,3-a)quinolizine
* (3-alpha,16-alpha)-14,15-Dihydro-21-nor-1,14-secoeburnamenin-20-ol
* RGH 2981
* Vintoperol
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
11,853,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 8900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
11,853,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
11,853,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 6600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
11,853,1986
*** END OF RECORD ***
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