Ammonium,
ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(o-sulfo
phenyl)benzylidene)-
2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-,
hydroxide, inner salt, disodium salt
CAS
:
3844-45-9
SYNONYMS
:
* Acid Sky Blue A
* Aizen Food Blue No. 2
* 1206 Blue
* Blue 1206
* Brilliant Blue FCD No. 1
* Brilliant Blue FCF Supra
* Canacert Brilliant Blue FCF
* C.I. Acid Blue 9, disodium salt
* C.I. Food Blue 2
* Cosmetic Blue Lake
* Dolkwal Brilliant Blue
* FD and C Blue 1
* FD and C Blue No. 1
* FDC Blue No. 1
* Fenazo Blue XI
* Food Blue 2
* Food Blue Dye No. 1
* Hexacol Brilliant Blue A
* Intracid Pure Blue L
* Japan Blue 1
* Japan Blue No. 1
* Merantine Blue EG
* Modr Brilantni FCF
* Modr Kysela 9
* Modr Potravinarska 2
* Usacert Blue No. 1
* Usacert FD and C Blue No. 1
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : BQ4725000
CHEMICAL NAME : Ammonium,
ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(o-sulfo
phenyl)benzylidene)-
2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-,
hydroxide, inner salt, disodium salt
CAS REGISTRY NUMBER : 3844-45-9
OTHER CAS REGISTRY NOS. : 70992-30-2
LAST UPDATED : 199710
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C37-H36-N2-O9-S3.2Na
MOLECULAR WEIGHT : 794.91
WISWESSER LINE NOTATION : L6Y DYJ AUYR BSWQ&R DN2&1R CSWQ&& DUK2&1R CSWQ &Q
&-NA- 2
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Acid Sky Blue A
* Aizen Food Blue No. 2
* 1206 Blue
* Blue 1206
* Brilliant Blue FCD No. 1
* Brilliant Blue FCF Supra
* Canacert Brilliant Blue FCF
* C.I. Acid Blue 9, disodium salt
* C.I. Food Blue 2
* Cosmetic Blue Lake
* Dolkwal Brilliant Blue
* FD and C Blue 1
* FD and C Blue No. 1
* FDC Blue No. 1
* Fenazo Blue XI
* Food Blue 2
* Food Blue Dye No. 1
* Hexacol Brilliant Blue A
* Intracid Pure Blue L
* Japan Blue 1
* Japan Blue No. 1
* Merantine Blue EG
* Modr Brilantni FCF
* Modr Kysela 9
* Modr Potravinarska 2
* Usacert Blue No. 1
* Usacert FD and C Blue No. 1
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4600 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75,
1903-71. For publisher information, see JCROD7. Volume(issue)/page/year:
64,287,1961
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5500 mg/kg/97W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75,
1903-71. For publisher information, see JCROD7. Volume(issue)/page/year:
64,287,1961
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4580 mg/kg/62W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
Blood - lymphoma, including Hodgkin's disease
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 38B,27,1966
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2 gm/kg/94W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 38B,27,1966
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 4400 mg/L
REFERENCE :
GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring
St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year:
27,95,1981
*** REVIEWS ***
IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 16,171,1978
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 16,171,1978
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4021
No. of Facilities: 2869 (estimated)
No. of Industries: 23
No. of Occupations: 45
No. of Employees: 57876 (estimated)
No. of Female Employees: 30139 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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