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MSDS  : Phenol, 4,4'-isopropylidenebis(2,6-dichloro-
CAS  : 79-95-8
SYNONYMS  : * 2,2-Bis(3,5-dichloro-4-hydroxyphenyl)propane * 2,2-Bis(4-hydroxy-3,5-dichlorophenyl)propane * 4,4'-Isopropylidenebis(2,6-dichlorophenol) * 4,4'-(1-Methylethylidene)bis(2,6-dichlorophenol) * NSC 18248 * Phenol, 4,4'-(1-methylethylidene)bis(2,6-dichloro- * Tetrachlordian * 2,2',6,6'-Tetrachlorobisphenol A
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : SL6250000
CHEMICAL NAME : Phenol, 4,4'-isopropylidenebis(2,6-dichloro-
CAS REGISTRY NUMBER : 79-95-8
BEILSTEIN REFERENCE NO. : 2059573
REFERENCE : 3-06-00-05462 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C15-H12-Cl4-O2
MOLECULAR WEIGHT : 366.07
WISWESSER LINE NOTATION : QR BG FG DX1&1&R DQ BG FG
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* 2,2-Bis(3,5-dichloro-4-hydroxyphenyl)propane
* 2,2-Bis(4-hydroxy-3,5-dichlorophenyl)propane
* 4,4'-Isopropylidenebis(2,6-dichlorophenol)
* 4,4'-(1-Methylethylidene)bis(2,6-dichlorophenol)
* NSC 18248
* Phenol, 4,4'-(1-methylethylidene)bis(2,6-dichloro-
* Tetrachlordian
* 2,2',6,6'-Tetrachlorobisphenol A

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,536,1986

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 7432 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(2),64,1984

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5050 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(2),64,1984

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 67500 mg/kg/45D-I
TOXIC EFFECTS :
Blood - microcytosis with or without anemia
Blood - changes in erythrocyte (RBC) count
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(2),64,1984

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 9750 mg/kg/26W-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells
Blood - other changes
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(2),64,1984

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Phenol, isopropylated, phosphate (31) 68937-41-7
Phenol, 4-isopropyl-2,6-dinitro- 4097-47-6
Phenol, 4-arsenoso-2-chloro- 4097-47-6
Phenol, 4,4'-isopropylidenebis(2,6-dichloro- 79-95-8
Phenol, 4,4'-isopropylidenedi- 80-05-7
Phenol, 4,4'-isopropylidenedi-, dimer with1-chloro-2,3-epoxypropane 25068-38-6
Phenol, 4,4'-isopropylidenedi-, monomer with1-chloro-2,3-epoxypropane 25068-38-6
Phenol, 4,4'-isopropylidenedi-, polymer with1-chloro-2,3-epoxypropane 25068-38-6
Phenol, 4,4'-isopropylidenedi-, tetramer with1-chloro-2,3-epoxypropane 25068-38-6
Phenol, 2-isopropyl-4-methyl- 4427-56-9
Phenol, 2-isopropyl-6-methyl- 3228-04-4
Phenol, 2-isopropyl-4-(alpha-methylbenzyl)-5-methyl- 3228-04-4
Phenol, 2-isopropyl-6-(1-methylbutyl)- 74926-98-0
Phenol, 4-arsenoso-2,6-diamino-, hydrochloride 74926-98-0
Phenol,6-isopropyl-3-methyl-2,2'-methylenebis(4-chloro- 74926-98-0
Phenol, 2-isopropyl-6-(1-methylpentyl)- 74926-99-1
Phenol, m-(3-isopropyl-1-methyl-3-pyrrolidinyl)- 38906-41-1
Phenol, 2-isopropyl-6-propyl- 74663-48-2
Phenol, p-(3-mercapto-as-triazin-5-yl)- 74663-48-2
Phenol, m-methoxy- 150-19-6
Phenol, o-methoxy- 90-05-1
Phenol, p-methoxy- 150-76-5
Phenol, o-methoxy-, chlorinated 150-76-5
Phenol,2-methoxy-6-(((2-methoxyethyl)amino)methyl)-4-(2-propenyl)- 54219-79-3
Phenol,4-arsenoso-2-((4,6-diamino-s-triazin-2-yl)amino)- 54219-79-3
Phenol,2-methoxy-6-(((3-methoxypropyl)amino)methyl)-4-(2-propenyl)- 54219-82-8
Phenol,3-(9-methoxy-3-methyl-3-azabicyclo(3.3.1)non-9-yl)-,syn- 42471-68-1
Phenol,3-methoxy-4-(3-methyl-2-butenyl)-5-(2-phenylethenyl)-, (E)- 64125-60-6
Phenol,4-methoxy-2-(2-methyl-1-((methylamino)methyl)propyl)-5-(pentylthio)-, (Z)-2- butenedioate (1:1) (salt) 129658-16-8
Phenol,4-methoxy-2-(4-(4-methyl-1-piperazinyl)-1-phenylbutyl)-, dihydrochloride 129841-29-8
Phenol, 2-methoxy-4-nitro- 3251-56-7
Phenol, 5-methoxy-2-nitroso- 13895-38-0
Phenol, 2-methoxy-4-((2-oxazolin-2-yl)amino)methyl- 101952-91-4
Phenol, 2-methoxy-4-(2-(phenethylamino)ethyl)-,hydrochloride 70044-81-4
Phenol,3-(9-methoxy-3-phenethyl-3-azabicyclo(3.3.1)non-9-yl)-, syn- 42471-70-5
Phenol, m-arsenoso-, dihydrate 42471-70-5
Phenol,3-(1-(p-methoxyphenethyl)-3-propyl-3-pyrrolidinyl)- 69745-68-2
Phenol,2-(5-((2-methoxyphenyl)amino)-4-phenyl-4H-1,2,4-triazol-3-yl)- 82619-93-0
Phenol,2-(5-((4-methoxyphenyl)amino)-4-phenyl-4H-1,2,4-triazol-3-yl)- 82619-92-9
Phenol, p-((p-methoxyphenyl)azo)- 2496-25-5
Phenol, p-((p-methoxyphenyl)azo)-, piperazine salt 2496-25-5
Phenol,o-(4-(m-methoxyphenyl)-3H-1,5-benzodiazepin-2-yl)- 2496-25-5
Phenol,o-(4-(o-methoxyphenyl)-3H-1,5-benzodiazepin-2-yl)- 2496-25-5
Phenol, 4-(6-methoxy-2-phenylbenzo(b)thien-3-yl)- 21382-73-0
Phenol, 2-(2-(4-methoxyphenyl)cylopropyl)- 40603-35-8
Phenol,p-(6-methoxy-2-phenyl-3,4-dihydro-1-naphthyl)- 1729-38-0
Phenol, 4-arsenoso-2-(dimethylamino)- 1729-38-0
Phenol, 2-methoxy-6-(((2-phenylethyl)amino)methyl)- 1729-38-0
Phenol,2-methoxy-5-(5-((4-phenyl-1-piperazinyl)methyl)-1,3,4-oxadiazol-2-yl)- 127718-47-2
Phenol,4-((5-(4-methoxyphenyl)-2H-tetrazol-2-yl)methyl)-2,6-dimethyl- 104186-18-7

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